Search Cheap Flights to
South Carolina Midlands

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

South Carolina Midlands Flights as Low as $166

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Sun, May 24 - Thu, May 28
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$166 Roundtrip, found 3 days ago
$166
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Sun, May 24 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Thu, May 28, priced at $166 found 3 days ago
Spirit Airlines
Tue, May 12 - Thu, May 21
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$183 Roundtrip, found 4 days ago
$183
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Tue, May 12 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Thu, May 21, priced at $183 found 4 days ago
Spirit Airlines
Sun, May 24 - Thu, May 28
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$185 Roundtrip, found 3 days ago
$185
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Sun, May 24 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Thu, May 28, priced at $185 found 3 days ago
Spirit Airlines
Sat, Jun 27 - Sun, Jun 28
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$193 Roundtrip, found 2 days ago
$193
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Sat, Jun 27 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Sun, Jun 28, priced at $193 found 2 days ago
Bargain Flight
Wed, Aug 19 - Mon, Aug 24
BOS
Logan Intl.
CLT
Charlotte-Douglas Intl.
$195 Roundtrip, found 3 days ago
$195
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Wed, Aug 19 from Logan Intl. to Charlotte-Douglas Intl., returning Mon, Aug 24, priced at $195 found 3 days ago
Frontier Airlines
Wed, Jul 15 - Wed, Aug 5
ONT
Ontario Intl. Airport
CLT
Charlotte-Douglas Intl.
$210 Roundtrip, found 11 hours ago
$210
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Wed, Jul 15 from Ontario Intl. Airport to Charlotte-Douglas Intl., returning Wed, Aug 5, priced at $210 found 11 hours ago
Frontier Airlines
Sat, May 23 - Wed, May 27
SAT
San Antonio Intl.
CLT
Charlotte-Douglas Intl.
$231 Roundtrip, found 5 days ago
$231
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sat, May 23 from San Antonio Intl. to Charlotte-Douglas Intl., returning Wed, May 27, priced at $231 found 5 days ago
Bargain Flight
Sat, May 9 - Tue, May 12
BOS
Logan Intl.
CAE
Columbia Metropolitan
$257 Roundtrip, just found
$257
Roundtrip
just found
Select Bargain Flight flight, departing Sat, May 9 from Logan Intl. to Columbia Metropolitan, returning Tue, May 12, priced at $257 just found
American Airlines
Sat, Aug 29 - Mon, Aug 31
EWR
Newark Liberty Intl. Airport
CLT
Charlotte-Douglas Intl.
$269 Roundtrip, found 1 day ago
$269
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Aug 29 from Newark Liberty Intl. Airport to Charlotte-Douglas Intl., returning Mon, Aug 31, priced at $269 found 1 day ago
United
Sun, May 24 - Mon, Jun 1
EWR
Newark Liberty Intl. Airport
CAE
Columbia Metropolitan
$275 Roundtrip, found 3 days ago
$275
Roundtrip
found 3 days ago
Select United flight, departing Sun, May 24 from Newark Liberty Intl. Airport to Columbia Metropolitan, returning Mon, Jun 1, priced at $275 found 3 days ago
Delta
Tue, Sep 15 - Tue, Sep 22
BOS
Logan Intl.
AGS
Augusta Regional
$277 Roundtrip, found 3 hours ago
$277
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Sep 15 from Logan Intl. to Augusta Regional, returning Tue, Sep 22, priced at $277 found 3 hours ago
Delta
Wed, Jun 17 - Wed, Jun 24
SAT
San Antonio Intl.
AGS
Augusta Regional
$277 Roundtrip, found 3 hours ago
$277
Roundtrip
found 3 hours ago
Select Delta flight, departing Wed, Jun 17 from San Antonio Intl. to Augusta Regional, returning Wed, Jun 24, priced at $277 found 3 hours ago
American Airlines
Tue, Jun 9 - Sat, Jun 20
EWR
Newark Liberty Intl. Airport
AGS
Augusta Regional
$288 Roundtrip, found 19 hours ago
$288
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Jun 9 from Newark Liberty Intl. Airport to Augusta Regional, returning Sat, Jun 20, priced at $288 found 19 hours ago
Delta
Wed, Jul 8 - Tue, Jul 28
ONT
Ontario Intl. Airport
CAE
Columbia Metropolitan
$351 Roundtrip, found 1 day ago
$351
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jul 8 from Ontario Intl. Airport to Columbia Metropolitan, returning Tue, Jul 28, priced at $351 found 1 day ago
Delta
Sat, May 16 - Sat, May 23
ONT
Ontario Intl. Airport
AGS
Augusta Regional
$488 Roundtrip, found 1 day ago
$488
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, May 16 from Ontario Intl. Airport to Augusta Regional, returning Sat, May 23, priced at $488 found 1 day ago
Alaska Airlines
Wed, Jul 8 - Tue, Jul 28
ONT
Ontario Intl. Airport
CAE
Columbia Metropolitan
$659 Roundtrip, found 1 day ago
$659
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Wed, Jul 8 from Ontario Intl. Airport to Columbia Metropolitan, returning Tue, Jul 28, priced at $659 found 1 day ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $166, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $166 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$166

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,036 reviews)
The rooms were very clean with all about and put together also the staff was very polite to me and my family and the breakfast bar looked it fabulous the only thing that I wasn't pleased about is that they did not have complimentary breakfast that you didn't have to pay for wasn't included in this ...

Reviewed on May 2, 2026

Get rates
Hilton Garden Inn Columbia/Harbison
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,650 reviews)
Wonderful surprise. Wish there were blackout curtains tho.

Reviewed on May 2, 2026

Get rates
Howard Johnson by Wyndham Florence
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,059 reviews)
the front desk person was very helpful

Reviewed on May 2, 2026

Get rates
Sleep Inn Columbia
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,257 reviews)
Hall carpets needed cleaned. Bathroom door will not close. Fresh donuts would be nice.

Reviewed on May 2, 2026

Get rates
Park Inn by Radisson Florence, SC
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,005 reviews)
Clean room, nice feel to the room. Well lit parking. Easy to walk to grab dinner.

Reviewed on May 2, 2026

Get rates
Courtyard by Marriott Columbia Downtown at USC
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
8/10 Very Good! (1,006 reviews)
The air conditioner in my room was a wall thermostat that was set at 75. When you tried to turn it down it went back to 75. Called front desk and he was clueless on what to do. It was so muggy it was miserable. For the price of two nights I would not stay again. I will say the rooms were very ...

Reviewed on May 1, 2026

Get rates
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia, SC

2.5 out of 5
220 E Exchange Blvd Columbia SC
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.8/10 Good! (1,096 reviews)
The room was clean and the breakfast was tasty. But the STAR of the place was the front desk clerk named Tre ( i am not sure if the spelling). She went above and beyond. She was very friendly, accommodating, helpful, humorous and made the stay more than worthwhile.

Reviewed on May 2, 2026

Get rates
Country Inn & Suites by Radisson, Columbia, SC
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.4/10 Exceptional! (633 reviews)
If they can sort out the parking situation, this hotel would be idea. I don’t understand why we have to pay to park in their DEDICATED parking LOT (not garage). Other than that, very clean, the food and beverages from the bar was great and staff is friendly.

Reviewed on May 2, 2026

Get rates
Tru By Hilton Columbia Downtown
See all 3,282 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and BTM ...
5.6/10 (1,004 reviews)
I hated this place…let me count the ways…the floors were dirty…they were out of soap and toilet tissue… there was intermittent wi/fi connection so it was almost impossible to watch tv because it just kept buffering. The outside grounds were littered and not cleaned up during my stay. The breakfast ...

Reviewed on May 2, 2026

Get rates
Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,001 reviews)
The room was clean, spacious, & comfortable. Airport shuttle was right on time, but I was too early for breakfast.

Reviewed on May 1, 2026

Get rates
Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8/10 Very Good! (1,001 reviews)
Needs a little TLC... but overall it was a okay.

Reviewed on Apr 27, 2026

Get rates
Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
Room was clean, breakfast was great, parking was easy and safe

Reviewed on Apr 27, 2026

Get rates
Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
The hotel was incredible. The staff was very friendly and nice. Hotel was very clean and if I visit Columbia again I will definitely stay this hotel

Reviewed on May 3, 2026

Get rates
Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,003 reviews)
Place needs to be tore down

Reviewed on May 1, 2026

Get rates
Clarion Inn Columbia Airport
See all 3,282 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.