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Hotels in South Carolina Midlands

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Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 34 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,273 reviews)
"We enjoyed our stay, quite relaxing. Barbara, who just so happen to be doing the audit thewas extraordinary!"

Reviewed on Nov 2, 2026

Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Williams Brice Stadium and Colonial ...
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
  • 25 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Sleep Inn Columbia
Clarion Pointe Rock Hill Near University

Clarion Pointe Rock Hill Near University

2.5 out of 5
1106 N. Anderson Road Rock Hill SC
  • 3 hours drive from Fort Jackson
Stay at this hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,068 reviews)
"Tout était bien"

Reviewed on Nov 2, 2026

Clarion Pointe Rock Hill Near University
Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

2.5 out of 5
400 Gervais Street Columbia SC
  • 15 min drive from Fort Jackson
Stay at this hotel in Columbia. Enjoy free breakfast, a fitness center, and parking (surcharge). Popular attractions Colonial Life Arena and Riverbanks Zoo and ...
9.4/10 Exceptional! (973 reviews)
"Hotel was clean, room did not have anyplace to put your clothes, had a couple of hangers but no type of dresser. Had a shelf that Im assuming may have been to put things. Room was small with 2 queen beds, but everything was clean."

Reviewed on Nov 2, 2026

Tru By Hilton Columbia Downtown
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
  • 13 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,003 reviews)
"Miss Aimee at the front desk is wonderful!! She makes you feel welcome and addresses any needs you have."

Reviewed on Nov 1, 2026

Courtyard by Marriott Columbia Downtown at USC
Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone

2.5 out of 5
185 Stoneridge Drive Columbia SC
  • 19 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,156 reviews)
"This is the 2nd time I booked this hotel in 2 weeks because I loved it so much! Staff is so friendly! Rooms are super clean. Very reasonable price! Breakfast is a nice touch! The river walk is a 3 min drive and it’s awesome! Highly recommend!"

Reviewed on Nov 1, 2026

Tru By Hilton Columbia Greystone
Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia, SC

2.5 out of 5
220 E Exchange Blvd Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Country Inn & Suites by Radisson, Columbia, SC
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
  • 3 hours drive from Fort Jackson
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,497 reviews)
"Very nice and clean hotel. Good breakfast, comfortable beds. Close to 95, but very quiet"

Reviewed on Nov 2, 2026

Park Inn by Radisson Florence, SC
Motel 6 Columbia, SC - Fort Jackson Area

Motel 6 Columbia, SC - Fort Jackson Area

2 out of 5
7541 Nates Rd Columbia SC
  • 9 min drive from Fort Jackson
Stay at this motel in Columbia. Enjoy free WiFi, free parking, and a snack bar/deli. Popular attractions Richland County Tennis Center and Richland Library Northeast ...
4.8/10 (1,012 reviews)
"."

Reviewed on Nov 2, 2026

Motel 6 Columbia, SC - Fort Jackson Area
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

3 out of 5
1539 Horseshoe Dr Columbia SC
  • 9 min drive from Fort Jackson
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Wyndham Garden Columbia/Ft. Jackson
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
  • 3 hours drive from Fort Jackson
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,759 reviews)
"Desayuno limitado pero bueno."

Reviewed on Nov 2, 2026

Howard Johnson by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South Carolina Midlands

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in South Carolina Midlands.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of South Carolina Midlands’s 3,384 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $63. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great South Carolina Midlands hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South Carolina Midlands. No matter your reason for visiting South Carolina Midlands, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South Carolina Midlands hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in South Carolina Midlands for as low as $63.

How many hotels are there in South Carolina Midlands?

With over 3,384 hotels in South Carolina Midlands, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $63.

How to find cheap car rentals in South Carolina Midlands?

Finding a cheap car rental deal in South Carolina Midlands is as easy as scoring cheap hotels in South Carolina Midlands. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.