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Featured 4 Star Main South Hotels

Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Westborough. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...

Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Milford. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions ...

Fully refundableReserve now, pay when you stay
Stay at this 4-star luxury hotel in Worcester. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular Main South Hotels
- Motel 6 Framingham, MA - Boston West
- DoubleTree by Hilton Hotel Boston - Westborough
- Wellsworth Hotel
- Publick House Historic Inn and Country Motor Lodge
- Best Western Royal Plaza Hotel & Trade Center
- Courtyard by Marriott Boston Marlborough
- Hyatt Place Marlborough/Apex Center
- Sonesta Select Boston Milford
- Comfort Inn Auburn - Worcester
- Hilton Garden Inn Boston/Marlborough
- Extended Stay America Suites Boston Westborough Computer Dr
Top Attractions in Main South
- Hotels near Clark University (0.11 mi)
- Hotels near Burnside Fountain (0.13 mi)
- Hotels near DCU Center (1.39 mi)
- Hotels near Union Station (1.47 mi)
- Hotels near Old Sturbridge Village (17.28 mi)
- Hotels near Worcester Polytechnic Institute (1.71 mi)
- Hotels near Apex Entertainment Center (13.39 mi)
- Hotels near New England Sports Center (13.72 mi)
- Hotels near College of the Holy Cross (1.22 mi)
- Hotels near Wachusett Mountain Ski Area (17.33 mi)
- Hotels near Southwick's Zoo (17.65 mi)
- Hotels near Tower Hill Botanic Garden (8.99 mi)
- Hotels near UMass Memorial Medical Center (2.08 mi)
- Hotels near Indian Ranch (13.68 mi)
- Hotels near Worcester Art Museum (1.83 mi)
- Hotels near Thompson International Speedway (18.55 mi)
- Hotels near New England Baseball Complex (8.16 mi)
- Hotels near The Hanover Theatre for the Performing Arts (1.11 mi)
- Hotels near Hopkinton State Park (14.76 mi)
- Hotels near Quinsigamond State Park (3.49 mi)
Nearby Cities
- Worcester Hotels (1.21 mi)
- Marlborough Hotels (15.16 mi)
- Sturbridge Hotels (16.5 mi)
- Framingham Hotels (20.7 mi)
- Westborough Hotels (10.65 mi)
- Milford Hotels (17.33 mi)
- Leominster Hotels (19.17 mi)
- Auburn Hotels (3.99 mi)
- Southbridge Hotels (16.34 mi)
- Brimfield Hotels (21.39 mi)
- Shrewsbury Hotels (6.29 mi)
- Sudbury Hotels (22.56 mi)
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Car Rentals Near Main South
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