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Hotels in National City

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Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 out of 5
800 Bay Marina Dr National City CA
  • 4 min drive from Paradise Valley Medical Center
Book a stay at this golf hotel in National City. Enjoy free WiFi, free parking, and a golf course. Our guests praise the pool and the restaurant in our reviews. ...
9.2/10 Wonderful! (3,751 reviews)
Great location for base

Reviewed on Mar 3, 2026

Best Western Plus Marina Gateway Hotel
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
  • 17 min drive from Paradise Valley Medical Center
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,438 reviews)
Food was overpriced and not very good across the board. Gouged for parking. Not worth the cost.

Reviewed on Mar 3, 2026

Paradise Point Resort & Spa
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
  • 9 min drive from Paradise Valley Medical Center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9.2/10 Wonderful! (3,444 reviews)
My 3rd stay at Bay Club. Room, property and location is a real treat. Joshua at the front desk was very helpful.

Reviewed on Mar 2, 2026

Bay Club Hotel & Marina
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
  • 6 min drive from Paradise Valley Medical Center
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,368 reviews)
Didn't use pool

Reviewed on Mar 3, 2026

Hard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
  • 8 min drive from Paradise Valley Medical Center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,149 reviews)
The staff were friendly.

Reviewed on Mar 3, 2026

The DEXTRO Little Italy, BW Premier Collection
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
  • 14 min drive from Paradise Valley Medical Center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (2,523 reviews)
Even though our room was clean, our bed still had black ants crawling atop of it. Disappointing.

Reviewed on Mar 3, 2026

Days Inn by Wyndham San Diego Hotel Circle
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
  • 14 min drive from Paradise Valley Medical Center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
7.8/10 Good! (3,255 reviews)
The towels, pillow cases and beddings are too old and dirty

Reviewed on Mar 2, 2026

Best Western Seven Seas
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
  • 17 min drive from Paradise Valley Medical Center
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,352 reviews)
Great family resort with good location. You're 10 minutes away from everything (old Town, little Italy, etc.). Parking outside the resort is always packed. The onsite parking is a bit high but you don't really have an option.

Reviewed on Mar 3, 2026

San Diego Mission Bay Resort
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
  • 7 min drive from Paradise Valley Medical Center
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,794 reviews)
The hotel is in the downtown center. It was very convenient to restaurants, shops and sites of interest for tourists. The room was clean. The bed, TV, and furniture were nice. The staff was friendly and helpful.

Reviewed on Mar 2, 2026

The Sofia Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
  • 8 min drive from Paradise Valley Medical Center
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,067 reviews)
It was for pleasure. The room was clean the bed was good. The price point and location were excellent. I could not see the bay from my room and did not use the pool.

Reviewed on Mar 3, 2026

Wyndham San Diego Bayside
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

3 out of 5
3888 Greenwood St San Diego CA
  • 13 min drive from Paradise Valley Medical Center
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Mission ...
9.2/10 Wonderful! (693 reviews)
Check in and out was quick and easy, room and property were very clean, the bed was so comfortable, nice shower with adjustable pressure, and great breakfast buffet!

Reviewed on Mar 3, 2026

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy San Diego CA
  • 7 min drive from Paradise Valley Medical Center
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,660 reviews)
Great for a family stay, nice breakfast, clean, airy, enjoyed the social buzzing happy hour. Pool was a nice touch- open from 5am so perfect for the transatlantic arrivals. Location is brilliant- very close to all the amenities- Top Gun Bar practically next door! Highly recommend.

Reviewed on Mar 3, 2026

Embassy Suites by Hilton San Diego Bay Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in National City

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $84. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great National City hotel deals at the last minute.

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Frequently Asked Questions About National City hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in National City?

With over 7,802 hotels in National City, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $84.

How to find cheap car rentals in National City?

Finding a cheap car rental deal in National City is as easy as scoring cheap hotels in National City. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.