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Hotels in Florida Keys

Choose from 8235 Florida Keys Hotel Deals

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

5 out of 5
1 Knights Key Boulevard Marathon FL
  • 2 hours drive from Duval Street
Book a stay at this luxury hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
9.2/10 Wonderful! (1,302 reviews)
"Truly a unique resort within the keys. It’s located such that there are many things to do nearby, or you can stay on the property and get anything you need. Staff were very friendly and responded to your questions and requests. The gated property provides seclusion which is sometimes hard to find ..."

Reviewed on Nov 12, 2026

Isla Bella Beach Resort & Spa
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
  • 3 hours drive from Duval Street
Book a stay at this beach resort in Long Key. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,598 reviews)
"The room was nice, the bed was comfortable, and the views were beautiful. The beach area wasn't what we hoped for. We would have loved to have more access to the ocean. We also wanted more bottled water for the room and was told we had to bring our empty bottles and refill them in the office. Room ..."

Reviewed on Nov 12, 2026

Lime Tree Bay Resort
Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

3 out of 5
13201 Overseas Hwy Marathon FL
  • 2 hours drive from Duval Street
Book a stay at this business-friendly hotel in Marathon. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the breakfast and the restaurant ...
Fairfield Inn & Suites by Marriott Marathon Florida Keys
Kingsail Resort

Kingsail Resort

2 out of 5
7050 Overseas Highway Marathon FL
  • 2 hours drive from Duval Street
Stay at this motel in Marathon. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Kingsail Resort
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
  • 2 hours drive from Duval Street
Book a stay at this luxury hotel in Marathon. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Hawks Cay Resort
Parmer's Resort

Parmer's Resort

2.5 out of 5
565 Barry Avenue Summerland Key FL
  • 1 hour drive from Duval Street
Book a stay at this beach motel in Summerland Key. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Parmer's Resort
Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys

3 out of 5
2146 Overseas Hwy Marathon FL
  • 2 hours drive from Duval Street
Book a stay at this beach hotel in Marathon. Enjoy free WiFi, 2 outdoor pools, and a beach locale. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,001 reviews)
"Property looks rundown. No air in the hall ways. Room very outdated. The front clerk was extremely rude. Will not go back."

Reviewed on Nov 12, 2026

Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys
Rainbow Bend Resort

Rainbow Bend Resort

2.5 out of 5
57784 Overseas Hwy Marathon FL
  • 2 hours drive from Duval Street
Book a stay at this beach hotel in Marathon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
8.2/10 Very Good! (1,000 reviews)
"just what we needed for couple nights stay"

Reviewed on Nov 12, 2026

Rainbow Bend Resort
Coconut Cay Resort & Marina

Coconut Cay Resort & Marina

3 out of 5
7196 Overseas Highway Marathon FL
  • 2 hours drive from Duval Street
Stay at this hotel in Marathon. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Coconut Cay Resort & Marina
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

4 out of 5
2600 Overseas Hwy Marathon FL
  • 2 hours drive from Duval Street
Book a stay at this beach hotel in Marathon. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
Tranquility Bay Beachfront Hotel and Resort
Captain Pips Marina & Hideaway

Captain Pips Marina & Hideaway

3 out of 5
1480 Overseas Hwy Marathon FL
  • 2 hours drive from Duval Street
Stay at this hotel in Marathon. Enjoy free WiFi, a marina, and free bicycles on site. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,000 reviews)
"Awesome Relaxing Private !!"

Reviewed on Nov 10, 2026

Captain Pips Marina & Hideaway
Old Wooden Bridge Resort and Marina

Old Wooden Bridge Resort and Marina

2.5 out of 5
1791 Bogie Drive Big Pine Key FL
  • 1 hour drive from Duval Street
Stay at this cottage in Big Pine Key. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions Bahia ...
8.6/10 Excellent! (384 reviews)
"The location could be wonderful, but the unit we were checked into had an active mold problem and was not the one originally booked. The staff was unhelpful about correcting the situation. My party had to split up and find alternative lodging."

Reviewed on Nov 12, 2026

Old Wooden Bridge Resort and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Florida Keys

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Florida Keys.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Florida Keys’s 8,235 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $94. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Florida Keys hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Florida Keys. No matter your reason for visiting Florida Keys, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Florida Keys hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Florida Keys for as low as $94.

How many hotels are there in Florida Keys?

With over 8,235 hotels in Florida Keys, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $94.

How to find cheap car rentals in Florida Keys?

Finding a cheap car rental deal in Florida Keys is as easy as scoring cheap hotels in Florida Keys. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.