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Featured South Carolina Midlands Family Hotels
Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Country Inn & Suites by Radisson, Aiken, SC
3270 Whiskey Rd, Aiken, SC
Book a stay at this business-friendly hotel in Aiken. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hyatt Place Columbia/Downtown/The Vista
819 Gervais Street, Columbia, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd, Columbia, SC
Fully refundable
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Beaver Creek Golf Club and Palmetto ...
Hampton Inn & Suites Columbia/Southeast-Ft. Jackson
201 East Exchange Boulevard, Columbia, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
SpringHill Suites by Marriott Columbia Downtown/The Vista
511 Lady Street, Columbia, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
Hyatt Place Columbia/Harbison
1130 Kinley Road, Irmo, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Irmo. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
Homewood Suites by Hilton Columbia
230 Greystone Blvd, Columbia, SC
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
Baymont by Wyndham Columbia Northwest
347 Zimalcrest Drive, Columbia, SC
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and BTM ...
Baymont by Wyndham Columbia Fort Jackson
240 E Exchange Blvd, Columbia, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Spark by Hilton Rock Hill
760 Galleria Blvd, Rock Hill, SC
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Rock Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in South Carolina Midlands
Country Inn & Suites by Radisson, Columbia, SC
220 E Exchange Blvd, Columbia, SC
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (1,022 reviews)
"Good place at a good price. Clean, good service and quite the decent breakfast;"
Reviewed on May 18, 2025
Baymont by Wyndham Columbia Northwest
347 Zimalcrest Drive, Columbia, SC
Book a stay at this family-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Riverbanks Zoo and Garden and BTM ...
5.4/10 (1,002 reviews)
"Friendly"
Reviewed on May 19, 2025
Best Western Plus Santee Inn
I 95 Exit 98, Santee, SC
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,001 reviews)
Nice stop.
"Great location. Traveling with dogs and they provide a great place for potty break and walks. Very clean and beds were comfortable. Bathroom was clean , could use a update . Breakfast was nice. Staff was friendly."
Reviewed on May 1, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in South Carolina Midlands
Aloft Columbia Downtown
823 Lady St, Columbia, SC
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Baymont by Wyndham Columbia Fort Jackson
240 E Exchange Blvd, Columbia, SC
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Beaver Creek Golf Club and Palmetto ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in South Carolina Midlands
- Hotels with a Pool in South Carolina Midlands
- Pet-friendly Hotels in South Carolina Midlands
- Historic Hotels in South Carolina Midlands
- Luxury Hotels in South Carolina Midlands
- Hotels with Hot Tubs in South Carolina Midlands
- Apartment Hotel in South Carolina Midlands
- Hotels with an Indoor Pool in South Carolina Midlands
- Resorts & Hotels with Spas in South Carolina Midlands
- Hotel Wedding Venues in South Carolina Midlands
South Carolina Midlands Neighborhoods
- Downtown Columbia Hotels (11.04 mi)
- Lake Wylie Hotels (72.42 mi)
- Ballantyne Hotels (67.97 mi)
- The Vista Hotels (11.29 mi)
- Tega Cay Hotels (66.55 mi)
- Lakemont Hotels (76.72 mi)
- University Hill Hotels (10.43 mi)
- Five Points Hotels (10.08 mi)
- Melrose Heights Hotels (9.05 mi)
- Old Town Rock Hill Hotels (59.91 mi)
Top Points of Interests in South Carolina Midlands
- Hotels near Carowinds Theme Park
- Hotels near Fort Jackson
- Hotels near University of South Carolina
- Hotels near Williams Brice Stadium
- Hotels near Riverbanks Zoo and Garden
- Hotels near Darlington Raceway
- Hotels near Colonial Life Arena
- Hotels near Florence Civic Center
- Hotels near Rock Hill Sports & Event Center
- Hotels near Congaree National Park
- Hotels near Shaw Air Force Base
- Hotels near Columbia Metropolitan Convention Center
- Hotels near Village at Sandhill Mall
- Hotels near Magnolia Mall
- Hotels near Rock Hill Galleria
- Hotels near South Carolina State Fairgrounds
- Hotels near Lake Wylie
- Hotels near Township Auditorium
- Hotels near Cherry Park
- Hotels near Francis Marion University
Cities near South Carolina Midlands
- Columbia Hotels (10.91 mi)
- Augusta Hotels (75.58 mi)
- Concord Hotels (93.79 mi)
- Florence Hotels (63.1 mi)
- Rock Hill Hotels (59.76 mi)
- Summerville Hotels (82.66 mi)
- Spartanburg Hotels (86 mi)
- Anderson Hotels (106.34 mi)
- Fort Mill Hotels (64.88 mi)
- Georgetown Hotels (101.94 mi)
- Conway Hotels (105.13 mi)
- Huntersville Hotels (92.56 mi)
- Santee Hotels (45.91 mi)
- Aiken Hotels (60.64 mi)
- Gastonia Hotels (84.31 mi)
- Walterboro Hotels (81.4 mi)
- Matthews Hotels (72.64 mi)
- Orangeburg Hotels (39.94 mi)
- Lumberton Hotels (112.25 mi)
- Lexington Hotels (22.3 mi)
Car Rentals Near South Carolina Midlands
- Car rentals in Columbia
- Car rentals in Augusta
- Car rentals in Concord
- Car rentals in Florence
- Car rentals in Rock Hill
- Car rentals in Summerville
- Car rentals in Spartanburg
- Car rentals in Anderson
- Car rentals in Fort Mill
- Car rentals in Georgetown
- Car rentals in Conway
- Car rentals in Huntersville
- Car rentals in Santee
- Car rentals in Aiken
- Car rentals in Gastonia
- Car rentals in Walterboro
Top Family Hotel Destinations
- Las Vegas Family Hotels
- Arcade Family Hotels
- Branson Family Hotels
- Biloxi Family Hotels
- Ocean City Family Hotels
- Orlando Family Hotels
- Buffalo Family Hotels
- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in South Carolina Midlands
- Hilton Garden Inn Columbia/Harbison
- Courtyard by Marriott Columbia Downtown at USC
- Clarion Pointe Near University
- Howard Johnson by Wyndham Florence
- Sleep Inn Columbia
- Graduate by Hilton Columbia SC
- Quality Inn & Suites Florence Civic Center
- Hyatt Place Columbia/Downtown/The Vista
- Hampton Inn & Suites Columbia Killian Road
- Country Inn & Suites by Radisson, Columbia, SC