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Otay Mesa Vacation Packages

Otay Mesa Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Motel San Diego - In San Diego (Pacific Beach)

Motel San Diego - In San Diego (Pacific Beach)

2 out of 5
Pacific Beach
per person
Aug 7 - Aug 11
found 19 hours ago
Roundtrip flight included
Orlando (MCO) to San Diego (SAN)
Stay at this motel in San Diego. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
per person
Jul 31 - Aug 4
found 1 day ago
Roundtrip flight included
Orlando (MCO) to San Diego (SAN)
Stay at this 3.5-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and Seaport Village are located nearby.
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4 out of 5
Downtown San Diego
per person
Jul 31 - Aug 4
found 1 day ago
Roundtrip flight included
Orlando (MCO) to San Diego (SAN)
Stay at this 4-star boutique hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
Roam and Board

Roam and Board

2 out of 5
Save 100% on your flight
per person
Aug 2 - Aug 7
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to San Diego (SAN)
Book a stay at this golf campground in San Diego. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Mission Bay and Mission Beach are located nearby.
La Jolla Cove Suites

La Jolla Cove Suites

3 out of 5
Village of La Jolla
Save 100% on your flight
per person
Jul 24 - Jul 28
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to San Diego (SAN)
Book a stay at this beach hotel in La Jolla. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
Hampton Inn by Hilton Cardiff Beach Encinitas, CA

Hampton Inn by Hilton Cardiff Beach Encinitas, CA

3 out of 5
Save 100% on your flight
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to San Diego (SAN)
Stay at this 3-star business-friendly hotel in Cardiff-by-the-Sea. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Moonlight State Beach and Del Mar Racetrack are located nearby.
Hyatt Vacation Club at The Welk, San Diego Area

Hyatt Vacation Club at The Welk, San Diego Area

3.5 out of 5
Lawrence Welk Resort Village
Save 100% on your flight
per person
Aug 7 - Aug 11
found 19 hours ago
Roundtrip flight included
Orlando (MCO) to San Diego (SAN)
Book a stay at this spa hotel in Escondido. Enjoy free parking, 8 outdoor pools, and a full-service spa. Our guests praise the pool and the clean rooms in our reviews. Popular attractions The Oaks Course and Cal-a-vie are located nearby.
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
Mission Valley
per person
Jul 25 - Jul 29
found 17 hours ago
Roundtrip non-stop flight included
Cincinnati (CVG) to San Diego (SAN)
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.

3-4 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Motel San Diego - In San Diego (Pacific Beach)

Motel San Diego - In San Diego (Pacific Beach)

2 out of 5
Pacific Beach
per person
Aug 7 - Aug 11
found 19 hours ago
Roundtrip flight included
Orlando (MCO) to San Diego (SAN)
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
per person
Jul 31 - Aug 4
found 1 day ago
Roundtrip flight included
Orlando (MCO) to San Diego (SAN)
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4 out of 5
Downtown San Diego
per person
Jul 31 - Aug 4
found 1 day ago
Roundtrip flight included
Orlando (MCO) to San Diego (SAN)
Coronado Beach Resort

Coronado Beach Resort

3 out of 5
Historic Downtown Coronado
Save 100% on your flight
per person
Aug 4 - Aug 7
found 16 hours ago
Roundtrip flight included
Phoenix (PHX) to San Diego (SAN)

5-7 Night Vacations in Otay Mesa

Price found within the past 48 hours. Click for updated prices.
Motel San Diego - In San Diego (Pacific Beach)

Motel San Diego - In San Diego (Pacific Beach)

2 out of 5
Pacific Beach
Save 100% on your flight
per person
Aug 2 - Aug 7
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to San Diego (SAN)
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
per person
Jul 31 - Aug 5
found 1 day ago
Roundtrip non-stop flight included
Orlando (MCO) to San Diego (SAN)
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4 out of 5
Downtown San Diego
Save 100% on your flight
per person
Jul 31 - Aug 5
found 1 day ago
Roundtrip non-stop flight included
Orlando (MCO) to San Diego (SAN)
Hotel Avenida - Oceanside Camp Pendleton

Hotel Avenida - Oceanside Camp Pendleton

2.5 out of 5
Loma Alta
Save 100% on your flight
per person
Jul 26 - Aug 2
found 21 hours ago
Roundtrip flight included
Phoenix (PHX) to San Diego (SAN)

Cheap Hotel Deals in Otay Mesa

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
Marriott Marquis San Diego Marina
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
Manchester Grand Hyatt San Diego
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S, San Diego, CA
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
Kings Inn San Diego
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The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
The Dana on Mission Bay
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
Handlery Hotel
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr, San Diego, CA
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful ...
DoubleTree by Hilton Hotel San Diego - Mission Valley
Comfort Inn Sea World Area

Comfort Inn Sea World Area

3.5 out of 5
3880 Greenwood St, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Comfort Inn Sea World Area
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy, San Diego, CA
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
Embassy Suites by Hilton San Diego Bay Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Tue, Jul 22 - Wed, Jul 30
SFO
San Francisco Intl.
SAN
San Diego Intl.
$57 Roundtrip, found 2 hours ago
$57
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Jul 22 from San Francisco Intl. to San Diego Intl., returning Wed, Jul 30, priced at $57 found 2 hours ago
Spirit Airlines
Wed, Jul 9 - Tue, Jul 15
DFW
Dallas-Fort Worth Intl.
SAN
San Diego Intl.
$126 Roundtrip, found 12 hours ago
$126
Roundtrip
found 12 hours ago
Select Spirit Airlines flight, departing Wed, Jul 9 from Dallas-Fort Worth Intl. to San Diego Intl., returning Tue, Jul 15, priced at $126 found 12 hours ago
Spirit Airlines
Sat, Jul 19 - Mon, Jul 21
PDX
Portland Intl.
SAN
San Diego Intl.
$140 Roundtrip, found 12 hours ago
$140
Roundtrip
found 12 hours ago
Select Spirit Airlines flight, departing Sat, Jul 19 from Portland Intl. to San Diego Intl., returning Mon, Jul 21, priced at $140 found 12 hours ago
Frontier Airlines
Sat, Jul 12 - Wed, Jul 16
DEN
Denver Intl.
SAN
San Diego Intl.
$148 Roundtrip, found 1 day ago
$148
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Jul 12 from Denver Intl. to San Diego Intl., returning Wed, Jul 16, priced at $148 found 1 day ago