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Featured Luxury South Carolina Midlands
The Ballantyne, A Luxury Collection Hotel, Charlotte
10000 Ballantyne Commons Pkwy, Charlotte, NC
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Charlotte. Enjoy free WiFi, free parking, and 2 indoor pools. Our guests praise the helpful staff and the property condition ...
The Willcox
100 Colleton Avenue SW, Aiken, SC
Stay at this 3.5-star business-friendly hotel in Aiken. Enjoy free breakfast, free parking, and a fitness center. Popular attractions St. Mary Help of Christians ...
The Mantissa Hotel
130 East Carolina Ave, Hartsville, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Travelodge by Wyndham Orangeburg
3620 Saint Matthews Rd, Orangeburg, SC
Fully refundableReserve now, pay when you stay
Stay at this motel in Orangeburg. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Carriage House Inn
139 Laurens Street, Northwest , Aiken, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Aiken. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Microtel Inn & Suites by Wyndham Rock Hill/Charlotte Area
1047 Riverview Rd, Rock Hill, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Inn on the Square, Ascend Hotel Collection
104 Court Avenue East, Greenwood, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Greenwood. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Sheraton Columbia Downtown Hotel
1400 Main St, Columbia, SC
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and ...
Baymont by Wyndham Greenwood
109 Enterprise Ct, Greenwood, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Greenwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Red Roof Inn Santee
9091 Old Hwy 6, Santee, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Super 8 by Wyndham Columbia SC / Ft. Jackson
5321 Forest Dr, Columbia, SC
Fully refundableReserve now, pay when you stay
Stay at this motel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Williams ...
Days Inn by Wyndham Dillon
823 Radford Blvd, Dillon, SC
Fully refundableReserve now, pay when you stay
Stay at this hotel in Dillon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in South Carolina Midlands
- Hotels with Free Parking in South Carolina Midlands
- Family Hotels in South Carolina Midlands
- Hotels with a Pool in South Carolina Midlands
- Pet-friendly Hotels in South Carolina Midlands
- Historic Hotels in South Carolina Midlands
- Hotels with Hot Tubs in South Carolina Midlands
- Apartment Hotel in South Carolina Midlands
- Hotels with an Indoor Pool in South Carolina Midlands
- Resorts & Hotels with Spas in South Carolina Midlands
- Hotel Wedding Venues in South Carolina Midlands
South Carolina Midlands Neighborhoods
- Downtown Columbia Hotels (11.04 mi)
- Ballantyne Hotels (67.97 mi)
- Lake Wylie Hotels (72.42 mi)
- Lakemont Hotels (76.72 mi)
- Tega Cay Hotels (66.55 mi)
- University Hill Hotels (10.43 mi)
- Arsenal Hill Hotels (11.3 mi)
- Melrose Heights Hotels (9.05 mi)
- Old Shandon Hotels (9.62 mi)
- Lyon Street Hotels (9.51 mi)
- Earlewood Hotels (11.53 mi)
Top Points of Interests in South Carolina Midlands
- Hotels near Fort Jackson
- Hotels near Carowinds Theme Park
- Hotels near University of South Carolina
- Hotels near Riverbanks Zoo and Garden
- Hotels near Rock Hill Sports & Event Center
- Hotels near Darlington Raceway
- Hotels near Williams Brice Stadium
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Colonial Life Arena
- Hotels near Shaw Air Force Base
- Hotels near Columbia Metropolitan Convention Center
- Hotels near Congaree National Park
- Hotels near Village at Sandhill Mall
- Hotels near South Carolina State Fairgrounds
- Hotels near Lake Wylie
- Hotels near Township Auditorium
- Hotels near Mcleod Regional Medical Center
- Hotels near Rock Hill Galleria
- Hotels near Columbiana Centre
Cities near South Carolina Midlands
- Columbia Hotels (10.91 mi)
- Augusta Hotels (75.58 mi)
- Florence Hotels (63.1 mi)
- Concord Hotels (93.79 mi)
- Rock Hill Hotels (59.76 mi)
- Summerville Hotels (82.66 mi)
- Spartanburg Hotels (86 mi)
- Georgetown Hotels (101.94 mi)
- Anderson Hotels (106.34 mi)
- Aiken Hotels (60.64 mi)
- Fort Mill Hotels (64.88 mi)
- Conway Hotels (105.13 mi)
- Santee Hotels (45.91 mi)
- Coastal South Carolina Hotels (85.41 mi)
- Gastonia Hotels (84.31 mi)
- Huntersville Hotels (92.56 mi)
- Orangeburg Hotels (39.94 mi)
- Lexington Hotels (22.3 mi)
- Walterboro Hotels (81.4 mi)
- Matthews Hotels (72.64 mi)
Car Rentals Near South Carolina Midlands
- Car rentals in Columbia
- Car rentals in Augusta
- Car rentals in Florence
- Car rentals in Concord
- Car rentals in Rock Hill
- Car rentals in Summerville
- Car rentals in Spartanburg
- Car rentals in Georgetown
- Car rentals in Anderson
- Car rentals in Aiken
- Car rentals in Fort Mill
- Car rentals in Conway
- Car rentals in Santee
- Car rentals in Coastal South Carolina
- Car rentals in Gastonia
- Car rentals in Huntersville
Top Luxury Hotel Destinations
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- Springfield Luxury Hotels
- Flagstaff Luxury Hotels
- Tuscaloosa Luxury Hotels
- Toledo Luxury Hotels
- Traverse City Luxury Hotels
- Twin Falls Luxury Hotels
- Scranton Luxury Hotels
- Columbia Luxury Hotels
- Catalina Island Luxury Hotels
- Shreveport Luxury Hotels
- Tallahassee Luxury Hotels