Adults Only Resorts & Hotels in
South Carolina Midlands

Check Last Minute South Carolina Midlands Hotel Deals

Tonight Nov 15 - Nov 16This weekend Nov 15 - Nov 17

Featured South Carolina Midlands Adults Only Resorts & Hotels

Baymont by Wyndham Orangeburg North
Baymont by Wyndham Orangeburg North
2.5 out of 5
3583 Saint Matthews Rd, Orangeburg, SC
The price is $73 per night from Dec 1 to Dec 2
$73
includes taxes & fees
Dec 1 - Dec 2
Baymont by Wyndham Orangeburg North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in South Carolina Midlands

South Carolina is a city that has a lot going on, but you have your sights set on South Carolina Midlands. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that South Carolina Midlands has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of South Carolina Midlands hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of South Carolina so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the South Carolina Midlands underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the South Carolina Midlands city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of South Carolina Midlands cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in South Carolina Midlands at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $73
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the South Carolina Midlands hotel you want, book it, and never look back. Because your great escape is ahead of you.