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Louisville

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Louisville Flights as Low as $149

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Mon, May 25 - Mon, Jun 8
DEN
Denver Intl.
TYS
McGhee Tyson
$149 Roundtrip, found 1 day ago
$149
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, May 25 from Denver Intl. to McGhee Tyson, returning Mon, Jun 8, priced at $149 found 1 day ago
American Airlines
Tue, May 26 - Wed, Jun 3
DCA
Ronald Reagan Washington National
TYS
McGhee Tyson
$183 Roundtrip, found 1 day ago
$183
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, May 26 from Ronald Reagan Washington National to McGhee Tyson, returning Wed, Jun 3, priced at $183 found 1 day ago
Delta
Wed, May 20 - Wed, May 27
MCO
Orlando Intl.
TYS
McGhee Tyson
$185 Roundtrip, found 3 days ago
$185
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, May 20 from Orlando Intl. to McGhee Tyson, returning Wed, May 27, priced at $185 found 3 days ago
Delta
Sat, Aug 29 - Wed, Sep 2
ORD
O'Hare Intl.
TYS
McGhee Tyson
$197 Roundtrip, found 3 days ago
$197
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Aug 29 from O'Hare Intl. to McGhee Tyson, returning Wed, Sep 2, priced at $197 found 3 days ago
Delta
Tue, May 26 - Tue, Jun 2
DAL
Love Field
TYS
McGhee Tyson
$201 Roundtrip, found 4 days ago
$201
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, May 26 from Love Field to McGhee Tyson, returning Tue, Jun 2, priced at $201 found 4 days ago
Delta
Tue, Jun 2 - Wed, Jun 3
BWI
Baltimore Washington Intl. Thurgood Marshall
TYS
McGhee Tyson
$203 Roundtrip, found 14 hours ago
$203
Roundtrip
found 14 hours ago
Select Delta flight, departing Tue, Jun 2 from Baltimore Washington Intl. Thurgood Marshall to McGhee Tyson, returning Wed, Jun 3, priced at $203 found 14 hours ago
Frontier Airlines
Sun, May 3 - Fri, May 8
TPA
Tampa Intl.
TYS
McGhee Tyson
$206 Roundtrip, found 2 days ago
$206
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, May 3 from Tampa Intl. to McGhee Tyson, returning Fri, May 8, priced at $206 found 2 days ago
Bargain Flight
Mon, May 25 - Fri, Jun 5
CLE
Hopkins Intl.
TYS
McGhee Tyson
$235 Roundtrip, found 5 days ago
$235
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Mon, May 25 from Hopkins Intl. to McGhee Tyson, returning Fri, Jun 5, priced at $235 found 5 days ago
Bargain Flight
Tue, Nov 10 - Sat, Nov 14
SAT
San Antonio Intl.
TYS
McGhee Tyson
$240 Roundtrip, found 21 hours ago
$240
Roundtrip
found 21 hours ago
Select Bargain Flight flight, departing Tue, Nov 10 from San Antonio Intl. to McGhee Tyson, returning Sat, Nov 14, priced at $240 found 21 hours ago
Delta
Mon, Jul 13 - Tue, Jul 28
ATL
Hartsfield-Jackson Atlanta Intl.
TYS
McGhee Tyson
$259 Roundtrip, found 7 hours ago
$259
Roundtrip
found 7 hours ago
Select Delta flight, departing Mon, Jul 13 from Hartsfield-Jackson Atlanta Intl. to McGhee Tyson, returning Tue, Jul 28, priced at $259 found 7 hours ago
American Airlines
Tue, Sep 22 - Tue, Sep 29
FLL
Fort Lauderdale - Hollywood Intl.
TYS
McGhee Tyson
$265 Roundtrip, found 1 day ago
$265
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 22 from Fort Lauderdale - Hollywood Intl. to McGhee Tyson, returning Tue, Sep 29, priced at $265 found 1 day ago
United
Mon, Aug 10 - Sat, Aug 15
IAH
George Bush Intercontinental
TYS
McGhee Tyson
$269 Roundtrip, found 1 day ago
$269
Roundtrip
found 1 day ago
Select United flight, departing Mon, Aug 10 from George Bush Intercontinental to McGhee Tyson, returning Sat, Aug 15, priced at $269 found 1 day ago
Bargain Flight
Tue, Aug 18 - Fri, Aug 21
MSY
Louis Armstrong New Orleans Intl.
TYS
McGhee Tyson
$271 Roundtrip, found 3 days ago
$271
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Tue, Aug 18 from Louis Armstrong New Orleans Intl. to McGhee Tyson, returning Fri, Aug 21, priced at $271 found 3 days ago
Delta
Wed, May 13 - Wed, May 20
BOS
Logan Intl.
TYS
McGhee Tyson
$278 Roundtrip, found 4 days ago
$278
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, May 13 from Logan Intl. to McGhee Tyson, returning Wed, May 20, priced at $278 found 4 days ago
Bargain Flight
Wed, Apr 29 - Sat, May 2
ABQ
Albuquerque Intl. Sunport
TYS
McGhee Tyson
$312 Roundtrip, found 10 hours ago
$312
Roundtrip
found 10 hours ago
Select Bargain Flight flight, departing Wed, Apr 29 from Albuquerque Intl. Sunport to McGhee Tyson, returning Sat, May 2, priced at $312 found 10 hours ago
Frontier Airlines
Mon, May 18 - Mon, May 25
MIA
Miami Intl.
TYS
McGhee Tyson
$352 Roundtrip, found 1 day ago
$352
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, May 18 from Miami Intl. to McGhee Tyson, returning Mon, May 25, priced at $352 found 1 day ago

Cheap Flights to Louisville

Fall in love at first flight with your vacation to Louisville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Louisville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Louisville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Louisville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Louisville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TYS airport.

What is the cheapest month to fly to Louisville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Louisville are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Louisville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 12 to choose from for your flight to Louisville.

What airport is best to fly into Louisville?

When you’re planning your trip to Louisville, convenience is the name of the game. Luckily, Louisville McGhee Tyson Airport is nearby so you can deplane and get going on checking off everything on your Louisville must-do list.

How much are flights to Louisville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Louisville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $149, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Louisville?

The trick to saving a stack of cash on your flight to Louisville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $149 right now, why wait?

Louisville Flight Information
Destination airport
McGhee Tyson
Destination airport IATA code
TYS
Roundtrip price
$148

Last Minute Hotel Deals in Louisville

Comfort Inn & Suites Knoxville West

Comfort Inn & Suites Knoxville West

2.5 out of 5
7737 Kingston Pike Knoxville TN
Book a stay at this business-friendly hotel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,004 reviews)
This hotel needs a renovation. Dark, dirty, musky. The lighting is bad, ventilation on bathroom non existent. Breakfast was not good either or visible - we weren’t sure where it was and no staff told us.

Reviewed on Apr 27, 2026

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Comfort Inn & Suites Knoxville West
Hilton Knoxville

Hilton Knoxville

3.5 out of 5
501 W Church Ave Knoxville TN
Book a stay at this business-friendly hotel in Knoxville. Enjoy free WiFi, an outdoor pool, and room service. Our guests praise the restaurant and the helpful ...
8.6/10 Excellent! (1,967 reviews)
The property was in a central location to downtown. The room was very clean. Even with the construction, it was not a major disruption to our visit. Only issues we had was elevators were not working properly. On Saturday evening there were 2 of the 3 working and by Sunday morning during checkout, ...

Reviewed on Apr 27, 2026

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Hilton Knoxville
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,855 reviews)
elevator was broken. bathrooms were in rough shape. no soap, provided only body wash to wash hands in bathroom. linens and towels were clean.

Reviewed on Apr 27, 2026

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La Quinta Inn & Suites by Wyndham Knoxville Airport
THE TENNESSEAN Hotel

THE TENNESSEAN Hotel

4 out of 5
531 Henley Street Knoxville TN
Book a stay at this luxury hotel in Knoxville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,006 reviews)
Beautiful hotel. Rooms were very clean and modern.

Reviewed on Apr 25, 2026

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THE TENNESSEAN Hotel
Hyatt Place Knoxville Downtown

Hyatt Place Knoxville Downtown

3 out of 5
530 S Gay St Knoxville TN
Book a stay at this business-friendly hotel in Knoxville. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the bar ...
9.4/10 Exceptional! (1,007 reviews)
Location to downtown is great. Easy walking to Convention Center or Market Square. The staff was very helpful and friendly.

Reviewed on Apr 27, 2026

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Hyatt Place Knoxville Downtown
Americas Best Value Inn - Knoxville East

Americas Best Value Inn - Knoxville East

2.5 out of 5
1550 Cracker Barrel Ln Knoxville TN
Stay at this motel in Knoxville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,011 reviews)
The room was class, I liked the fact that the shampoo, conditioner, body wash, & hand soap were in a container and all you had to do was push in the dispenser to dispense the soaps out.

Reviewed on Apr 26, 2026

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Americas Best Value Inn - Knoxville East
Days Inn by Wyndham Knoxville North

Days Inn by Wyndham Knoxville North

2.5 out of 5
114 Dante Rd Knoxville TN
Book a stay at this business-friendly motel in Knoxville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (681 reviews)
The chair in the room was absolutely disgusting (I have a picture, but cannot post here), and the toilet seat had nasty stains all over it!! Sink did not drain, place was very noisy and you can literally see day light through the door!! Would not recommend this place…

Reviewed on Apr 27, 2026

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Days Inn by Wyndham Knoxville North
WoodSpring Suites Knoxville West

WoodSpring Suites Knoxville West

2.5 out of 5
320 North Gallaher View Rd NW Knoxville TN
Book a stay at this business-friendly hotel in Knoxville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.4/10 Very Good! (647 reviews)
The staff was great. We stayed 3 nights. It was great for our purpose. Lots of restaurants available. Starbucks close by. Walmart across the street. Only ten minutes from the tennova med center. Loved the kitchenette area.

Reviewed on Apr 22, 2026

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WoodSpring Suites Knoxville West
See all 4,538 properties in Louisville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.