Search for Cheap Deals on4 Star Hotels in Main South
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured 4 Star Main South Hotels

Fully refundableReserve now, pay when you stay
The price is $142 per night from May 4 to May 5
$142
includes taxes & fees
May 4 - May 5
Stay at this 4-star business-friendly hotel in Westborough. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...

Fully refundableReserve now, pay when you stay
The price is $342 per night from Apr 27 to Apr 28
$342
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4-star luxury hotel in Worcester. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...

Fully refundableReserve now, pay when you stay
The price is $146 per night from May 27 to May 28
$146
includes taxes & fees
May 27 - May 28
Stay at this 4-star hotel in Milford. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular Main South Hotels
- DoubleTree by Hilton Hotel Boston - Westborough
- Wellsworth Hotel
- Courtyard by Marriott Boston Marlborough
- Comfort Inn Auburn - Worcester
- Best Western Royal Plaza Hotel & Trade Center
- Motel 6 Framingham, MA - Boston West
- Hyatt Place Marlborough/Apex Center
- Hilton Garden Inn Worcester
- Publick House Historic Inn and Country Motor Lodge
- Extended Stay America Suites Boston Marlborough
- AC Hotel by Marriott Worcester
Top Attractions in Main South
- Hotels near Clark University (0.11 mi)
- Hotels near Burnside Fountain (0.13 mi)
- Hotels near DCU Center (1.39 mi)
- Hotels near Old Sturbridge Village (17.28 mi)
- Hotels near Union Station (1.47 mi)
- Hotels near Apex Entertainment Center (13.39 mi)
- Hotels near College of the Holy Cross (1.22 mi)
- Hotels near Worcester Polytechnic Institute (1.71 mi)
- Hotels near New England Sports Center (13.72 mi)
- Hotels near Wachusett Mountain Ski Area (17.33 mi)
- Hotels near Southwick's Zoo (17.65 mi)
- Hotels near UMass Memorial Medical Center (2.08 mi)
- Hotels near Indian Ranch (13.68 mi)
- Hotels near Tower Hill Botanic Garden (8.99 mi)
- Hotels near Worcester Art Museum (1.83 mi)
- Hotels near The Hanover Theatre for the Performing Arts (1.11 mi)
- Hotels near New England Baseball Complex (8.16 mi)
- Hotels near Thompson International Speedway (18.55 mi)
- Hotels near Lake Webster (14.25 mi)
- Hotels near Hopkinton State Park (14.76 mi)
Nearby Cities
- Worcester Hotels (1.21 mi)
- Sturbridge Hotels (16.5 mi)
- Marlborough Hotels (15.16 mi)
- Framingham Hotels (20.7 mi)
- Westborough Hotels (10.65 mi)
- Leominster Hotels (19.17 mi)
- Auburn Hotels (3.99 mi)
- Milford Hotels (17.33 mi)
- Southbridge Hotels (16.34 mi)
- Brimfield Hotels (21.39 mi)
- Shrewsbury Hotels (6.29 mi)
- Sudbury Hotels (22.56 mi)
Recommended cities for you
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Los Angeles Hotels
- Miami Hotels
- San Francisco Hotels
- New Orleans Hotels
- Chicago Hotels
- Fort Lauderdale Hotels
- Boston Hotels
- Honolulu Hotels
- San Diego Hotels
- Washington Hotels
- Toronto Hotels
- Anaheim Hotels
- Atlanta Hotels
- Nashville Hotels
- Seattle Hotels
- Phoenix Hotels
- Myrtle Beach Hotels
Car Rentals Near Main South
- Car rentals in Worcester
- Car rentals in Sturbridge
- Car rentals in Marlborough
- Car rentals in Framingham
- Car rentals in Westborough
- Car rentals in Leominster
- Car rentals in Auburn
- Car rentals in Milford
- Car rentals in Southbridge
- Car rentals in Brimfield
- Car rentals in Shrewsbury
- Car rentals in Sudbury
- Car rentals in Hopkinton
- Car rentals in Fiskdale
- Car rentals in Hudson
- Car rentals in Harvard