Search Deals onSan Francisco Vacation Packages
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San Francisco Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Casa Madre Tierra
per person
May 22 - May 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3-star hotel in Los Llanitos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Valley of Square Trees and Square Trees Nature Trail are located nearby.

Central Hotel Panama Casco Viejo
Casco Viejo
per person
May 22 - May 26
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

La Coralina Island House
per person
May 22 - May 27
found 24 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3.5-star beach hotel in Bocas del Toro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Paunch Beach and Tortuga Beach are located nearby.

The Gray by Wynwood House
Bella Vista
Save 100% on your flight
per person
May 24 - May 29
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Hotel La Compania, in the Unbound Collection by Hyatt
Casco Viejo
per person
May 22 - May 26
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Round the point Bungalow
per person
May 31 - Jun 7
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 3-star cabin in Bastimentos. Enjoy free WiFi, dry cleaning or laundry services, and balconies or patios. Popular attractions Bastimento-Bocas del Toro Ferry Terminal and Up in the Hill Organic Coffee Farm are located nearby.

La Loma Jungle Lodge
per person
May 22 - May 27
found 24 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Book a stay at this spa lodge in Bastimentos. Enjoy free breakfast, a full-service spa, and daily housekeeping. Popular attractions Nivida Bat Cave and Playa Larga are located nearby.

Dreams Playa Bonita Panama - All Inclusive
per person
May 22 - May 26
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
3-4 Night Vacations in San Francisco
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in San Francisco
Price found within the past 48 hours. Click for updated prices.



Cheap Hotel Deals in San Francisco

JW Marriott Panama
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...

Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
Save an average of 15% on thousands of hotels when you're signed in

Decapolis Hotel Panama City
Avenida Balboa Con Multicentro, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...

Ramada Plaza By Wyndham Panama Punta Pacífica
Via Israel y Calle 71, San Francisco, Panama City, Panama
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...

Megapolis Hotel Panamá
Avenida Balboa, Panama City
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Las Americas Golden Tower Panama
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...

Residence Inn by Marriott Panama City
CALLE RAMON H JURADO EDIFICO P, Panama City
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Fri, May 2 - Sat, May 3
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$232 Roundtrip, found 5 days ago
$232
Roundtrip
found 5 days ago

Wed, May 7 - Wed, May 14
EWR
Newark Liberty Intl. Airport
PTY
Tocumen Intl.
$260 Roundtrip, found 1 day ago
$260
Roundtrip
found 1 day ago

Wed, May 7 - Sat, May 10
MIA
Miami Intl.
PTY
Tocumen Intl.
$283 Roundtrip, found 6 days ago
$283
Roundtrip
found 6 days ago

Tue, Oct 7 - Mon, Oct 20
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$363 Roundtrip, found 2 hours ago
$363
Roundtrip
found 2 hours ago
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