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Hotels in Santee

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Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
  • 25 min drive from Santee Lakes
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,803 reviews)
"Fantastic place, staff was excellent and location next to sea port village was amazing"

Reviewed on Jun 9, 2026

Manchester Grand Hyatt San Diego
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
  • 24 min drive from Santee Lakes
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,212 reviews)
"While staying here, I was impressed with nearly everything The Sofia had to offer from the gorgeous rooms, the hotels view, helpful staff, and even complementary goodies in the lobby. I will say I was not a fan of having learning that you must pay to park here as it’s not included in your reservation. ..."

Reviewed on Jun 10, 2026

The Sofia Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
  • 17 min drive from Santee Lakes
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
8/10 Very Good! (3,614 reviews)
"Great hotel for decent price. Housekeeping kept the room nice everyday."

Reviewed on Jun 10, 2026

Best Western Seven Seas
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
  • 23 min drive from Santee Lakes
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,176 reviews)
"the front desk made up too many excuses when the work needed to be done"

Reviewed on Jun 10, 2026

Wyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
  • 25 min drive from Santee Lakes
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,819 reviews)
"Great hotel and location is perfect for Radys Shell, Gaslamp or Petco Park"

Reviewed on Jun 10, 2026

Hard Rock Hotel San Diego
San Diego Mission Bay Resort

San Diego Mission Bay Resort

4 out of 5
1775 E Mission Bay Dr San Diego CA
  • 14 min drive from Santee Lakes
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (1,477 reviews)
"Very family friendly resort ! We enjoyed the pool and the restaurant with our daughter’s family and our young granddaughters. The hotel was able to provide connecting rooms which was wonderful and kept us connected the entire time, they also accommodated an early check in for a small fee and a late ..."

Reviewed on Jun 10, 2026

San Diego Mission Bay Resort
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
  • 6 min drive from Santee Lakes
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
7.8/10 Good! (2,635 reviews)
"Room was clean hot tube and pool were clean"

Reviewed on Jun 10, 2026

California Suites Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
  • 17 min drive from Santee Lakes
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
8/10 Very Good! (2,794 reviews)
"the place was just okay — the Air Conditioner is very old & has that “old smell” to it. Could’ve been cleaner. There was an incident where the San Diego Police Department was called. About 15 cop cars were there & we were not notified regarding this. If you have kids please be aware. Also — $20 a ..."

Reviewed on Jun 10, 2026

Days Inn by Wyndham San Diego Hotel Circle
Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4 out of 5
1500 Orange Ave Coronado CA
  • 30 min drive from Santee Lakes
Book a stay at this beach resort in Coronado. Enjoy free WiFi, 6 restaurants, and a private beach. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,020 reviews)
"Liked everything!!"

Reviewed on Jun 10, 2026

Hotel del Coronado, Curio Collection by Hilton
Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
  • 16 min drive from Santee Lakes
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,138 reviews)
"Location was nice"

Reviewed on Jun 10, 2026

Bahia Resort Hotel
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
  • 15 min drive from Santee Lakes
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,656 reviews)
"We had a room that faced the lagoon and we had the most wonderful experience with all the birds. Dining was terrific, the location is lovely and yet close to downtown and the beaches."

Reviewed on Jun 10, 2026

Paradise Point Resort & Spa
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
  • 24 min drive from Santee Lakes
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9.2/10 Wonderful! (3,652 reviews)
"👏"

Reviewed on Jun 10, 2026

Bay Club Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Santee

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santee.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Santee’s 9,844 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $113. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santee hotel deals at the last minute.

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Frequently Asked Questions About Santee hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Santee?

With over 9,844 hotels in Santee, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $113.

How to find cheap car rentals in Santee?

Finding a cheap car rental deal in Santee is as easy as scoring cheap hotels in Santee. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.