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Otay Mesa Vacation Packages

Otay Mesa Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
Save 100% on your flight
per person
May 19 - May 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4 out of 5
Downtown San Diego
Save 100% on your flight
per person
May 29 - Jun 4
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4-star boutique hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
Mission Beach
Save 100% on your flight
per person
May 19 - May 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
Kona Kai San Diego

Kona Kai San Diego

4 out of 5
Point Loma
Save 100% on your flight
per person
May 19 - May 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4-star beach hotel in San Diego. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Coronado Beach and USS Midway Museum are located nearby.
Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
Central Mission Beach
Save 100% on your flight
per person
May 29 - Jun 4
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Book a stay at this beach resort in San Diego. Enjoy free parking, a beach locale, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
City24 Hotel Little Italy Mission Hill

City24 Hotel Little Italy Mission Hill

4.5 out of 5
Middletown
Save 100% on your flight
per person
May 15 - May 19
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4.5-star luxury aparthotel in San Diego. Enjoy free WiFi, a rooftop terrace, and parking (surcharge). Popular attractions Port of San Diego and San Diego Zoo are located nearby.
Surfer Beach Hotel

Surfer Beach Hotel

3 out of 5
Pacific Beach
Save 100% on your flight
per person
May 15 - May 19
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 3-star beach hotel in San Diego. Enjoy free WiFi, a beach locale, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
Ocean View Luxury Condo

Ocean View Luxury Condo

4 out of 5
Pacific Beach
Save 100% on your flight
per person
May 19 - May 23
found 1 day ago
Roundtrip non-stop flight included
Salt Lake City (SLC) to San Diego (SAN)
Stay at this 4-star condo in San Diego. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Mission Beach and Mission Bay are located nearby.

3-4 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Pala Casino Spa And Resort

Pala Casino Spa And Resort

4 out of 5
Save 100% on your flight
per person
May 9 - May 12
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Roam and Board

Roam and Board

2 out of 5
Save 100% on your flight
per person
May 15 - May 18
found 22 hours ago
Roundtrip non-stop flight included
Salt Lake City (SLC) to San Diego (SAN)
The Dextro Hotel, BW Premier Collection

The Dextro Hotel, BW Premier Collection

3 out of 5
Downtown San Diego
per person
May 7 - May 10
found 1 day ago
Roundtrip flight included
Dallas (DAL) to San Diego (SAN)
Ocean View Luxury Condo

Ocean View Luxury Condo

4 out of 5
Pacific Beach
Save 100% on your flight
per person
May 19 - May 23
found 1 day ago
Roundtrip non-stop flight included
Salt Lake City (SLC) to San Diego (SAN)

5-7 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4 out of 5
Downtown San Diego
Save 100% on your flight
per person
May 29 - Jun 4
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
Mission Beach
Save 100% on your flight
per person
May 19 - May 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Kona Kai San Diego

Kona Kai San Diego

4 out of 5
Point Loma
Save 100% on your flight
per person
May 19 - May 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Save 100% on your flight
per person
May 29 - Jun 4
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)

Cheap Hotel Deals in Otay Mesa

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
The Dana on Mission Bay
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Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Manchester Grand Hyatt San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd, San Diego, CA
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
Hilton San Diego Mission Valley
Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr, San Diego, CA
Book a stay at this beach resort in San Diego. Enjoy free parking, a beach locale, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
Bahia Resort Hotel
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr, San Diego, CA
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
San Diego Mission Bay Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Apr 8 - Thu, Apr 10
SFO
San Francisco Intl.
SAN
San Diego Intl.
$70 Roundtrip, found 3 days ago
$70
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Apr 8 from San Francisco Intl. to San Diego Intl., returning Thu, Apr 10, priced at $70 found 3 days ago
Spirit Airlines
Tue, Apr 29 - Wed, Apr 30
SEA
Seattle - Tacoma Intl.
SAN
San Diego Intl.
$72 Roundtrip, found 22 hours ago
$72
Roundtrip
found 22 hours ago
Select Spirit Airlines flight, departing Tue, Apr 29 from Seattle - Tacoma Intl. to San Diego Intl., returning Wed, Apr 30, priced at $72 found 22 hours ago
Spirit Airlines
Mon, May 12 - Tue, May 13
PDX
Portland Intl.
SAN
San Diego Intl.
$92 Roundtrip, found 5 days ago
$92
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Mon, May 12 from Portland Intl. to San Diego Intl., returning Tue, May 13, priced at $92 found 5 days ago
Frontier Airlines
Wed, Jun 18 - Tue, Jun 24
DEN
Denver Intl.
SAN
San Diego Intl.
$108 Roundtrip, found 2 days ago
$108
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Wed, Jun 18 from Denver Intl. to San Diego Intl., returning Tue, Jun 24, priced at $108 found 2 days ago