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Hotels in South Carolina Midlands

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Choose from 3046 South Carolina Midlands Hotel Deals

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 34 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,858 reviews)
Staff was very attentive when the heater didn't work. They were unable to fix it but they switched my room right away and did not hassle me at all.

Reviewed on Dec 3, 2025

Hilton Garden Inn Columbia/Harbison
Baymont by Wyndham Columbia Fort Jackson

Baymont by Wyndham Columbia Fort Jackson

2.5 out of 5
240 E Exchange Blvd Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
5.6/10 (1,018 reviews)
“Free” breakfast was overpriced. Simple stuff (like no salt & pepper, not to mention other missing items, like a meat offering in the chafing dish next to the scrambled eggs). Not like dish was dirty because it had been emptied. Looked like nothing had ever been in it yet, at 7:45 AM (opened at 6:30). ...

Reviewed on Nov 22, 2025

Baymont by Wyndham Columbia Fort Jackson
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
1539 Horseshoe Dr Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,345 reviews)
Great staff. Literally working non stop

Reviewed on Dec 2, 2025

Wyndham Garden Columbia/Ft. Jackson
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
  • 13 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,005 reviews)
Fast service and great perks!

Reviewed on Nov 29, 2025

Courtyard by Marriott Columbia Downtown at USC
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
7.6/10 Good! (1,017 reviews)
Nice clean and updated room.

Reviewed on Nov 24, 2025

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista

3.5 out of 5
1000 Lady Street Columbia SC
  • 14 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,139 reviews)
Front desk was amazing

Reviewed on Nov 27, 2025

Cambria Hotel Columbia Downtown The Vista
 La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

3 out of 5
1538 Horseshoe Drive Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,770 reviews)
1 of the best hotels I've been to.

Reviewed on Nov 30, 2025

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
  • 3 hours drive from Fort Jackson
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,477 reviews)
Fully recommendable, meeting expectations

Reviewed on Nov 30, 2025

Howard Johnson by Wyndham Florence
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
  • 25 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,000 reviews)
Fast Check In

Reviewed on Nov 30, 2025

Sleep Inn Columbia
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street Columbia SC
  • 12 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,027 reviews)
Every staff member was friendly and helpful. There are lots of cool old charm features from the original property.

Reviewed on Nov 30, 2025

Graduate by Hilton Columbia SC
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
  • 15 min drive from Fort Jackson
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Riverbanks Zoo and Garden and EdVenture ...
9.2/10 Wonderful! (427 reviews)
Wonderful staff, very clean room and great wings.

Reviewed on Nov 30, 2025

Tru By Hilton Columbia Downtown
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
  • 3 hours drive from Fort Jackson
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,209 reviews)
All good but need more lights in room

Reviewed on Nov 30, 2025

Park Inn by Radisson Florence, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South Carolina Midlands

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great South Carolina Midlands hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South Carolina Midlands. No matter your reason for visiting South Carolina Midlands, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South Carolina Midlands hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in South Carolina Midlands?

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How to find cheap car rentals in South Carolina Midlands?

Finding a cheap car rental deal in South Carolina Midlands is as easy as scoring cheap hotels in South Carolina Midlands. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.