Search Deals onSan Francisco Vacation Packages
Photo by Hideki Yamagata
San Francisco Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
![Hotel Panamonte](https://images.trvl-media.com/lodging/2000000/1750000/1745200/1745151/ffc5eed9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Hotel Panamonte
per person
Mar 24 - Mar 28
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3.5-star hotel in Jaramillo. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Boquete Community Players Theater and Events Center and Church of San Juan Bautista are located nearby.
![Residencia Natural](https://images.trvl-media.com/lodging/19000000/18280000/18277300/18277244/53ecf2c5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Residencia Natural
per person
Mar 17 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3-star beach aparthotel in Bastimentos. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Bastimentos National Marine Park and Playa Larga are located nearby.
![La Coralina Island House](https://images.trvl-media.com/lodging/70000000/69940000/69932900/69932803/24d177ee_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
La Coralina Island House
Save 100% on your flight
per person
Apr 1 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3.5-star beach hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Paunch Beach and Tortuga Beach are located nearby.
![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/4b0d48d5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Villa Botero By Casa Mojito B&B
per person
Apr 1 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3-star golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.
![Punta Caracol Acqua Lodge](https://images.trvl-media.com/lodging/1000000/890000/889800/889730/a34ec6e6_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Punta Caracol Acqua Lodge
Punta Caracol
Save 100% on your flight
per person
Apr 1 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3.5-star beach lodge in Bocas del Toro. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Gruta Cave and Institute for Tropical Ecology & Conservation - Bocas del Toro Biological Station are located nearby.
![Los Establos Boutique Resort- All Inclusive](https://images.trvl-media.com/lodging/7000000/6350000/6349300/6349280/c1d21be0_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Los Establos Boutique Resort- All Inclusive
Save 100% on your flight
per person
Apr 1 - Apr 8
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 4.5-star luxury hotel in Jaramillo. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions El Explorador and Boquete Community Players Theater and Events Center are located nearby.
![NAYARA Bocas del Toro](https://images.trvl-media.com/lodging/52000000/51310000/51300100/51300004/e08f5b2e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
NAYARA Bocas del Toro
Save 100% on your flight
per person
Apr 1 - Apr 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 4-star spa hotel in Isla Frangipani. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews.
![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/fcdec2d2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Dreams Playa Bonita Panama - All Inclusive
per person
Apr 5 - Apr 9
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Amador Causeway and Albrook Shopping Mall are located nearby.
3-4 Night Vacations in San Francisco
Price found within the past 48 hours. Click for updated prices.
![Residencia Natural](https://images.trvl-media.com/lodging/19000000/18280000/18277300/18277244/53ecf2c5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
![Hotel Panamonte](https://images.trvl-media.com/lodging/2000000/1750000/1745200/1745151/ffc5eed9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/fcdec2d2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
5-7 Night Vacations in San Francisco
Price found within the past 48 hours. Click for updated prices.
![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/4b0d48d5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
![Residencia Natural](https://images.trvl-media.com/lodging/19000000/18280000/18277300/18277244/53ecf2c5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
![La Coralina Island House](https://images.trvl-media.com/lodging/70000000/69940000/69932900/69932803/24d177ee_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Cheap Hotel Deals in San Francisco
![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/05c7fc0a_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/d8f830ce_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/91ef3398_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
JW Marriott Panama
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
Save an average of 15% on thousands of hotels when you're signed in
![Ramada Plaza By Wyndham Panama Punta Pacífica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/54467206_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Ramada Plaza By Wyndham Panama Punta Pacífica
Via Israel y Calle 71, San Francisco, Panama City, Panama
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
![Residence Inn by Marriott Panama City](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/2b453483_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Residence Inn by Marriott Panama City
CALLE RAMON H JURADO EDIFICO P, Panama City
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Megapolis Hotel Panamá
Avenida Balboa, Panama City
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/b89a4dbb_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Las Americas Golden Tower Panama
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/39819ccf_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
![Copa](http://images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif)
Tue, Feb 18 - Tue, Feb 18
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$245 Roundtrip, found 5 days ago
$245
Roundtrip
found 5 days ago
![American Airlines](http://images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif)
Wed, Sep 10 - Mon, Sep 15
MIA
Miami Intl.
PTY
Tocumen Intl.
$319 Roundtrip, found 5 hours ago
$319
Roundtrip
found 5 hours ago
![Delta](http://images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif)
Sat, Feb 22 - Sun, Mar 2
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
![Delta](http://images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif)
Fri, Mar 21 - Tue, Mar 25
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$431 Roundtrip, found 6 hours ago
$431
Roundtrip
found 6 hours ago
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