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Grimes

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Grimes Flights as Low as $105

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Sep 11 - Fri, Sep 12
DEN
Denver Intl.
DSM
Des Moines Intl.
$105 Roundtrip, found 6 days ago
$105
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Sep 11 from Denver Intl. to Des Moines Intl., returning Fri, Sep 12, priced at $105 found 6 days ago
Frontier Airlines
Fri, Sep 12 - Fri, Sep 19
DEN
Denver Intl.
DSM
Des Moines Intl.
$120 Roundtrip, found 3 days ago
$120
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Sep 12 from Denver Intl. to Des Moines Intl., returning Fri, Sep 19, priced at $120 found 3 days ago
Frontier Airlines
Fri, Sep 12 - Mon, Sep 15
DEN
Denver Intl.
DSM
Des Moines Intl.
$121 Roundtrip, found 3 days ago
$121
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Sep 12 from Denver Intl. to Des Moines Intl., returning Mon, Sep 15, priced at $121 found 3 days ago
Frontier Airlines
Thu, Sep 11 - Fri, Sep 19
DEN
Denver Intl.
DSM
Des Moines Intl.
$123 Roundtrip, found 3 days ago
$123
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Sep 11 from Denver Intl. to Des Moines Intl., returning Fri, Sep 19, priced at $123 found 3 days ago
Frontier Airlines
Mon, Sep 15 - Fri, Sep 19
DEN
Denver Intl.
DSM
Des Moines Intl.
$124 Roundtrip, found 3 days ago
$124
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Sep 15 from Denver Intl. to Des Moines Intl., returning Fri, Sep 19, priced at $124 found 3 days ago
Frontier Airlines
Thu, Sep 11 - Fri, Sep 12
DEN
Denver Intl.
DSM
Des Moines Intl.
$128 Roundtrip, found 6 days ago
$128
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Sep 11 from Denver Intl. to Des Moines Intl., returning Fri, Sep 12, priced at $128 found 6 days ago
United
Thu, Sep 11 - Fri, Sep 12
DEN
Denver Intl.
DSM
Des Moines Intl.
$140 Roundtrip, found 6 days ago
$140
Roundtrip
found 6 days ago
Select United flight, departing Thu, Sep 11 from Denver Intl. to Des Moines Intl., returning Fri, Sep 12, priced at $140 found 6 days ago
Frontier Airlines
Fri, Sep 12 - Thu, Sep 18
DEN
Denver Intl.
DSM
Des Moines Intl.
$144 Roundtrip, found 3 days ago
$144
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Sep 12 from Denver Intl. to Des Moines Intl., returning Thu, Sep 18, priced at $144 found 3 days ago
Frontier Airlines
Thu, Sep 11 - Thu, Sep 18
DEN
Denver Intl.
DSM
Des Moines Intl.
$147 Roundtrip, found 3 days ago
$147
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Sep 11 from Denver Intl. to Des Moines Intl., returning Thu, Sep 18, priced at $147 found 3 days ago
American Airlines
Wed, Sep 24 - Wed, Oct 8
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$161 Roundtrip, found 2 days ago
$161
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Sep 24 from Sky Harbor Intl. to Des Moines Intl., returning Wed, Oct 8, priced at $161 found 2 days ago
Delta
Sat, Sep 13 - Sat, Sep 13
DEN
Denver Intl.
DSM
Des Moines Intl.
$191 Roundtrip, found 3 days ago
$191
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Sep 13 from Denver Intl. to Des Moines Intl., returning Sat, Sep 13, priced at $191 found 3 days ago
Delta
Tue, Nov 4 - Tue, Nov 11
VPS
Northwest Florida Regional
DSM
Des Moines Intl.
$207 Roundtrip, found 17 hours ago
$207
Roundtrip
found 17 hours ago
Select Delta flight, departing Tue, Nov 4 from Northwest Florida Regional to Des Moines Intl., returning Tue, Nov 11, priced at $207 found 17 hours ago
Bargain Flight
Wed, Oct 15 - Sat, Oct 25
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$245 Roundtrip, found 18 hours ago
$245
Roundtrip
found 18 hours ago
Select Bargain Flight flight, departing Wed, Oct 15 from Charlotte-Douglas Intl. to Des Moines Intl., returning Sat, Oct 25, priced at $245 found 18 hours ago
Delta
Wed, Oct 22 - Sun, Dec 7
AVL
Asheville Regional
DSM
Des Moines Intl.
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Oct 22 from Asheville Regional to Des Moines Intl., returning Sun, Dec 7, priced at $249 found 1 day ago
Delta
Wed, Oct 22 - Sat, Oct 25
PWM
Portland Intl. Jetport
DSM
Des Moines Intl.
$276 Roundtrip, found 12 hours ago
$276
Roundtrip
found 12 hours ago
Select Delta flight, departing Wed, Oct 22 from Portland Intl. Jetport to Des Moines Intl., returning Sat, Oct 25, priced at $276 found 12 hours ago
United
Sun, Feb 15 - Wed, Feb 18
ABQ
Albuquerque Intl. Sunport
DSM
Des Moines Intl.
$367 Roundtrip, found 11 hours ago
$367
Roundtrip
found 11 hours ago
Select United flight, departing Sun, Feb 15 from Albuquerque Intl. Sunport to Des Moines Intl., returning Wed, Feb 18, priced at $367 found 11 hours ago

Cheap Flights to Grimes

Fall in love at first flight with your vacation to Grimes by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Grimes on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Grimes, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Grimes

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Grimes with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Grimes?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Grimes are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Grimes?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Grimes.

What airport is best to fly into Grimes?

When you’re planning your trip to Grimes, convenience is the name of the game. Luckily, Grimes Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Grimes must-do list.

How much are flights to Grimes?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Grimes on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $105, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Grimes?

The trick to saving a stack of cash on your flight to Grimes? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $105 right now, why wait?

Grimes Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$105

Last Minute Hotel Deals in Grimes

Red Lion Inn & Suites Grimes

Red Lion Inn & Suites Grimes

251 Gateway Cir, Grimes, IA
Book a stay at this business-friendly hotel in Grimes. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.4/10 Good! (554 reviews)
Business trip
"Had a great time. Nice location good view. Comfortable room."

Reviewed on Aug 9, 2025

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Red Lion Inn & Suites Grimes
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,009 reviews)
Beautiful
"This is a beautiful hotel."

Reviewed on Aug 10, 2025

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Hotel Fort Des Moines, Curio Collection by Hilton
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd, Urbandale, IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (545 reviews)
"The pool area was fantastic and loved that they had lifeguards on duty. So much fun! The downside is that the rooms need much updating. It was difficult to find plug ins for phones/electronics. Carpets were worn but all around it was a good place to stay with kids."

Reviewed on Aug 10, 2025

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Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,585 reviews)
"Drain in shower was really slow."

Reviewed on Aug 8, 2025

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Days Inn & Suites by Wyndham Des Moines Airport
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave, Des Moines, IA
Stay at this 3-star hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (1,013 reviews)
"Staff were very nice! Rooms were clean. It was busy the night we stayed, but we had no issues with noise disturbances."

Reviewed on Aug 8, 2025

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Holiday Inn Downtown - Mercy Area by IHG
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.6/10 Good! (510 reviews)
"I'm thinking about the AC had light coming around the frame work"

Reviewed on Aug 10, 2025

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Motel 6 West Des Moines, IA
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,771 reviews)
"This property was priced affordably for families, in a safe neighborhood and we would definitely go back to this property."

Reviewed on Aug 10, 2025

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Stoney Creek Hotel Des Moines - Johnston
Sonesta Essential Des Moines

Sonesta Essential Des Moines

2 out of 5
4755 Merle Hay Road, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,005 reviews)
"Low key, friendly staff, central location near highway and main roads breakfast included helped budget."

Reviewed on Aug 7, 2025

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Sonesta Essential Des Moines
See all 772 properties in Grimes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.