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Featured 5 Star Florida Keys Hotels
5-Star Hotel in Florida Keys
It’s time. No more meh motels and so-so stays. This vacation it’s all about living it up, and that starts with a great hotel. You want first-class service and award-winning restaurants. Well, let us introduce you to a 5-star hotel in Florida Keys.
So nice you’ll blink twice
What makes a hotel worthy of supreme star-age? For starters, the service has to be top-notch and personalized. These hotels often have 24-hour room service, a welcome gift upon your arrival, and help you with your bags—even if you travel light.
Are they nicer? Heck yeah, they are! Most 5-star hotels have jaw-dropping aesthetics that give an authentic feel of class. And we’re not talking about that faux-gold soap dish your Aunt Tilda puts out for the guests—it’s the real deal.
Stars in your eyes
Are 5-stars hotels worth it? If you like the finer things in life, then yes, they sure are. But we also know you’re the type that likes to get your caviar on a fish stick budget. We’re right there with you, and that is why we make it easy to find the best 5-star hotel in Florida Keys for you. Sort by:
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Price: Want to live large, but keep that budget balanced? We got you. We have 5-star hotels starting at $246.
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Amenities: Florida Keys skyline view? Maybe a heated indoor pool? Looking for a Michelin-star restaurant? Search for the hotels that have the amenities you desire.
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Hotwire Hot Rate: We’ll tell you the name of the hotel after you book, and you might just save a ton.
When you’re looking for the top 5-star hotels in Florida Keys—but don’t want to pay top dollar—let us help you out. You can get that posh palace of your dreams, and have money left to take on Florida Keys your way.
Popular Florida Keys Hotels
- Isla Bella Beach Resort & Spa
- Cheeca Lodge & Spa
- Marina Del Mar Resort and Marina
- Hawks Cay Resort
- Baker's Cay Resort Key Largo, Curio Collection by Hilton
- Waterside Suites & Marina
- Playa Largo Resort & Spa, Autograph Collection
- Holiday Inn Key Largo, an IHG Hotel
- Amara Cay Resort
- Chesapeake Beach Resort
- Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
- Lime Tree Bay Resort
Top Attractions in Florida Keys
- Hotels near Duval Street (43.42 mi)
- Hotels near Mallory Square (43.63 mi)
- Hotels near Smathers Beach (41.98 mi)
- Hotels near Southernmost Point (43.4 mi)
- Hotels near Sombrero Beach (8.9 mi)
- Hotels near Ernest Hemingway Home and Museum (43.45 mi)
- Hotels near Key West Golf Club (39.43 mi)
- Hotels near John Pennekamp Coral Reef State Park (52.95 mi)
- Hotels near Fort Zachary Taylor Historic State Park (43.99 mi)
- Hotels near South Beach (43.27 mi)
- Hotels near Jimmy Johnson's Big Chill (49.59 mi)
- Hotels near Biscayne National Park (78.11 mi)
- Hotels near Clarence S. Higgs Memorial Beach Park (42.68 mi)
- Hotels near Seven Mile Bridge (6.71 mi)
- Hotels near Stock Island Yacht Club & Marina (38.84 mi)
- Hotels near Baker's Cay Resort Beach (47.15 mi)
- Hotels near Harry S. Truman Little White House (43.66 mi)
- Hotels near Key West Lighthouse and Keeper's Quarters Museum (43.46 mi)
- Hotels near Anne's Beach (26.77 mi)
- Hotels near Key West Butterfly and Nature Conservatory (43.32 mi)
Nearby Cities
- Miami Beach Hotels (94.1 mi)
- Key West Hotels (43.43 mi)
- Key Largo Hotels (49.6 mi)
- Marathon Hotels (7.87 mi)
- Islamorada Hotels (34.7 mi)
- Doral Hotels (86.68 mi)
- Key Colony Beach Hotels (10.6 mi)
- Coral Gables Hotels (86.62 mi)
- Florida City Hotels (61.97 mi)
- Summerland Key Hotels (20.01 mi)
- Miami Springs Hotels (89.28 mi)
- Tavernier Hotels (43.22 mi)
More Accommodation Options in Florida Keys
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Car Rentals Near Florida Keys
- Car rentals in Miami Beach
- Car rentals in Key West
- Car rentals in Key Largo
- Car rentals in Marathon
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- Car rentals in Key Colony Beach
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- Car rentals in Summerland Key
- Car rentals in Miami Springs
- Car rentals in Tavernier
- Car rentals in Key Biscayne
- Car rentals in Big Pine Key
- Car rentals in Homestead
- Car rentals in Long Key