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4 Star Hotels in Colon

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Featured 4 Star Colon Hotels

Decapolis Hotel Panama City
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $143 per night from Jan 3 to Jan 4
$143
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
Decapolis Hotel Panama City
Novotel Panama City
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $97 per night from Jan 22 to Jan 23
$97
includes taxes & fees
Jan 22 - Jan 23, 2025
Stay at this 4-star family-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Novotel Panama City
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $103 per night from Jan 4 to Jan 5
$103
includes taxes & fees
Jan 4 - Jan 5, 2025
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
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Sheraton Grand Panama
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $158 per night from Jan 10 to Jan 11
$158
includes taxes & fees
Jan 10 - Jan 11, 2025
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Sheraton Grand Panama
Residence Inn by Marriott Panama City
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $157 per night from Jan 25 to Jan 26
$157
includes taxes & fees
Jan 25 - Jan 26, 2025
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Residence Inn by Marriott Panama City
Marriott Panama Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $157 per night from Jan 3 to Jan 4
$157
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Marriott Panama Hotel
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $140 per night from Jan 3 to Jan 4
$140
includes taxes & fees
Jan 3 - Jan 4, 2025
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Ramada Plaza By Wyndham Panama Punta Pacífica
Megapolis Hotel Panamá
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $165 per night from Jan 2 to Jan 3
$165
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Megapolis Hotel Panamá
Las Americas Golden Tower Panama
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $188 per night from Jan 13 to Jan 14
$188
includes taxes & fees
Jan 13 - Jan 14, 2025
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
Las Americas Golden Tower Panama
Studio Coliving
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $61 per night from Jan 2 to Jan 3
$61
includes taxes & fees
Jan 2 - Jan 3, 2025
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
Studio Coliving
Exe Oriental Panama
4 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Colon 2000
The price is $63 per night from Jan 29 to Jan 30
$63
includes taxes & fees
Jan 29 - Jan 30, 2025
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Albrook Shopping Mall and ...
Exe Oriental Panama
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
Fully refundableReserve now, pay when you stay
  • 2 hours drive from Colon 2000
The price is $325 per night from Jan 26 to Jan 27
$325
includes taxes & fees
Jan 26 - Jan 27, 2025
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
Dreams Playa Bonita Panama - All Inclusive
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Colon

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Colon for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Colon as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Colon 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Colon starting at $61 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Colon 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.