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South Carolina Midlands

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South Carolina Midlands Flights as Low as $58

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Feb 10 - Tue, Feb 10
PHL
Philadelphia Intl.
CLT
Charlotte-Douglas Intl.
$58 Roundtrip, found 2 hours ago
$58
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Tue, Feb 10 from Philadelphia Intl. to Charlotte-Douglas Intl., returning Tue, Feb 10, priced at $58 found 2 hours ago
Frontier Airlines
Mon, Feb 23 - Mon, Mar 2
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$109 Roundtrip, found 2 days ago
$109
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Mon, Feb 23 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Mon, Mar 2, priced at $109 found 2 days ago
Spirit Airlines
Tue, Feb 24 - Thu, Feb 26
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$119 Roundtrip, found 3 days ago
$119
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, Feb 24 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Thu, Feb 26, priced at $119 found 3 days ago
Frontier Airlines
Sat, Feb 21 - Wed, Feb 25
TTN
Mercer
CLT
Charlotte-Douglas Intl.
$130 Roundtrip, found 2 hours ago
$130
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Sat, Feb 21 from Mercer to Charlotte-Douglas Intl., returning Wed, Feb 25, priced at $130 found 2 hours ago
Delta
Mon, Feb 23 - Tue, Mar 3
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$139 Roundtrip, found 6 days ago
$139
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Feb 23 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Tue, Mar 3, priced at $139 found 6 days ago
American Airlines
Wed, Feb 25 - Wed, Mar 4
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$143 Roundtrip, found 1 day ago
$143
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 25 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Wed, Mar 4, priced at $143 found 1 day ago
Spirit Airlines
Mon, Apr 20 - Tue, Apr 28
BOS
Logan Intl.
CLT
Charlotte-Douglas Intl.
$171 Roundtrip, found 2 days ago
$171
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Mon, Apr 20 from Logan Intl. to Charlotte-Douglas Intl., returning Tue, Apr 28, priced at $171 found 2 days ago
Frontier Airlines
Wed, Mar 4 - Mon, Mar 9
PHX
Sky Harbor Intl.
CLT
Charlotte-Douglas Intl.
$199 Roundtrip, found 3 days ago
$199
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Mar 4 from Sky Harbor Intl. to Charlotte-Douglas Intl., returning Mon, Mar 9, priced at $199 found 3 days ago
American Airlines
Wed, Mar 18 - Tue, Mar 24
BOS
Logan Intl.
CAE
Columbia Metropolitan
$213 Roundtrip, found 2 days ago
$213
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Mar 18 from Logan Intl. to Columbia Metropolitan, returning Tue, Mar 24, priced at $213 found 2 days ago
Bargain Flight
Sat, Jun 13 - Sat, Jun 20
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$213 Roundtrip, found 4 days ago
$213
Roundtrip
found 4 days ago
Select Bargain Flight flight, departing Sat, Jun 13 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Sat, Jun 20, priced at $213 found 4 days ago
American Airlines
Thu, Apr 16 - Tue, Apr 21
BOS
Logan Intl.
AGS
Augusta Regional
$254 Roundtrip, just found
$254
Roundtrip
just found
Select American Airlines flight, departing Thu, Apr 16 from Logan Intl. to Augusta Regional, returning Tue, Apr 21, priced at $254 just found
American Airlines
Tue, Feb 10 - Wed, Feb 18
PHL
Philadelphia Intl.
AGS
Augusta Regional
$280 Roundtrip, just found
$280
Roundtrip
just found
Select American Airlines flight, departing Tue, Feb 10 from Philadelphia Intl. to Augusta Regional, returning Wed, Feb 18, priced at $280 just found
American Airlines
Wed, Mar 11 - Tue, Mar 17
PHX
Sky Harbor Intl.
AGS
Augusta Regional
$308 Roundtrip, just found
$308
Roundtrip
just found
Select American Airlines flight, departing Wed, Mar 11 from Sky Harbor Intl. to Augusta Regional, returning Tue, Mar 17, priced at $308 just found
Delta
Wed, Feb 25 - Mon, Mar 2
PHX
Sky Harbor Intl.
CAE
Columbia Metropolitan
$313 Roundtrip, found 4 days ago
$313
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Feb 25 from Sky Harbor Intl. to Columbia Metropolitan, returning Mon, Mar 2, priced at $313 found 4 days ago
American Airlines
Wed, Feb 25 - Sat, Feb 28
DTW
Detroit Metropolitan Wayne County
AGS
Augusta Regional
$337 Roundtrip, just found
$337
Roundtrip
just found
Select American Airlines flight, departing Wed, Feb 25 from Detroit Metropolitan Wayne County to Augusta Regional, returning Sat, Feb 28, priced at $337 just found
Delta
Wed, Mar 25 - Tue, Mar 31
PHL
Philadelphia Intl.
CAE
Columbia Metropolitan
$347 Roundtrip, found 1 day ago
$347
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Mar 25 from Philadelphia Intl. to Columbia Metropolitan, returning Tue, Mar 31, priced at $347 found 1 day ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $58, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $58 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$58

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,952 reviews)
This was one of the best motels that I have stayed in. That's saying a lot. I am retired and had to travel often for my job. I was concerned when I booked the room since the motel is very near an interstate highway. My room in the motel was one of the closest to the highway, and we never heard the ...

Reviewed on Jan 26, 2026

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Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
7.6/10 Good! (1,016 reviews)
Friendly staff and clean room.

Reviewed on Jan 25, 2026

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La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.2/10 Wonderful! (1,002 reviews)
Perfect place to stay when visiting USC

Reviewed on Jan 21, 2026

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Graduate by Hilton Columbia SC
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,250 reviews)
Clean room. Hard to adjust temperature in the room. Conveniently located

Reviewed on Jan 23, 2026

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Park Inn by Radisson Florence, SC
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,001 reviews)
The hotel was amazing. The staff was very nice!

Reviewed on Jan 21, 2026

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Courtyard by Marriott Columbia Downtown at USC
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

2.5 out of 5
211 Lanneau Ct Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,021 reviews)
Yes

Reviewed on Jan 25, 2026

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Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,191 reviews)
Most comfortable bed I’ve ever slept in .

Reviewed on Jan 21, 2026

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Comfort Inn & Suites Florence Center Area
Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista

3.5 out of 5
1000 Lady Street Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,183 reviews)
Wonderful staff

Reviewed on Jan 21, 2026

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Cambria Hotel Columbia Downtown The Vista
See all 3,135 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and BTM ...
5.4/10 (1,001 reviews)
Easy quick check in. Ok room for the price

Reviewed on Jan 19, 2026

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Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,001 reviews)
Breakfast was great

Reviewed on Jan 23, 2026

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Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
7.8/10 Good! (999 reviews)
Just that the hotel staff were very courteous and provided everything I asked for.

Reviewed on Jan 5, 2026

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Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,005 reviews)
The hotel smelt clean and the staff was top tier. Bed were comfortable and I would definitely stay here again. Felt like I got more than my moneys worth.

Reviewed on Jan 18, 2026

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Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
Spotless room Awesome staff

Reviewed on Jan 11, 2026

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Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,001 reviews)
Room needed painting and updating. Bed was clean, towels and bathroom were fine. TV was just sitting without a stand leaning against the wall. I’m a low maintenance traveler, it met my needs for the night.

Reviewed on Jan 2, 2026

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Clarion Inn Columbia Airport
See all 3,135 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.