Adults Only Resorts & Hotels in
Florida Keys

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Tonight Nov 17 - Nov 18Next weekend Nov 22 - Nov 24

Featured Florida Keys Adults Only Resorts & Hotels

The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is $179 per night from Nov 18 to Nov 19
$179
includes taxes & fees
Nov 18 - Nov 19
The Southernmost Inn - Adults Only
Paradise Inn Key West - Adults Only
Paradise Inn Key West - Adults Only
3.5 out of 5
819 Simonton Street, Key West, FL
The price is $269 per night from Nov 18 to Nov 19
$269
includes taxes & fees
Nov 18 - Nov 19
Paradise Inn Key West - Adults Only
Heron House - Adult Only
Heron House - Adult Only
3.5 out of 5
512 Simonton St, Key West, FL
The price is $263 per night from Nov 18 to Nov 19
$263
includes taxes & fees
Nov 18 - Nov 19
Heron House - Adult Only
The Mansion on the Sea - Southernmost House in the USA
The Mansion on the Sea - Southernmost House in the USA
3 out of 5
1400 Duval Street, Key West, FL
The price is $536 per night from Nov 18 to Nov 19
$536
includes taxes & fees
Nov 18 - Nov 19
The Mansion on the Sea - Southernmost House in the USA
Heron House Court - Adult Only
Heron House Court - Adult Only
3 out of 5
412 Frances St, Key West, FL
The price is $191 per night from Nov 18 to Nov 19
$191
includes taxes & fees
Nov 18 - Nov 19
Heron House Court - Adult Only
The Cabana Inn Key West - Adults Only
The Cabana Inn Key West - Adults Only
3 out of 5
413 Applerouth Lane, Key West, FL
The price is $224 per night from Nov 20 to Nov 21
$224
includes taxes & fees
Nov 20 - Nov 21
The Cabana Inn Key West - Adults Only
Alexander's Gay and Lesbian Guesthouse - Adults Only
Alexander's Gay and Lesbian Guesthouse - Adults Only
3.5 out of 5
1118 Fleming St, Key West, FL
Alexander's Gay and Lesbian Guesthouse - Adults Only
Casa Morada
Casa Morada
3.5 out of 5
136 Madeira Road, Islamorada, FL
The price is $521 per night from Nov 24 to Nov 25
$521
includes taxes & fees
Nov 24 - Nov 25
Casa Morada
Ridley House - Key West Historic Inns
Ridley House - Key West Historic Inns
3.5 out of 5
601 Caroline St, Key West, FL
The price is $401 per night from Nov 18 to Nov 19
$401
includes taxes & fees
Nov 18 - Nov 19
Ridley House - Key West Historic Inns
Duval House
Duval House
3 out of 5
815 Duval St, Key West, FL
The price is $167 per night from Nov 19 to Nov 20
$167
includes taxes & fees
Nov 19 - Nov 20
Duval House
H2O Suites - Adults Only
H2O Suites - Adults Only
3.5 out of 5
1212 Simonton Street, Key West, FL
The price is $494 per night from Nov 18 to Nov 19
$494
includes taxes & fees
Nov 18 - Nov 19
H2O Suites - Adults Only
L'Habitation Guest House
L'Habitation Guest House
2.5 out of 5
408 Eaton Street, Key West, FL
The price is $153 per night from Nov 20 to Nov 21
$153
includes taxes & fees
Nov 20 - Nov 21
L'Habitation Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Florida Keys

United States of America is a city that has a lot going on, but you have your sights set on Florida Keys. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Florida Keys has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Florida Keys hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of United States of America so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Florida Keys underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Florida Keys city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Florida Keys cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Florida Keys at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $153
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Florida Keys hotel you want, book it, and never look back. Because your great escape is ahead of you.