Search for Cheap Deals on
5 Star Hotels in Santa Maria Novella

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!

Featured 5 Star Santa Maria Novella Hotels

Sina Villa Medici, Autograph Collection
5 out of 5
Fully refundableReserve now, pay when you stay
  • 10 min walk from Piazza di Santa Maria Novella
The price is $384 per night from Mar 8 to Mar 9
$384
includes taxes & fees
Mar 8 - Mar 9
Stay at this 5-star luxury hotel in Florence. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Popular attractions Historic Centre of Florence and ...
Sina Villa Medici, Autograph Collection
The St. Regis Florence
5 out of 5
Fully refundableReserve now, pay when you stay
  • 6 min walk from Piazza di Santa Maria Novella
The price is $795 per night from Mar 6 to Mar 7
$795
includes taxes & fees
Mar 6 - Mar 7
Stay at this 5-star luxury hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff and the property ...
The St. Regis Florence
Anglo American Hotel Florence, Curio Collection by Hilton
5 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min walk from Piazza di Santa Maria Novella
The price is $264 per night from Mar 11 to Mar 12
$264
includes taxes & fees
Mar 11 - Mar 12
Stay at this 5-star luxury hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Historic Centre of Florence ...
Anglo American Hotel Florence, Curio Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Dimora Palanca Boutique & SPA
5 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min walk from Piazza di Santa Maria Novella
Stay at this 5-star luxury hotel in Florence. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Popular attractions Historic Centre of Florence ...
Get rates
Dimora Palanca Boutique & SPA
The Westin Excelsior, Florence
5 out of 5
  • 5 min walk from Piazza di Santa Maria Novella
Stay at this 5-star luxury hotel in Florence. Enjoy free WiFi, 2 bars/lounges, and a rooftop terrace. Our guests praise the property condition in our reviews. ...
Get rates
The Westin Excelsior, Florence
Don't see what you're looking for?
See all available properties in Santa Maria Novella
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.