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4 Star Hotels in Southwest Houston

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Featured 4 Star Southwest Houston Hotels

Blossom Hotel Houston
4 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min walk from MD Anderson Cancer Center
The price is $171 per night from Dec 29 to Dec 30
$171
includes taxes & fees
Dec 29 - Dec 30
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
Blossom Hotel Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $119 per night from Dec 29 to Dec 30
$119
includes taxes & fees
Dec 29 - Dec 30
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel Houston - Greenway Plaza
4 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min drive from MD Anderson Cancer Center
The price is $108 per night from Dec 15 to Dec 16
$108
includes taxes & fees
Dec 15 - Dec 16
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
DoubleTree by Hilton Hotel Houston - Greenway Plaza
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Hyatt Regency Houston/Galleria
4 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from MD Anderson Cancer Center
The price is $178 per night from Dec 15 to Dec 16
$178
includes taxes & fees
Dec 15 - Dec 16
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Hyatt Regency Houston/Galleria
The Westin Galleria Houston
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 5 min drive from MD Anderson Cancer Center
The price is $280 per night from Dec 6 to Dec 7
$280
includes taxes & fees
Dec 6 - Dec 7
Book a stay at this golf hotel in Houston. Enjoy free parking, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
The Westin Galleria Houston
Omni Houston Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 9 min drive from MD Anderson Cancer Center
The price is $180 per night from Dec 21 to Dec 22
$180
includes taxes & fees
Dec 21 - Dec 22
Book a stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa, and 3 bars/lounges. Our guests praise the helpful staff and the property ...
Omni Houston Hotel
The Chifley Houston, Tapestry Collection by Hilton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $174 per night from Dec 3 to Dec 4
$174
includes taxes & fees
Dec 3 - Dec 4
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise ...
The Chifley Houston, Tapestry Collection by Hilton
The Royal Sonesta Houston Galleria
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $235 per night from Dec 14 to Dec 15
$235
includes taxes & fees
Dec 14 - Dec 15
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
The Royal Sonesta Houston Galleria
InterContinental Houston, an IHG Hotel
4 out of 5
Fully refundable
  • 2 min walk from MD Anderson Cancer Center
The price is $179 per night from Dec 28 to Dec 29
$179
includes taxes & fees
Dec 28 - Dec 29
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
InterContinental Houston, an IHG Hotel
The Westin Oaks Houston at the Galleria
4 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min drive from MD Anderson Cancer Center
The price is $270 per night from Dec 6 to Dec 7
$270
includes taxes & fees
Dec 6 - Dec 7
Stay at this 4-star business-friendly hotel in Houston. Enjoy free parking, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful staff ...
The Westin Oaks Houston at the Galleria
The Westin Houston Medical Center/Museum District
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from MD Anderson Cancer Center
The price is $189 per night from Dec 8 to Dec 9
$189
includes taxes & fees
Dec 8 - Dec 9
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour health club. Our guests praise the helpful ...
The Westin Houston Medical Center/Museum District
Hilton Houston Post Oak by the Galleria
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from MD Anderson Cancer Center
The price is $164 per night from Dec 1 to Dec 2
$164
includes taxes & fees
Dec 1 - Dec 2
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton Houston Post Oak by the Galleria
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Southwest Houston

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Southwest Houston for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Southwest Houston as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Southwest Houston 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Southwest Houston starting at $108 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Southwest Houston 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.