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Grimes

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Grimes Flights as Low as $58

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Mar 25 - Sat, Mar 28
DEN
Denver Intl.
DSM
Des Moines Intl.
$58 Roundtrip, found 11 hours ago
$58
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Wed, Mar 25 from Denver Intl. to Des Moines Intl., returning Sat, Mar 28, priced at $58 found 11 hours ago
Frontier Airlines
Sat, Mar 14 - Sat, Mar 21
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$98 Roundtrip, found 13 hours ago
$98
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Sat, Mar 14 from Sky Harbor Intl. to Des Moines Intl., returning Sat, Mar 21, priced at $98 found 13 hours ago
Frontier Airlines
Wed, Mar 11 - Tue, Mar 17
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$175 Roundtrip, found 5 days ago
$175
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, Mar 11 from Charlotte-Douglas Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $175 found 5 days ago
Frontier Airlines
Thu, Apr 23 - Fri, May 15
DTW
Detroit Metropolitan Wayne County
DSM
Des Moines Intl.
$191 Roundtrip, found 1 day ago
$191
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Apr 23 from Detroit Metropolitan Wayne County to Des Moines Intl., returning Fri, May 15, priced at $191 found 1 day ago
Frontier Airlines
Wed, Mar 25 - Mon, Apr 6
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$223 Roundtrip, found 1 day ago
$223
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Mar 25 from Los Angeles Intl. to Des Moines Intl., returning Mon, Apr 6, priced at $223 found 1 day ago
Bargain Flight
Sat, Mar 14 - Sat, Mar 28
BNA
Nashville Intl.
DSM
Des Moines Intl.
$239 Roundtrip, found 1 day ago
$239
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sat, Mar 14 from Nashville Intl. to Des Moines Intl., returning Sat, Mar 28, priced at $239 found 1 day ago
American Airlines
Wed, Apr 1 - Tue, Apr 14
CRW
Yeager
DSM
Des Moines Intl.
$258 Roundtrip, found 2 days ago
$258
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Apr 1 from Yeager to Des Moines Intl., returning Tue, Apr 14, priced at $258 found 2 days ago
Bargain Flight
Sat, Aug 15 - Tue, Aug 18
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sat, Aug 15 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Tue, Aug 18, priced at $259 found 1 day ago
Frontier Airlines
Mon, Feb 23 - Tue, Mar 10
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$260 Roundtrip, found 2 days ago
$260
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Feb 23 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Tue, Mar 10, priced at $260 found 2 days ago
Frontier Airlines
Mon, Mar 2 - Fri, Mar 6
SFO
San Francisco Intl.
DSM
Des Moines Intl.
$261 Roundtrip, found 1 day ago
$261
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Mar 2 from San Francisco Intl. to Des Moines Intl., returning Fri, Mar 6, priced at $261 found 1 day ago
Delta
Sat, Mar 14 - Wed, Mar 25
ABE
Lehigh Valley Intl.
DSM
Des Moines Intl.
$272 Roundtrip, found 1 hour ago
$272
Roundtrip
found 1 hour ago
Select Delta flight, departing Sat, Mar 14 from Lehigh Valley Intl. to Des Moines Intl., returning Wed, Mar 25, priced at $272 found 1 hour ago
American Airlines
Mon, Mar 16 - Tue, Mar 24
CMH
John Glenn Columbus Intl.
DSM
Des Moines Intl.
$278 Roundtrip, found 15 hours ago
$278
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Mon, Mar 16 from John Glenn Columbus Intl. to Des Moines Intl., returning Tue, Mar 24, priced at $278 found 15 hours ago
Delta
Tue, Jul 28 - Sat, Aug 8
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jul 28 from Newark Liberty Intl. Airport to Des Moines Intl., returning Sat, Aug 8, priced at $279 found 1 day ago
Bargain Flight
Fri, Feb 27 - Sat, Mar 7
SMF
Sacramento Intl.
DSM
Des Moines Intl.
$280 Roundtrip, found 1 day ago
$280
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Feb 27 from Sacramento Intl. to Des Moines Intl., returning Sat, Mar 7, priced at $280 found 1 day ago
American Airlines
Mon, Mar 16 - Tue, Mar 17
BOS
Logan Intl.
DSM
Des Moines Intl.
$321 Roundtrip, found 5 days ago
$321
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Mar 16 from Logan Intl. to Des Moines Intl., returning Tue, Mar 17, priced at $321 found 5 days ago
American Airlines
Fri, May 8 - Sat, May 16
ABQ
Albuquerque Intl. Sunport
DSM
Des Moines Intl.
$352 Roundtrip, found 1 day ago
$352
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 8 from Albuquerque Intl. Sunport to Des Moines Intl., returning Sat, May 16, priced at $352 found 1 day ago

Cheap Flights to Grimes

Fall in love at first flight with your vacation to Grimes by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Grimes on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Grimes, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Grimes

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Grimes with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Grimes?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Grimes are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Grimes?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Grimes.

What airport is best to fly into Grimes?

When you’re planning your trip to Grimes, convenience is the name of the game. Luckily, Grimes Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Grimes must-do list.

How much are flights to Grimes?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Grimes on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $58, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Grimes?

The trick to saving a stack of cash on your flight to Grimes? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $58 right now, why wait?

Grimes Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$58

Last Minute Hotel Deals in Grimes

Tru By Hilton Grimes Des Moines

Tru By Hilton Grimes Des Moines

2.5 out of 5
701 NE Gateway Drive Grimes IA
Stay at this hotel in Grimes. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pole Position Raceway and Sky Zone Indoor Trampoline Park ...
9.2/10 Wonderful! (34 reviews)
Nice new, clean rooms with courteous staff.

Reviewed on Feb 15, 2026

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Tru By Hilton Grimes Des Moines
Red Lion Inn & Suites Grimes

Red Lion Inn & Suites Grimes

251 Gateway Cir Grimes IA
Book a stay at this business-friendly hotel in Grimes. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (608 reviews)
The staff was super friendly! The room was clean and tidy, and we didn't experience anything negative during our two nights there. Definitely recommend!

Reviewed on Feb 16, 2026

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Red Lion Inn & Suites Grimes
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,085 reviews)
Excellent hotel and service. Great restaurant and speak easy!

Reviewed on Feb 21, 2026

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Hotel Fort Des Moines, Curio Collection by Hilton
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (726 reviews)
Hard to ever catch someone at the front desk. Had to switch rooms after 1 night because the carpet got wet through the wall from the shower. WiFi was totally unreliable (terrible especially for being a conference center). Breakfast was pitiful - worker didn’t show up and there was nobody that knew ...

Reviewed on Feb 20, 2026

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Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2 out of 5
7625 Office Plaza Dr N West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
8.4/10 Very Good! (984 reviews)
Hotel was accomodating and welcoming...3 or 4 staff changes and still courteous. Definitely will be staying there again in the future!!

Reviewed on Feb 19, 2026

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Sonesta Simply Suites Des Moines
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,008 reviews)
Room was very clean and spacious the staff was wonderful and very caring!

Reviewed on Feb 18, 2026

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Home2 Suites by Hilton Des Moines at Drake University
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.8/10 Exceptional! (1,045 reviews)
Staff were helpful and breakfast was wonderful. Everything was very clean and beautiful.

Reviewed on Feb 20, 2026

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Des Lux Hotel
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,838 reviews)
Water poured from the light fixture in the bathroom. Room above us was having bath tub draining issues. The rest of the hotel is outdated and falling apart. The pictures on line are 20+ years old. I don’t recommend but our room was clean for the most part.

Reviewed on Feb 16, 2026

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Stoney Creek Hotel Des Moines - Johnston
See all 837 properties in Grimes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.