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South Carolina Midlands

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South Carolina Midlands Flights as Low as $38

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Dec 2 - Sat, Dec 5
FLL
Fort Lauderdale - Hollywood Intl.
CLT
Charlotte-Douglas Intl.
$38 Roundtrip, found 1 day ago
$38
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Dec 2 from Fort Lauderdale - Hollywood Intl. to Charlotte-Douglas Intl., returning Sat, Dec 5, priced at $38 found 1 day ago
JetBlue Airways
Wed, Feb 17 - Wed, Mar 10
FLL
Fort Lauderdale - Hollywood Intl.
CLT
Charlotte-Douglas Intl.
$117 Roundtrip, just found
$117
Roundtrip
just found
Select JetBlue Airways flight, departing Wed, Feb 17 from Fort Lauderdale - Hollywood Intl. to Charlotte-Douglas Intl., returning Wed, Mar 10, priced at $117 just found
Frontier Airlines
Wed, Dec 2 - Tue, Dec 15
DTW
Detroit Metropolitan Wayne County
CLT
Charlotte-Douglas Intl.
$140 Roundtrip, found 1 day ago
$140
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Dec 2 from Detroit Metropolitan Wayne County to Charlotte-Douglas Intl., returning Tue, Dec 15, priced at $140 found 1 day ago
American Airlines
Wed, Feb 17 - Wed, Mar 10
FLL
Fort Lauderdale - Hollywood Intl.
CLT
Charlotte-Douglas Intl.
$147 Roundtrip, just found
$147
Roundtrip
just found
Select American Airlines flight, departing Wed, Feb 17 from Fort Lauderdale - Hollywood Intl. to Charlotte-Douglas Intl., returning Wed, Mar 10, priced at $147 just found
Frontier Airlines
Tue, Dec 1 - Wed, Dec 16
PHL
Philadelphia Intl.
CLT
Charlotte-Douglas Intl.
$155 Roundtrip, found 1 hour ago
$155
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Tue, Dec 1 from Philadelphia Intl. to Charlotte-Douglas Intl., returning Wed, Dec 16, priced at $155 found 1 hour ago
Frontier Airlines
Tue, Dec 1 - Wed, Dec 16
TTN
Mercer
CLT
Charlotte-Douglas Intl.
$186 Roundtrip, found 5 days ago
$186
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Tue, Dec 1 from Mercer to Charlotte-Douglas Intl., returning Wed, Dec 16, priced at $186 found 5 days ago
Allegiant Air
Fri, Nov 6 - Mon, Nov 9
FLL
Fort Lauderdale - Hollywood Intl.
USA
Concord Regional
$186 Roundtrip, found 5 hours ago
$186
Roundtrip
found 5 hours ago
Select Allegiant Air flight, departing Fri, Nov 6 from Fort Lauderdale - Hollywood Intl. to Concord Regional, returning Mon, Nov 9, priced at $186 found 5 hours ago
Frontier Airlines
Wed, Nov 25 - Wed, Dec 2
SAT
San Antonio Intl.
CLT
Charlotte-Douglas Intl.
$210 Roundtrip, found 3 hours ago
$210
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Wed, Nov 25 from San Antonio Intl. to Charlotte-Douglas Intl., returning Wed, Dec 2, priced at $210 found 3 hours ago
Delta
Tue, Jan 26 - Tue, Feb 2
FLL
Fort Lauderdale - Hollywood Intl.
CAE
Columbia Metropolitan
$215 Roundtrip, found 1 hour ago
$215
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Jan 26 from Fort Lauderdale - Hollywood Intl. to Columbia Metropolitan, returning Tue, Feb 2, priced at $215 found 1 hour ago
Bargain Flight
Wed, Nov 11 - Wed, Nov 25
PHL
Philadelphia Intl.
CAE
Columbia Metropolitan
$265 Roundtrip, found 4 hours ago
$265
Roundtrip
found 4 hours ago
Select Bargain Flight flight, departing Wed, Nov 11 from Philadelphia Intl. to Columbia Metropolitan, returning Wed, Nov 25, priced at $265 found 4 hours ago
Bargain Flight
Sat, Nov 7 - Tue, Nov 10
DTW
Detroit Metropolitan Wayne County
CAE
Columbia Metropolitan
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Sat, Nov 7 from Detroit Metropolitan Wayne County to Columbia Metropolitan, returning Tue, Nov 10, priced at $279 found 1 day ago
American Airlines
Tue, Dec 1 - Thu, Dec 24
FLL
Fort Lauderdale - Hollywood Intl.
AGS
Augusta Regional
$336 Roundtrip, found 14 hours ago
$336
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Tue, Dec 1 from Fort Lauderdale - Hollywood Intl. to Augusta Regional, returning Thu, Dec 24, priced at $336 found 14 hours ago
Bargain Flight
Wed, Dec 2 - Wed, Dec 2
SAT
San Antonio Intl.
CAE
Columbia Metropolitan
$360 Roundtrip, found 2 days ago
$360
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Wed, Dec 2 from San Antonio Intl. to Columbia Metropolitan, returning Wed, Dec 2, priced at $360 found 2 days ago
American Airlines
Tue, Nov 17 - Wed, Dec 2
SAT
San Antonio Intl.
AGS
Augusta Regional
$406 Roundtrip, found 1 hour ago
$406
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Nov 17 from San Antonio Intl. to Augusta Regional, returning Wed, Dec 2, priced at $406 found 1 hour ago
American Airlines
Mon, Nov 23 - Wed, Dec 2
SAT
San Antonio Intl.
FLO
Florence Regional
$513 Roundtrip, found 21 hours ago
$513
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Mon, Nov 23 from San Antonio Intl. to Florence Regional, returning Wed, Dec 2, priced at $513 found 21 hours ago
American Airlines
Fri, Nov 27 - Fri, Nov 27
PHL
Philadelphia Intl.
FLO
Florence Regional
$568 Roundtrip, found 1 hour ago
$568
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Fri, Nov 27 from Philadelphia Intl. to Florence Regional, returning Fri, Nov 27, priced at $568 found 1 hour ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in December, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $38, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $38 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$140

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,273 reviews)
"We enjoyed our stay, quite relaxing. Barbara, who just so happen to be doing the audit thewas extraordinary!"

Reviewed on Nov 2, 2026

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Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Williams Brice Stadium and Colonial ...
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La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Sleep Inn Columbia
Clarion Pointe Rock Hill Near University

Clarion Pointe Rock Hill Near University

2.5 out of 5
1106 N. Anderson Road Rock Hill SC
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,069 reviews)
"Property was as described, clean, staff friendly and helpful."

Reviewed on Nov 2, 2026

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Clarion Pointe Rock Hill Near University
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Colonial Life Arena and Riverbanks Zoo and ...
9.4/10 Exceptional! (973 reviews)
"Hotel was clean, room did not have anyplace to put your clothes, had a couple of hangers but no type of dresser. Had a shelf that Im assuming may have been to put things. Room was small with 2 queen beds, but everything was clean."

Reviewed on Nov 2, 2026

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Tru By Hilton Columbia Downtown
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,003 reviews)
"Miss Aimee at the front desk is wonderful!! She makes you feel welcome and addresses any needs you have."

Reviewed on Nov 1, 2026

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Courtyard by Marriott Columbia Downtown at USC
Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone

2.5 out of 5
185 Stoneridge Drive Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,156 reviews)
"This is the 2nd time I booked this hotel in 2 weeks because I loved it so much! Staff is so friendly! Rooms are super clean. Very reasonable price! Breakfast is a nice touch! The river walk is a 3 min drive and it’s awesome! Highly recommend!"

Reviewed on Nov 1, 2026

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Tru By Hilton Columbia Greystone
Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia, SC

2.5 out of 5
220 E Exchange Blvd Columbia SC
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
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Country Inn & Suites by Radisson, Columbia, SC
See all 3,384 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and Colonial ...
Get rates
Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,005 reviews)
"Served its purpose. Clean, safe, super quiet, great little hotel for a quick over night stay while traveling. Will use this place again."

Reviewed on Nov 2, 2026

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Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
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Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"The problem with this hotel is the guests. People were talking and arguing in the parking lot at 4am. Also playing loud music which could be heard through the paper thin walls They need security oitside. Terrible experience would never stay there again"

Reviewed on Oct 31, 2026

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Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,003 reviews)
"Pool is very small. Other than that, it is recommended."

Reviewed on Nov 1, 2026

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Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
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Clarion Inn Columbia Airport
See all 3,384 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.