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Spa Resort Hotels in South Carolina Midlands

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Featured South Carolina Midlands Resorts & Hotels with Spas

The Ballantyne, A Luxury Collection Hotel, Charlotte
The Ballantyne, A Luxury Collection Hotel, Charlotte
5 out of 5
10000 Ballantyne Commons Pkwy, Charlotte, NC
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Charlotte. Enjoy free WiFi, free parking, and 2 indoor pools. Our guests praise the helpful staff and the property condition ...
The Ballantyne, A Luxury Collection Hotel, Charlotte
Country Inn & Suites by Radisson, Columbia, SC
Country Inn & Suites by Radisson, Columbia, SC
2.5 out of 5
220 E Exchange Blvd, Columbia, SC
Fully refundable
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Country Inn & Suites by Radisson, Columbia, SC
Courtyard by Marriott Columbia Northeast/Fort Jackson Area
Courtyard by Marriott Columbia Northeast/Fort Jackson Area
3 out of 5
111 Gateway Corporate Blvd, Columbia, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star golf hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our ...
Courtyard by Marriott Columbia Northeast/Fort Jackson Area
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
2.5 out of 5
3440 W Radio Dr, Florence, SC
Fully refundable
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an IHG Hotel
Candlewood Suites Sumter, an IHG Hotel
Candlewood Suites Sumter, an IHG Hotel
2.5 out of 5
2541 Broad St, Sumter, SC
Fully refundable
Book a stay at this business-friendly hotel in Sumter. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Sumter Mall and Palmetto ...
Candlewood Suites Sumter, an IHG Hotel
Clarion Inn & Suites Aiken South
Clarion Inn & Suites Aiken South
2.5 out of 5
155 Colony Pkwy, Aiken, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Aiken. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Clarion Inn & Suites Aiken South
Comfort Inn & Suites Ft. Jackson Maingate
Comfort Inn & Suites Ft. Jackson Maingate
2.5 out of 5
7337 Garners Ferry Rd, Columbia, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Comfort Inn & Suites Ft. Jackson Maingate
Comfort Suites Rock Hill Manchester Meadows Area
Comfort Suites Rock Hill Manchester Meadows Area
2.5 out of 5
1323 Old Springdale Rd, Rock Hill, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Comfort Suites Rock Hill Manchester Meadows Area
Inn at Orangeburg
Inn at Orangeburg
2.5 out of 5
731 Citadel Road, Orangeburg, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Inn at Orangeburg
Country Inn & Suites by Radisson, Aiken, SC
Country Inn & Suites by Radisson, Aiken, SC
2.5 out of 5
3270 Whiskey Rd, Aiken, SC
Fully refundable
Book a stay at this business-friendly hotel in Aiken. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Country Inn & Suites by Radisson, Aiken, SC
Country Inn & Suites by Radisson, Rock Hill, SC
Country Inn & Suites by Radisson, Rock Hill, SC
2.5 out of 5
865 Patriot Pkwy, Rock Hill, SC
Book a stay at this business-friendly hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Country Inn & Suites by Radisson, Rock Hill, SC
Courtyard by Marriott Ballantyne
Courtyard by Marriott Ballantyne
3 out of 5
15635 Don Lochman Lane, Charlotte, NC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Charlotte. Enjoy free parking, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Courtyard by Marriott Ballantyne
See all 2,720 properties in South Carolina Midlands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.