Search Deals onClayton Vacation Packages
Clayton Flight + Hotel packages
![Sonesta ES Suites St. Louis - Chesterfield](https://images.trvl-media.com/lodging/1000000/10000/500/422/c3442609_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Sonesta ES Suites St. Louis - Chesterfield
![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/4059f405_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
The Wildwood Hotel
![The Charles F. Knight Center](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/4865eb6e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
The Charles F. Knight Center
![The Cheshire](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/2811db1a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
The Cheshire
![Crowne Plaza St. Louis Airport, an IHG Hotel](https://images.trvl-media.com/lodging/1000000/10000/3100/3010/db9ce393_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Crowne Plaza St. Louis Airport, an IHG Hotel
![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/6f5c3bb0_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Ameristar Casino Resort and Spa
![Hilton Pennywell St. Louis at the Arch](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/0efe8f50_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Hilton Pennywell St. Louis at the Arch
![Hilton Garden Inn Chesterfield](https://images.trvl-media.com/lodging/1000000/300000/297100/297075/2a45ee7c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Hilton Garden Inn Chesterfield
3-4 Night Vacations in Clayton
![Crowne Plaza St. Louis Airport, an IHG Hotel](https://images.trvl-media.com/lodging/1000000/10000/3100/3010/db9ce393_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/4059f405_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
![The Charles F. Knight Center](https://images.trvl-media.com/lodging/39000000/38720000/38711900/38711810/4865eb6e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Cheap Hotel Deals in Clayton
![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Clayton Plaza Hotel & Extended Stay
![Le Méridien St. Louis Clayton](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/6c844457_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Le Méridien St. Louis Clayton
![Hampton Inn & Suites Clayton/St. Louis-Galleria Area](https://images.trvl-media.com/lodging/1000000/20000/17600/17599/86b85a9d_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
![Homewood Suites by Hilton St Louis - Galleria](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665070/c0e33c2f_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Homewood Suites by Hilton St Louis - Galleria
![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/54a421cf_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hyatt Regency St. Louis at The Arch
![Hollywood Casino & Hotel St. Louis](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Hollywood Casino & Hotel St. Louis
![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/56fc52a7_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Drury Plaza Hotel St. Louis at the Arch
![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/5dc334bf_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Pear Tree Inn St. Louis Airport
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
![Frontier Airlines](http://images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/F9.gif)
![Frontier Airlines](http://images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/F9.gif)
![Frontier Airlines](http://images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/F9.gif)
![Frontier Airlines](http://images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/F9.gif)
Find cheap hotels in Clayton
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Clayton hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in Clayton.
Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Clayton’s 1,901 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $95. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Clayton hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Clayton. No matter your reason for visiting Clayton, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Clayton hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Clayton for as low as $95.
How many hotels are there in Clayton?
With over 1,901 hotels in Clayton, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $95.
How to find cheap car rentals in Clayton?
Finding a cheap car rental deal in St. Louis is as easy as scoring cheap hotels in Clayton. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.
Is it safe to travel to Clayton now?
With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Clayton right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.
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