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Hotels in South Carolina Midlands

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Choose from 2839 South Carolina Midlands Hotel Deals

Hilton Garden Inn Columbia/Harbison
Hilton Garden Inn Columbia/Harbison
3 out of 5
434 Columbiana Dr, Columbia, SC
  • 34 min drive from Fort Jackson
The price is $104 per night from Apr 20 to Apr 21
$104
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,412 reviews)
"The staff was friendly and helpful. Did not find anything I didn't like except the Experience I had with the booking company. Trivago is a joke."

Reviewed on Apr 9, 2025

Hilton Garden Inn Columbia/Harbison
Clarion Pointe Near University
Clarion Pointe Near University
2.5 out of 5
1106 N. Anderson Road, Rock Hill, SC
  • 3 hours drive from Fort Jackson
The price is $85 per night from Apr 27 to Apr 28
$85
includes taxes & fees
Apr 27 - Apr 28
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,010 reviews)
"Very friendly staff. I have stayed at this property a few times. Will stay again in the future"

Reviewed on Apr 7, 2025

Clarion Pointe Near University
 La Quinta Inn by Wyndham Columbia NE/Fort Jackson
La Quinta Inn by Wyndham Columbia NE/Fort Jackson
2.5 out of 5
1538 Horseshoe Drive, Columbia, SC
  • 9 min drive from Fort Jackson
The price is $92 per night from Apr 20 to Apr 21
$92
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,274 reviews)
"Property was clean and quiet."

Reviewed on Apr 5, 2025

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center
2.5 out of 5
150 Dunbarton Dr, Florence, SC
  • 3 hours drive from Fort Jackson
The price is $101 per night from Apr 20 to Apr 21
$101
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,170 reviews)
"."

Reviewed on Apr 8, 2025

Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 out of 5
1729 Mandeville Road, Florence, SC
  • 3 hours drive from Fort Jackson
The price is $112 per night from May 4 to May 5
$112
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,017 reviews)
"Good hotel for a quick overnight stay."

Reviewed on Apr 7, 2025

Park Inn by Radisson Florence, SC
Graduate by Hilton Columbia SC
Graduate by Hilton Columbia SC
4 out of 5
1619 Pendleton Street, Columbia, SC
  • 12 min drive from Fort Jackson
The price is $167 per night from Apr 27 to Apr 28
$167
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the bar and ...
9.4/10 Exceptional! (1,000 reviews)
"BEAUTIFUL AND CLEAN HOTEL"

Reviewed on Apr 7, 2025

Graduate by Hilton Columbia SC
Wyndham Garden Columbia/Ft. Jackson
Wyndham Garden Columbia/Ft. Jackson
2.5 out of 5
1539 Horseshoe Dr, Columbia, SC
  • 9 min drive from Fort Jackson
The price is $88 per night from Apr 13 to Apr 14
$88
includes taxes & fees
Apr 13 - Apr 14
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (991 reviews)
"Everything was perfect"

Reviewed on Apr 7, 2025

Wyndham Garden Columbia/Ft. Jackson
Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
  • 3 hours drive from Fort Jackson
The price is $79 per night from Apr 13 to Apr 14
$79
includes taxes & fees
Apr 13 - Apr 14
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,161 reviews)
"Friendly service"

Reviewed on Apr 8, 2025

Howard Johnson by Wyndham Florence
Cambria Hotel Columbia Downtown The Vista
Cambria Hotel Columbia Downtown The Vista
3.5 out of 5
1000 Lady Street, Columbia, SC
  • 14 min drive from Fort Jackson
The price is $140 per night from Apr 20 to Apr 21
$140
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.2/10 Wonderful! (916 reviews)
Worth a Try
"Convenient to Univ. SC and restaurants. Disappointed they don’t offer a complimentary breakfast for the price. Also, surprised at the added $20 to park. Build that into your price."

Reviewed on Apr 7, 2025

Cambria Hotel Columbia Downtown The Vista
Sleep Inn Columbia
Sleep Inn Columbia
2.5 out of 5
1901 Rockland Rd, Columbia, SC
  • 25 min drive from Fort Jackson
The price is $92 per night from May 4 to May 5
$92
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,000 reviews)
Comfortable stay
"Very comfortable room. Spacious, clean. There was no view out the window of our ground floor room, but that didn’t matter for a one-night stopover. Very friendly and helpful night clerk Tom checked us in and responded to all requests in a humorous yet professional way. Only complaints: 1. 2 of the ..."

Reviewed on Apr 8, 2025

Sleep Inn Columbia
Hampton Inn & Suites Columbia Killian Road
Hampton Inn & Suites Columbia Killian Road
2.5 out of 5
1310 Roberts Branch Pkwy, Columbia, SC
  • 20 min drive from Fort Jackson
The price is $122 per night from May 11 to May 12
$122
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,000 reviews)
"So much dining option and next to highway"

Reviewed on Apr 6, 2025

Hampton Inn & Suites Columbia Killian Road
Woodspring Suites Columbia - Irmo
Woodspring Suites Columbia - Irmo
2.5 out of 5
941 Columbiana Dr, Irmo, SC
  • 37 min drive from Fort Jackson
The price is $97 per night from Apr 13 to Apr 14
$97
includes taxes & fees
Apr 13 - Apr 14
Stay at this hotel in Irmo. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Lake Murray and Irmo Community Park are located ...
8.2/10 Very Good! (75 reviews)
"Always need a coffee maker."

Reviewed on Apr 7, 2025

Woodspring Suites Columbia - Irmo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South Carolina Midlands

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $79. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great South Carolina Midlands hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South Carolina Midlands. No matter your reason for visiting South Carolina Midlands, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South Carolina Midlands hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in South Carolina Midlands?

With over 2,839 hotels in South Carolina Midlands, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $79.

How to find cheap car rentals in South Carolina Midlands?

Finding a cheap car rental deal in South Carolina Midlands is as easy as scoring cheap hotels in South Carolina Midlands. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.