Search Deals onOtay Mesa Vacation Packages
Otay Mesa Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
Quiet Mind Mountain Lodge, Retreat and Spa
per person
Jul 16 - Jul 20
found 16 hours ago
Roundtrip flight included
Houston (HOU) to San Diego (SAN)
Stay at this 4.5-star luxury lodge in Julian. Enjoy free parking, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Santa Ysabel Mission and Lake Cuyamaca are located nearby.
Little Italy Inn - Limited Service Apart Hotel
Downtown San Diego
Save 100% on your flight
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip non-stop flight included
Grand Junction (GJT) to San Diego (SAN)
Stay at this aparthotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
Motel San Diego - In San Diego (Pacific Beach)
Pacific Beach
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip non-stop flight included
Grand Junction (GJT) to San Diego (SAN)
Stay at this motel in San Diego. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.
Pala Casino Spa And Resort
Save 100% on your flight
per person
Jul 26 - Aug 3
found 8 hours ago
Roundtrip non-stop flight included
Cincinnati (CVG) to San Diego (SAN)
Stay at this 4-star hotel in Pala. Enjoy an outdoor pool, a casino, and a 24-hour front desk. Our guests praise the bar and the helpful staff in our reviews. Popular attractions Pala Casino Spa Resort and Pala Casino Spa & Resort are located nearby.
Hyatt Vacation Club at The Welk, San Diego Area
Lawrence Welk Resort Village
Save 100% on your flight
per person
Jul 26 - Aug 3
found 8 hours ago
Roundtrip non-stop flight included
Cincinnati (CVG) to San Diego (SAN)
Book a stay at this spa hotel in Escondido. Enjoy free parking, 8 outdoor pools, and a full-service spa. Our guests praise the pool and the clean rooms in our reviews. Popular attractions The Oaks Course and Cal-a-vie are located nearby.
Estancia La Jolla Hotel & Spa
La Jolla Farms
Save 100% on your flight
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip non-stop flight included
Grand Junction (GJT) to San Diego (SAN)
Stay at this 4-star spa hotel in La Jolla. Enjoy a full-service spa, 4 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Birch Aquarium and Torrey Pines Golf Course are located nearby.
Sand Castle Inn
Save 100% on your flight
per person
Jul 11 - Jul 17
found 12 hours ago
Roundtrip non-stop flight included
Houston (IAH) to San Diego (SAN)
Book a stay at this beach motel in Imperial Beach. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions San Diego Bay and Las Americas Premium Outlets are located nearby.
The Lodge at Torrey Pines
Torrey Pines
Save 100% on your flight
per person
Jul 16 - Jul 21
found 1 day ago
Roundtrip non-stop flight included
Grand Junction (GJT) to San Diego (SAN)
Stay at this 5-star luxury hotel in La Jolla. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Torrey Pines Golf Course and Birch Aquarium are located nearby.
3-4 Night Vacations in Otay Mesa
Price found within the past 48 hours. Click for updated prices.
5-7 Night Vacations in Otay Mesa
Price found within the past 48 hours. Click for updated prices.
Cheap Hotel Deals in Otay Mesa
Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Kings Inn San Diego
1333 Hotel Cir S, San Diego, CA
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
Save an average of 15% on thousands of hotels when you're signed in
The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
Loews Coronado Bay Resort
4000 Coronado Bay Rd, Coronado, CA
Stay at this 4-star beach hotel in Coronado. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Embassy Suites by Hilton San Diego Bay Downtown
601 Pacific Hwy, San Diego, CA
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Lafayette Hotel & Club
2223 El Cajon Blvd, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Tue, Jul 22 - Wed, Jul 30
SFO
San Francisco Intl.
SAN
San Diego Intl.
$57 Roundtrip, found 4 hours ago
$57
Roundtrip
found 4 hours ago
Tue, Jun 24 - Tue, Jul 1
DFW
Dallas-Fort Worth Intl.
SAN
San Diego Intl.
$105 Roundtrip, just found
$105
Roundtrip
just found
Tue, Nov 4 - Tue, Nov 4
SEA
Seattle - Tacoma Intl.
SAN
San Diego Intl.
$129 Roundtrip, found 3 days ago
$129
Roundtrip
found 3 days ago
Thu, Oct 2 - Sun, Oct 5
DEN
Denver Intl.
SAN
San Diego Intl.
$133 Roundtrip, found 8 hours ago
$133
Roundtrip
found 8 hours ago
Discover Other Travel Deals
- Cross Border Xpress Vacations
- San Diego Zoo Vacations
- Mission Bay Vacations
- San Diego Convention Center Vacations
- San Ysidro Border Crossing Vacations
- Mission Beach Vacations
- Petco Park Vacations
- Balboa Park Vacations
- Hotel Circle Vacations
- San Diego State University Vacations
- Naval Base San Diego Vacations