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South Carolina Midlands

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South Carolina Midlands Flights as Low as $151

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Oct 17 - Mon, Nov 2
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$151 Roundtrip, found 23 hours ago
$151
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Sat, Oct 17 from LaGuardia to Charlotte-Douglas Intl., returning Mon, Nov 2, priced at $151 found 23 hours ago
Frontier Airlines
Tue, Oct 27 - Tue, Nov 10
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$162 Roundtrip, found 13 hours ago
$162
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Tue, Oct 27 from LaGuardia to Charlotte-Douglas Intl., returning Tue, Nov 10, priced at $162 found 13 hours ago
Frontier Airlines
Tue, Nov 3 - Sat, Nov 14
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$163 Roundtrip, found 2 days ago
$163
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Tue, Nov 3 from LaGuardia to Charlotte-Douglas Intl., returning Sat, Nov 14, priced at $163 found 2 days ago
Bargain Flight
Sat, Sep 26 - Sat, Oct 3
LGA
LaGuardia
CLT
Charlotte-Douglas Intl.
$185 Roundtrip, found 13 hours ago
$185
Roundtrip
found 13 hours ago
Select Bargain Flight flight, departing Sat, Sep 26 from LaGuardia to Charlotte-Douglas Intl., returning Sat, Oct 3, priced at $185 found 13 hours ago
Frontier Airlines
Thu, Nov 5 - Sat, Nov 21
DEN
Denver Intl.
CLT
Charlotte-Douglas Intl.
$253 Roundtrip, found 1 day ago
$253
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Nov 5 from Denver Intl. to Charlotte-Douglas Intl., returning Sat, Nov 21, priced at $253 found 1 day ago
Bargain Flight
Wed, Sep 16 - Tue, Sep 22
LGA
LaGuardia
CAE
Columbia Metropolitan
$258 Roundtrip, just found
$258
Roundtrip
just found
Select Bargain Flight flight, departing Wed, Sep 16 from LaGuardia to Columbia Metropolitan, returning Tue, Sep 22, priced at $258 just found
Bargain Flight
Wed, Sep 9 - Sat, Sep 12
ROC
Greater Rochester Intl.
CLT
Charlotte-Douglas Intl.
$263 Roundtrip, found 3 hours ago
$263
Roundtrip
found 3 hours ago
Select Bargain Flight flight, departing Wed, Sep 9 from Greater Rochester Intl. to Charlotte-Douglas Intl., returning Sat, Sep 12, priced at $263 found 3 hours ago
American Airlines
Sat, Nov 14 - Wed, Nov 18
DEN
Denver Intl.
CLT
Charlotte-Douglas Intl.
$270 Roundtrip, found 2 hours ago
$270
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Nov 14 from Denver Intl. to Charlotte-Douglas Intl., returning Wed, Nov 18, priced at $270 found 2 hours ago
Southwest Airlines
Sat, Nov 14 - Wed, Nov 18
DEN
Denver Intl.
CLT
Charlotte-Douglas Intl.
$289 Roundtrip, found 2 hours ago
$289
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Sat, Nov 14 from Denver Intl. to Charlotte-Douglas Intl., returning Wed, Nov 18, priced at $289 found 2 hours ago
Delta
Sat, Nov 14 - Wed, Nov 18
DEN
Denver Intl.
CLT
Charlotte-Douglas Intl.
$290 Roundtrip, found 2 hours ago
$290
Roundtrip
found 2 hours ago
Select Delta flight, departing Sat, Nov 14 from Denver Intl. to Charlotte-Douglas Intl., returning Wed, Nov 18, priced at $290 found 2 hours ago
American Airlines
Tue, Oct 20 - Tue, Oct 27
LGA
LaGuardia
AGS
Augusta Regional
$295 Roundtrip, found 8 hours ago
$295
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Oct 20 from LaGuardia to Augusta Regional, returning Tue, Oct 27, priced at $295 found 8 hours ago
Avelo Airlines
Thu, Sep 10 - Sat, Sep 12
ROC
Greater Rochester Intl.
USA
Concord Regional
$313 Roundtrip, found 5 hours ago
$313
Roundtrip
found 5 hours ago
Select Avelo Airlines flight, departing Thu, Sep 10 from Greater Rochester Intl. to Concord Regional, returning Sat, Sep 12, priced at $313 found 5 hours ago
American Airlines
Sat, Oct 31 - Sat, Nov 7
DEN
Denver Intl.
CAE
Columbia Metropolitan
$336 Roundtrip, found 4 days ago
$336
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 31 from Denver Intl. to Columbia Metropolitan, returning Sat, Nov 7, priced at $336 found 4 days ago
American Airlines
Wed, Sep 30 - Tue, Oct 13
DEN
Denver Intl.
AGS
Augusta Regional
$392 Roundtrip, found 8 hours ago
$392
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Sep 30 from Denver Intl. to Augusta Regional, returning Tue, Oct 13, priced at $392 found 8 hours ago
American Airlines
Tue, Sep 8 - Sat, Sep 12
LGA
LaGuardia
FLO
Florence Regional
$477 Roundtrip, found 17 hours ago
$477
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Tue, Sep 8 from LaGuardia to Florence Regional, returning Sat, Sep 12, priced at $477 found 17 hours ago
Air Canada
Tue, Nov 17 - Mon, Nov 30
ANU
V.C. Bird Intl.
CLT
Charlotte-Douglas Intl.
$515 Roundtrip, found 6 hours ago
$515
Roundtrip
found 6 hours ago
Select Air Canada flight, departing Tue, Nov 17 from V.C. Bird Intl. to Charlotte-Douglas Intl., returning Mon, Nov 30, priced at $515 found 6 hours ago

Cheap Flights to South Carolina Midlands

Fall in love at first flight with your vacation to South Carolina Midlands by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to South Carolina Midlands on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in South Carolina Midlands, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to South Carolina Midlands

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to South Carolina Midlands with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CAE airport.

What is the cheapest month to fly to South Carolina Midlands?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to South Carolina Midlands are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to South Carolina Midlands?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to South Carolina Midlands.

What airport is best to fly into South Carolina Midlands?

When you’re planning your trip to South Carolina Midlands, convenience is the name of the game. Luckily, South Carolina Midlands Columbia Metropolitan Airport is nearby so you can deplane and get going on checking off everything on your South Carolina Midlands must-do list.

How much are flights to South Carolina Midlands?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to South Carolina Midlands on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $151, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to South Carolina Midlands?

The trick to saving a stack of cash on your flight to South Carolina Midlands? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $151 right now, why wait?

South Carolina Midlands Flight Information
Destination airport
Charlotte-Douglas Intl.
Destination airport IATA code
CLT
Roundtrip price
$211

Last Minute Hotel Deals in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,279 reviews)
"Clean room"

Reviewed on Sep 6, 2026

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Hilton Garden Inn Columbia/Harbison
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Quality Inn & Suites Florence Civic Center
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Williams Brice Stadium and Colonial ...
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La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Sleep Inn Columbia
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
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Park Inn by Radisson Florence, SC
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
1539 Horseshoe Dr Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,525 reviews)
"Hotel looks like it use to be a old apartment complex inside. The updated outside and lobby but everything is outdated. From popcorn ceiling, dirty looking tub due to chip paint, smell of wetness in the air. And the the fire/ carbon detectors wrapped in plastic."

Reviewed on Sep 6, 2026

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Wyndham Garden Columbia/Ft. Jackson
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Colonial Life Arena and Riverbanks Zoo and ...
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Tru By Hilton Columbia Downtown
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
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Courtyard by Marriott Columbia Downtown at USC
See all 3,350 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

2.5 out of 5
347 Zimalcrest Drive Columbia SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and Colonial ...
Get rates
Baymont by Wyndham Columbia Northwest
Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
2245 Airport Blvd Cayce SC
Book a stay at this business-friendly hotel in Cayce. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,002 reviews)
"The room was clean the staff was great the breakfast probably could have been better"

Reviewed on Sep 5, 2026

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Country Inn & Suites by Radisson, Columbia Airport, SC
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

4 out of 5
2100 Bush River Road Columbia SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
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Doubletree by Hilton Columbia, SC
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
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Hampton Inn Columbia-I-26 Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
"Everything and everyone was great with service and on point. Breakfast is billed to your room oh and the kitchen staff can cook !!"

Reviewed on Sep 5, 2026

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Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
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Clarion Inn Columbia Airport
See all 3,350 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.