Search Deals onOtay Mesa Vacation Packages
Otay Mesa Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

The Dana on Mission Bay
Save 100% on your flight
per person
May 19 - May 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.

Alma San Diego Downtown, a Tribute Portfolio Hotel
Downtown San Diego
Save 100% on your flight
per person
May 29 - Jun 4
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4-star boutique hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.

Catamaran Resort and Spa
Mission Beach
Save 100% on your flight
per person
May 19 - May 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.

Kona Kai San Diego
Point Loma
Save 100% on your flight
per person
May 19 - May 24
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4-star beach hotel in San Diego. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Coronado Beach and USS Midway Museum are located nearby.

Bahia Resort Hotel
Central Mission Beach
Save 100% on your flight
per person
May 29 - Jun 4
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Diego (SAN)
Book a stay at this beach resort in San Diego. Enjoy free parking, a beach locale, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.

City24 Hotel Little Italy Mission Hill
Middletown
Save 100% on your flight
per person
May 15 - May 19
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 4.5-star luxury aparthotel in San Diego. Enjoy free WiFi, a rooftop terrace, and parking (surcharge). Popular attractions Port of San Diego and San Diego Zoo are located nearby.

Surfer Beach Hotel
Pacific Beach
Save 100% on your flight
per person
May 15 - May 19
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Diego (SAN)
Stay at this 3-star beach hotel in San Diego. Enjoy free WiFi, a beach locale, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.

Ocean View Luxury Condo
Pacific Beach
Save 100% on your flight
per person
May 19 - May 23
found 1 day ago
Roundtrip non-stop flight included
Salt Lake City (SLC) to San Diego (SAN)
Stay at this 4-star condo in San Diego. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Mission Beach and Mission Bay are located nearby.
3-4 Night Vacations in Otay Mesa
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in Otay Mesa
Price found within the past 48 hours. Click for updated prices.



Cheap Hotel Deals in Otay Mesa

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
Save an average of 15% on thousands of hotels when you're signed in

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...

Paradise Point Resort & Spa
1404 Vacation Rd, San Diego, CA
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

Hilton San Diego Mission Valley
901 Camino Del Rio S, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...

Bahia Resort Hotel
998 W Mission Bay Dr, San Diego, CA
Book a stay at this beach resort in San Diego. Enjoy free parking, a beach locale, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...

San Diego Mission Bay Resort
1775 E Mission Bay Dr, San Diego, CA
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Tue, Apr 8 - Thu, Apr 10
SFO
San Francisco Intl.
SAN
San Diego Intl.
$70 Roundtrip, found 3 days ago
$70
Roundtrip
found 3 days ago

Tue, Apr 29 - Wed, Apr 30
SEA
Seattle - Tacoma Intl.
SAN
San Diego Intl.
$72 Roundtrip, found 22 hours ago
$72
Roundtrip
found 22 hours ago

Mon, May 12 - Tue, May 13
PDX
Portland Intl.
SAN
San Diego Intl.
$92 Roundtrip, found 5 days ago
$92
Roundtrip
found 5 days ago

Wed, Jun 18 - Tue, Jun 24
DEN
Denver Intl.
SAN
San Diego Intl.
$108 Roundtrip, found 2 days ago
$108
Roundtrip
found 2 days ago
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