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Hotels in Advance

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Tonight Jan 11 - Jan 12Next weekend Jan 17 - Jan 19

Choose from 101 Advance Hotel Deals

Private Getaway on 270 Acres w/ Lake: Swim & Canoe
Private Getaway on 270 Acres w/ Lake: Swim & Canoe
2 out of 5
Advance
  • 6 hours drive from Mississippi River
Stay at this cottage in Advance. Enjoy free parking, a pool table, and air conditioning.
Private Getaway on 270 Acres w/ Lake: Swim & Canoe
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $114 per night from Feb 10 to Feb 11
$114
includes taxes & fees
Feb 10 - Feb 11
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,001 reviews)
"very good, nice location"

Reviewed on Jan 9, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $107 per night from Jan 15 to Jan 16
$107
includes taxes & fees
Jan 15 - Jan 16
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (869 reviews)
"Just remodeled"

Reviewed on Jan 9, 2025

Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $71 per night from Jan 20 to Jan 21
$71
includes taxes & fees
Jan 20 - Jan 21
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
Reliable comfort
"Pear Trees are always nice hotels. Beds are great and room/bathroom clean."

Reviewed on Jan 4, 2025

Pear Tree Inn Cape Girardeau West
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $112 per night from Jan 15 to Jan 16
$112
includes taxes & fees
Jan 15 - Jan 16
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
"The property was close to where we was visiting our family at the staff was friendly and the room was clean there was many options of shopping and dinning close to hotel to choose from... over we would definitely stay agian there andbit will bebour go to when we travel to visit family"

Reviewed on Jan 2, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Candlewood Suites Cape Girardeau, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $89 per night from Jan 16 to Jan 17
$89
includes taxes & fees
Jan 16 - Jan 17
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (713 reviews)
"Loved it"

Reviewed on Jan 6, 2025

Candlewood Suites Cape Girardeau, an IHG Hotel
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
2.5 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
  • 6 hours drive from Mississippi River
The price is $85 per night from Jan 23 to Jan 24
$85
includes taxes & fees
Jan 23 - Jan 24
Book a stay at this business-friendly hotel in Jackson. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (488 reviews)
"Coffee pot was really slow"

Reviewed on Jan 4, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $66 per night from Jan 23 to Jan 24
$66
includes taxes & fees
Jan 23 - Jan 24
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,001 reviews)
"I stayed one night on my travels and the staff was friendly, room was clean, and there are a lot of dining options in the area."

Reviewed on Jan 8, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
The Riverview
The Riverview
3.5 out of 5
777 Main St, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $106 per night from Jan 27 to Jan 28
$106
includes taxes & fees
Jan 27 - Jan 28
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
9.2/10 Wonderful! (120 reviews)
"Great property! Really enjoyed the wonderful location and the staff was very helpful."

Reviewed on Jan 3, 2025

The Riverview
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $137 per night from Jan 26 to Jan 27
$137
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (393 reviews)
"Beautiful historic preservation"

Reviewed on Jan 2, 2025

Courtyard by Marriott Cape Girardeau Downtown
Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $69 per night from Feb 9 to Feb 10
$69
includes taxes & fees
Feb 9 - Feb 10
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (531 reviews)
"Good stay.quick overnight midway through a road trip.. 4 pillows per bed and quality sheets and bedding. Contentinal breakfast and decent coffee. Most importantly it was nice and clean."

Reviewed on Jan 7, 2025

Quality Inn
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 out of 5
433 CAPE WEST CROSSINGS, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $100 per night from Jan 16 to Jan 17
$100
includes taxes & fees
Jan 16 - Jan 17
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
9.2/10 Wonderful! (67 reviews)
"This hotel is very nice. It is very close to everything. People are very helpful and friendly. The breakfast was delicious. Would stay again."

Reviewed on Jan 7, 2025

Fairfield Inn & Suites by Marriott Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Advance

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Advance.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Advance’s 101 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $66. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Advance hotel deals at the last minute.

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Frequently Asked Questions About Advance hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Advance for as low as $66.

How many hotels are there in Advance?

With over 101 hotels in Advance, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $66.

How to find cheap car rentals in Advance?

Finding a cheap car rental deal in Advance is as easy as scoring cheap hotels in Advance. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.