Search Deals onHistoric Main Street Vacation Packages
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Historic Main Street Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Wingate by Wyndham St. Louis/Fenton Route 66
per person
Mar 14 - Mar 19
found 19 hours ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Simpson Park and LIFECHURCH are located nearby.
The Wildwood Hotel
per person
Mar 14 - Mar 19
found 2 days ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Stay at this 3.5-star business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Skid Row and Hidden Valley Ski Resort are located nearby.
The Cheshire
per person
Mar 14 - Mar 19
found 1 day ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Stay at this 4-star boutique hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions St. Louis Union Station and St. Louis Zoo are located nearby.
Moonrise Hotel
per person
Mar 14 - Mar 19
found 2 days ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. Popular attractions St. Louis Zoo and St. Louis Union Station are located nearby.
Missouri Athletic Club
per person
Mar 17 - Mar 21
found 23 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to St. Louis (STL)
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the comfy rooms in our reviews. Popular attractions St. Louis Union Station and Dome at America’s Center are located nearby.
Crowne Plaza St. Louis Airport, an IHG Hotel
per person
Mar 14 - Mar 19
found 2 days ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Stay at this 3.5-star business-friendly hotel in Bridgeton. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular attractions Hollywood Casino Amphitheatre and Westport Plaza are located nearby.
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
per person
Mar 14 - Mar 19
found 1 day ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Simpson Park and LIFECHURCH are located nearby.
Hilton Garden Inn Chesterfield
per person
Mar 14 - Mar 19
found 1 day ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Stay at this 3-star business-friendly hotel in Chesterfield. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Topgolf and Taubman Prestige Outlets are located nearby.
Homewood Suites by Hilton St. Louis Riverport - Airport West
per person
Mar 14 - Mar 19
found 1 day ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Stay at this 3-star business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Hollywood Casino Amphitheatre and Ameristar Casino St. Charles are located nearby.
DoubleTree by Hilton Hotel St. Louis - Chesterfield
per person
Mar 14 - Mar 19
found 1 day ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Book a stay at this business-friendly hotel in Chesterfield. Enjoy free parking, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Chesterfield Arts and Westfield Chesterfield Mall are located nearby.
Wingate by Wyndham St. Louis Airport
per person
Mar 14 - Mar 19
found 2 days ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Bigfoot 4 x 4 Inc and Blanche M. Touhill Performing Arts Center are located nearby.
275 On The Park - Senate Apartments By Barsala
per person
Mar 17 - Mar 21
found 10 hours ago
Roundtrip non-stop flight included
Tampa (TPA) to St. Louis (STL)
Stay at this 4-star aparthotel in St. Louis. Enjoy free WiFi, a fitness center, and in-room washers/dryers. Popular attractions St. Louis Zoo and St. Louis Union Station are located nearby.
3-4 Night Vacations in Historic Main Street
Price found within the past 48 hours. Click for updated prices.
5-7 Night Vacations in Historic Main Street
Price found within the past 48 hours. Click for updated prices.
Historic Main Street Last Minute Hotel Deals
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St, St. Charles, MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Best Western Plus The Charles Hotel
1425 South 5th Street, St. Charles, MO
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hampton Inn & Suites St. Charles Old Town Area
1410 SOUTH 5TH STREET, St. Charles, MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Embassy Suites by Hilton St. Louis St. Charles
2 Convention Center Plz, St. Charles, MO
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and ...
Baymont by Wyndham St. Charles
801 Veterans Memorial Parkway, St. Charles, MO
Stay at this hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels Near Points of Interest in Historic Main Street
- Hotels near First Missouri State Capitol Historic Site
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- Hotels near Hollywood Casino Amphitheatre
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
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Car Rentals in Historic Main Street
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- Car rentals in Kirkwood
- Car rentals in Southern Illinois
- Car rentals in Bridgeton