Search Deals onOtay Mesa Vacation Packages
Otay Mesa Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

The Sofia Hotel
Downtown San Diego
Save 100% on your flight
Price was $820, price is now $544 per person
$544
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Stay at this 3.5-star historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.

Southern California Beach Club
Townsite
Price was $970, price is now $698 per person
$698
per person
Oct 12 - Oct 16
found 1 day ago
Roundtrip non-stop flight included
Denver (DEN) to San Diego (SAN)
Stay at this 3-star beach condo in Oceanside. Enjoy free WiFi, a beach locale, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions LEGOLAND® California and Oceanside Beach are located nearby.

Sand Castle Inn
Save 100% on your flight
Price was $1,395, price is now $920 per person
$920
per person
Oct 15 - Oct 23
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to San Diego (SAN)
Book a stay at this beach motel in Imperial Beach. Enjoy free WiFi, free parking, and laundry facilities. Our guests praise the helpful staff in our reviews. Popular attractions San Diego Bay and Las Americas Premium Outlets are located nearby.

Margaritaville Hotel San Diego Gaslamp Quarter
Downtown San Diego
Save 100% on your flight
Price was $1,077, price is now $716 per person
$716
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Stay at this 4-star hotel in San Diego. Enjoy a rooftop terrace, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.

Hotel La Jolla, Curio Collection by Hilton
La Jolla Shores
Save 100% on your flight
Price was $1,313, price is now $895 per person
$895
per person
Oct 18 - Oct 25
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Stay at this 4-star business-friendly hotel in La Jolla. Enjoy room service, a fitness center, and wired Internet (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Bay and Mission Beach are located nearby.

Coronado Beach Resort
Historic Downtown Coronado
Save 100% on your flight
Price was $848, price is now $579 per person
$579
per person
Oct 27 - Oct 31
found 14 hours ago
Roundtrip flight included
Chicago (ORD) to San Diego (SAN)
Stay at this 3-star condo in Coronado. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Hotel del Coronado and Petco Park are located nearby.

Alma San Diego Downtown, a Tribute Portfolio Hotel
Downtown San Diego
Save 100% on your flight
Price was $919, price is now $634 per person
$634
per person
Oct 9 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Diego (SAN)
Stay at this 4-star boutique hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.

La Jolla Cove Suites
Village of La Jolla
Save 100% on your flight
Price was $1,093, price is now $760 per person
$760
per person
Oct 16 - Oct 21
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
Book a stay at this beach hotel in La Jolla. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
3-4 Night Vacations in Otay Mesa
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in Otay Mesa
Price found within the past 48 hours. Click for updated prices.



Cheap Hotel Deals in Otay Mesa

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue, San Diego, CA
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Save an average of 15% on thousands of hotels when you're signed in

Palihotel San Diego Gaslamp Quarter
830 Sixth Avenue, San Diego, CA
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in ...

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...

Hard Rock Hotel San Diego
207 5th Ave, San Diego, CA
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our ...

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Stay at this 3.5-star hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular ...

Bay Club Hotel & Marina
2131 Shelter Island Dr, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Mon, Nov 10 - Wed, Nov 12
SFO
San Francisco Intl.
SAN
San Diego Intl.
$77 Roundtrip, found 17 hours ago
$77
Roundtrip
found 17 hours ago

Tue, Oct 7 - Sat, Oct 11
DEN
Denver Intl.
SAN
San Diego Intl.
$92 Roundtrip, found 1 day ago
$92
Roundtrip
found 1 day ago

Sat, Nov 1 - Sat, Nov 8
ORD
O'Hare Intl.
SAN
San Diego Intl.
$139 Roundtrip, found 6 days ago
$139
Roundtrip
found 6 days ago

Thu, Sep 25 - Tue, Oct 7
PDX
Portland Intl.
SAN
San Diego Intl.
$156 Roundtrip, found 5 days ago
$156
Roundtrip
found 5 days ago
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