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Otay Mesa Vacation Packages

Otay Mesa Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Stay Classy Hostel

Stay Classy Hostel

2 out of 5
Downtown San Diego
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Stay at this hostel in San Diego. Enjoy free WiFi, a 24-hour front desk, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions Port of San Diego and San Diego Zoo are located nearby.
Mission View Inn & Suites San Diego Sea World - Zoo

Mission View Inn & Suites San Diego Sea World - Zoo

2.5 out of 5
Mission Valley
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the clean rooms and the overall value in our reviews. Popular attractions San Diego Zoo and Port of San Diego are located nearby.
Chula Vista Inn

Chula Vista Inn

2.5 out of 5
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Stay at this hotel in Chula Vista. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Las Americas Premium Outlets and Chula Vista Center are located nearby.
Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego

2 out of 5
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Stay at this motel in El Cajon. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Parkway Plaza and Olaf Wieghorst Museum and Western Heritage Center are located nearby.
Days Inn by Wyndham Encinitas Moonlight Beach

Days Inn by Wyndham Encinitas Moonlight Beach

2 out of 5
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Stay at this motel in Encinitas. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions LEGOLAND® California and Moonlight State Beach are located nearby.
Rodeway Inn Encinitas North

Rodeway Inn Encinitas North

2 out of 5
Leucadia
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Stay at this hotel in Encinitas. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions LEGOLAND® California and Leucadia State Beach are located nearby.
Heritage Inn San Diego

Heritage Inn San Diego

2 out of 5
Point Loma
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the clean rooms in our reviews. Popular attractions Mission Bay and Port of San Diego are located nearby.
Hotel Iris - San Diego

Hotel Iris - San Diego

2.5 out of 5
Mission Valley
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy a 24-hour front desk, laundry facilities, and premium TV channels. Our guests praise the helpful staff in our reviews. Popular attractions San Diego Zoo and Port of San Diego are located nearby.

3-4 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express Mira Mesa-San Diego, an IHG Hotel

Holiday Inn Express Mira Mesa-San Diego, an IHG Hotel

2.5 out of 5
Scripps Ranch
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

3 out of 5
Point Loma
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4 out of 5
Downtown San Diego
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Sonesta ES Suites Carmel Mountain – San Diego

Sonesta ES Suites Carmel Mountain – San Diego

3 out of 5
Carmel Mountain Ranch
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)

5-7 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Stay Classy Hostel

Stay Classy Hostel

2 out of 5
Downtown San Diego
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Mission View Inn & Suites San Diego Sea World - Zoo

Mission View Inn & Suites San Diego Sea World - Zoo

2.5 out of 5
Mission Valley
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Chula Vista Inn

Chula Vista Inn

2.5 out of 5
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)
Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego

2 out of 5
per person
Mar 10 - Mar 15
found 24 hours ago
Roundtrip flight included
Minneapolis (MSP) to San Diego (SAN)

Cheap Hotel Deals in Otay Mesa

Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 spa tubs. Our guests praise the pool and the restaurant in our ...
Best Western Seven Seas
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 spa tubs. Our guests praise the pool and the restaurant in ...
The Dana on Mission Bay
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
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Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd, San Diego, CA
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd, San Diego, CA
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Hyatt Regency Mission Bay Spa and Marina
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd, San Diego, CA
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
Wyndham Garden San Diego Near SeaWorld
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and room service. Our guests praise the breakfast and the restaurant in ...
Bay Club Hotel & Marina
Comfort Inn Sea World Area

Comfort Inn Sea World Area

3.5 out of 5
3880 Greenwood St, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Comfort Inn Sea World Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Feb 18 - Thu, Feb 20
SFO
San Francisco Intl.
SAN
San Diego Intl.
$48 Roundtrip, found 2 days ago
$48
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Tue, Feb 18 from San Francisco Intl. to San Diego Intl., returning Thu, Feb 20, priced at $48 found 2 days ago
Frontier Airlines
Tue, Feb 25 - Wed, Feb 26
DFW
Dallas-Fort Worth Intl.
SAN
San Diego Intl.
$68 Roundtrip, found 5 days ago
$68
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Tue, Feb 25 from Dallas-Fort Worth Intl. to San Diego Intl., returning Wed, Feb 26, priced at $68 found 5 days ago
Frontier Airlines
Tue, Feb 11 - Tue, Feb 18
DEN
Denver Intl.
SAN
San Diego Intl.
$68 Roundtrip, found 5 days ago
$68
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Tue, Feb 11 from Denver Intl. to San Diego Intl., returning Tue, Feb 18, priced at $68 found 5 days ago
Frontier Airlines
Sat, Feb 8 - Wed, Feb 12
PDX
Portland Intl.
SAN
San Diego Intl.
$88 Roundtrip, found 1 day ago
$88
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Feb 8 from Portland Intl. to San Diego Intl., returning Wed, Feb 12, priced at $88 found 1 day ago