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South Carolina Midlands

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South Carolina Midlands Flights as Low as $257

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Fri, Aug 7 - Mon, Aug 10
JFK
John F. Kennedy Intl.
CLT
Charlotte-Douglas Intl.
$257 Roundtrip, found 2 days ago
$257
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Aug 7 from John F. Kennedy Intl. to Charlotte-Douglas Intl., returning Mon, Aug 10, priced at $257 found 2 days ago
American Airlines
Tue, Jul 7 - Wed, Jul 22
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$257 Roundtrip, found 2 days ago
$257
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jul 7 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Wed, Jul 22, priced at $257 found 2 days ago
United
Mon, Aug 10 - Thu, Aug 13
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$257 Roundtrip, found 2 days ago
$257
Roundtrip
found 2 days ago
Select United flight, departing Mon, Aug 10 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Thu, Aug 13, priced at $257 found 2 days ago
United
Sat, Sep 26 - Tue, Sep 29
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$261 Roundtrip, found 5 days ago
$261
Roundtrip
found 5 days ago
Select United flight, departing Sat, Sep 26 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Tue, Sep 29, priced at $261 found 5 days ago
Delta
Mon, Oct 19 - Tue, Oct 27
EWR
Newark Liberty Intl. Airport
AGS
Augusta Regional
$277 Roundtrip, found 5 days ago
$277
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Oct 19 from Newark Liberty Intl. Airport to Augusta Regional, returning Tue, Oct 27, priced at $277 found 5 days ago
American Airlines
Tue, Jul 14 - Sat, Jul 25
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$283 Roundtrip, found 10 hours ago
$283
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Jul 14 from John F. Kennedy Intl. to Florence Regional, returning Sat, Jul 25, priced at $283 found 10 hours ago
Frontier Airlines
Sat, Jun 27 - Thu, Jul 2
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$296 Roundtrip, found 5 days ago
$296
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sat, Jun 27 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Thu, Jul 2, priced at $296 found 5 days ago
United
Wed, Jul 8 - Mon, Jul 27
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$299 Roundtrip, found 6 days ago
$299
Roundtrip
found 6 days ago
Select United flight, departing Wed, Jul 8 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Mon, Jul 27, priced at $299 found 6 days ago
Delta
Thu, Oct 22 - Sun, Oct 25
JFK
John F. Kennedy Intl.
AGS
Augusta Regional
$308 Roundtrip, found 6 days ago
$308
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Oct 22 from John F. Kennedy Intl. to Augusta Regional, returning Sun, Oct 25, priced at $308 found 6 days ago
American Airlines
Wed, Sep 30 - Sun, Oct 4
EWR
Newark Liberty Intl. Airport
FLO
Florence Regional
$344 Roundtrip, found 6 days ago
$344
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Sep 30 from Newark Liberty Intl. Airport to Florence Regional, returning Sun, Oct 4, priced at $344 found 6 days ago
American Airlines
Fri, Jun 19 - Mon, Jun 22
MIA
Miami Intl.
CAE
Columbia Metropolitan
$347 Roundtrip, found 16 hours ago
$347
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Fri, Jun 19 from Miami Intl. to Columbia Metropolitan, returning Mon, Jun 22, priced at $347 found 16 hours ago
Frontier Airlines
Fri, Jun 19 - Sun, Jun 21
MIA
Miami Intl.
CLT
Charlotte-Douglas Intl.
$359 Roundtrip, found 16 hours ago
$359
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Fri, Jun 19 from Miami Intl. to Charlotte-Douglas Intl., returning Sun, Jun 21, priced at $359 found 16 hours ago
JetBlue Airways
Sat, Sep 26 - Tue, Sep 29
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$383 Roundtrip, found 5 days ago
$383
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Sat, Sep 26 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Tue, Sep 29, priced at $383 found 5 days ago
American Airlines
Wed, Jul 8 - Tue, Jul 14
JFK
John F. Kennedy Intl.
CAE
Columbia Metropolitan
$385 Roundtrip, found 6 days ago
$385
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from John F. Kennedy Intl. to Columbia Metropolitan, returning Tue, Jul 14, priced at $385 found 6 days ago
United
Sat, Jun 20 - Tue, Jun 30
LIT
Clinton National Airport
CAE
Columbia Metropolitan
$439 Roundtrip, found 12 hours ago
$439
Roundtrip
found 12 hours ago
Select United flight, departing Sat, Jun 20 from Clinton National Airport to Columbia Metropolitan, returning Tue, Jun 30, priced at $439 found 12 hours ago
American Airlines
Mon, Jun 15 - Mon, Jun 15
LIT
Clinton National Airport
CLT
Charlotte-Douglas Intl.
$980 Roundtrip, found 2 days ago
$980
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jun 15 from Clinton National Airport to Charlotte-Douglas Intl., returning Mon, Jun 15, priced at $980 found 2 days ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $257, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $257 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$257

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (2,088 reviews)
"Nice hotel comfy beds great location. We will be back."

Reviewed on Jun 5, 2026

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Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Palmetto Performing Arts and ...
8/10 Very Good! (1,014 reviews)
"Friendly clean reasonable price"

Reviewed on Jun 5, 2026

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La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.4/10 Exceptional! (688 reviews)
"The hotel was very very clean and the staff were extremely helpful. The free breakfast was also probably one of the better free breakfasts I’ve seen. That being said - it is a minimalist hotel. So in the room, you don’t really have any comforts. No closet very small desk and no coffee maker. Beds ..."

Reviewed on Jun 4, 2026

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Tru By Hilton Columbia Downtown
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,294 reviews)
"The staff was friendly which made check in easier and check out was a smooth transaction. The room was comfy and clean. However, there are some areas of the hotel are already showing some wear already."

Reviewed on Jun 4, 2026

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Park Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (175 reviews)
"The property was clean and the rooms were also clean the bed was very comfortable, and plenty of parking and very a quiet area, will be back!"

Reviewed on Jun 5, 2026

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Quality Inn & Suites Florence Civic Center
Hyatt Place Columbia/Downtown/The Vista

Hyatt Place Columbia/Downtown/The Vista

3 out of 5
819 Gervais Street Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,005 reviews)
"Very clean"

Reviewed on May 29, 2026

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Hyatt Place Columbia/Downtown/The Vista
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,682 reviews)
"This is a hotel that's really a model if the old Howard Johnson motels that if you're over 60 remember well. Not pretty but has a great personality. It's perfectly fine for a night's stay during a long trip. It's clean, safe, comfortable, and fairly priced. If you're looking for luxury (which I'm ..."

Reviewed on Jun 5, 2026

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Howard Johnson by Wyndham Florence
Clarion Pointe Rock Hill Near University

Clarion Pointe Rock Hill Near University

2.5 out of 5
1106 N. Anderson Road Rock Hill SC
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,070 reviews)
"The room was clean and modern. The staff was very accommodating. The facility was very quiet, especially considering that there was a club basketball team staying there as well."

Reviewed on Jun 5, 2026

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Clarion Pointe Rock Hill Near University
See all 3,275 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and BTM ...
5.6/10 (1,003 reviews)
"Place was not clean. There was roaches in the room. Hallways smell like humidity. They Never came to change sheets, trash cans or leave clean towels. Police was there twice. Pool was not open. Not a lot of options for breakfast."

Reviewed on Jun 5, 2026

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Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,002 reviews)
"Everything was wonderful absolutely no complaints."

Reviewed on Jun 4, 2026

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Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8/10 Very Good! (1,003 reviews)
"The staff was extremely helpful and polite."

Reviewed on May 28, 2026

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Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"Air conditioning not good at all. Had set on the lowest setting and was hot a humid in the room the whole time. Very humid in the hallway as well. The shower sounded like it was about to take flight when it was on and the toilet ran literally all night. I’ll just pay the $150 to stay at the Hilton ..."

Reviewed on May 30, 2026

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Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,009 reviews)
"Nice, clean hotel. Ate in the restaurant and that was good, large portions. Staff accommodating and over all a pleasant stay. Used the shuttle to the airport with no issues."

Reviewed on Jun 5, 2026

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Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,006 reviews)
"Hotel is not clean, roaches in the breakfast area, fleas or bugs were in the room, and drug pushers and prostitutes seem to be on the backside hotel. Skip this place if you have kids or family."

Reviewed on Jun 5, 2026

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Clarion Inn Columbia Airport
See all 3,275 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.