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5 Star Hotels in Colon

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Featured 5 Star Colon Hotels

Hotel Riu Plaza Panama
5 out of 5
  • 1 hour drive from Colon Free Zone
The price is $116 per night from Dec 16 to Dec 17
$116
includes taxes & fees
Dec 16 - Dec 17
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
Hotel Riu Plaza Panama
Waldorf Astoria Panama
5 out of 5
  • 1 hour drive from Colon Free Zone
The price is $166 per night from Dec 7 to Dec 8
$166
includes taxes & fees
Dec 7 - Dec 8
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
Waldorf Astoria Panama
JW Marriott Panama
5 out of 5
  • 1 hour drive from Colon Free Zone
The price is $166 per night from Dec 13 to Dec 14
$166
includes taxes & fees
Dec 13 - Dec 14
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
JW Marriott Panama
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W Panama
5 out of 5
  • 1 hour drive from Colon Free Zone
The price is $122 per night from Dec 13 to Dec 14
$122
includes taxes & fees
Dec 13 - Dec 14
Stay at this 5-star luxury hotel in Panama City. Enjoy 2 restaurants, 3 spa tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
W Panama
Sofitel Legend Casco Viejo, Panama City
5 out of 5
  • 1 hour drive from Colon Free Zone
The price is $322 per night from Dec 19 to Dec 20
$322
includes taxes & fees
Dec 19 - Dec 20
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
Sofitel Legend Casco Viejo, Panama City
Hilton Panama
5 out of 5
  • 1 hour drive from Colon Free Zone
The price is $149 per night from Dec 13 to Dec 14
$149
includes taxes & fees
Dec 13 - Dec 14
Stay at this 5-star luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our ...
Hilton Panama
Bristol Panama, a Registry Collection Hotel
5 out of 5
  • 1 hour drive from Colon Free Zone
The price is $194 per night from Dec 6 to Dec 7
$194
includes taxes & fees
Dec 6 - Dec 7
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff and the property ...
Bristol Panama, a Registry Collection Hotel
The Westin Playa Bonita Panama
5 out of 5
  • 2 hours drive from Colon Free Zone
The price is $183 per night from Dec 5 to Dec 6
$183
includes taxes & fees
Dec 5 - Dec 6
Stay at this 5-star luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
The Westin Playa Bonita Panama
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The price is $186 per night from Dec 13 to Dec 14
$186
includes taxes & fees
Dec 13 - Dec 14
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Veneto Hotel & Casino
5 out of 5
  • 1 hour drive from Colon Free Zone
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Via ...
Veneto Hotel & Casino
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5-Star Hotel in Colon

It’s time. No more meh motels and so-so stays. This vacation it’s all about living it up, and that starts with a great hotel. You want first-class service and award-winning restaurants. Well, let us introduce you to a 5-star hotel in Colon.

So nice you’ll blink twice

What makes a hotel worthy of supreme star-age? For starters, the service has to be top-notch and personalized. These hotels often have 24-hour room service, a welcome gift upon your arrival, and help you with your bags—even if you travel light.

Are they nicer? Heck yeah, they are! Most 5-star hotels have jaw-dropping aesthetics that give an authentic feel of class. And we’re not talking about that faux-gold soap dish your Aunt Tilda puts out for the guests—it’s the real deal.

Stars in your eyes

Are 5-stars hotels worth it? If you like the finer things in life, then yes, they sure are. But we also know you’re the type that likes to get your caviar on a fish stick budget. We’re right there with you, and that is why we make it easy to find the best 5-star hotel in Colon for you. Sort by:

  • Price: Want to live large, but keep that budget balanced? We got you. We have 5-star hotels starting at $116.

  • Amenities: Colon skyline view? Maybe a heated indoor pool? Looking for a Michelin-star restaurant? Search for the hotels that have the amenities you desire.

  • Hotwire Hot Rate: We’ll tell you the name of the hotel after you book, and you might just save a ton.

When you’re looking for the top 5-star hotels in Colon—but don’t want to pay top dollar—let us help you out. You can get that posh palace of your dreams, and have money left to take on Colon your way.