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Hotels in Canalou

Choose from 24 Canalou Hotel Deals

Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
  • 7 hours drive from Mississippi River
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,008 reviews)
"We were travelling through and were pleasantly surprised at how well maintained the hotel was. Also breakfast was great with eggs and biscuits and gravy. Would definitely stay again."

Reviewed on Jul 8, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
  • 7 hours drive from Mississippi River
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,000 reviews)
"Clean and conveniently located near restaurants. The free breakfast was enjoyable, and the happy hour was a delightful treat."

Reviewed on Jul 8, 2025

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
  • 7 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
"I will be staying here again"

Reviewed on Jul 7, 2025

Pear Tree Inn Sikeston
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
  • 7 hours drive from Mississippi River
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (361 reviews)
"Not bad"

Reviewed on Jul 6, 2025

Hampton Inn Sikeston
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 7 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
Keep up the renovations
"This hotel looked like an old apartment building renovation into a hotel with much wrk in progress. Decent stay. Spacious. Very minimal breakfast offerings. The geese outside sure left messes everywhere but the greeting cat was a nice touch"

Reviewed on Jun 28, 2025

Days Inn and Suites by Wyndham Sikeston
Fairfield by Marriott Inn & Suites Sikeston
Fairfield by Marriott Inn & Suites Sikeston
2.5 out of 5
1239 Commerce Drive, Sikeston, MO
  • 7 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.8/10 Exceptional! (10 reviews)
"Clean and comfortable"

Reviewed on Jun 25, 2025

Fairfield by Marriott Inn & Suites Sikeston
Dexter Inn
Dexter Inn
2.5 out of 5
1807 W Business US Highway 60, Dexter, MO
  • 8 hours drive from Mississippi River
Stay at this hotel in Dexter. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions The ...
6.8/10 (305 reviews)
"I always stay here when I’m in town. Great place"

Reviewed on Jun 19, 2025

Dexter Inn
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
2.5 out of 5
109 Matthews Ln, Sikeston, MO
  • 7 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Sikeston. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (266 reviews)
"It was cool"

Reviewed on Jun 24, 2025

Comfort Inn & Suites Sikeston I-55
Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
  • 7 hours drive from Mississippi River
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Central Park and Sikeston Depot Museum are located ...
7/10 Good! (96 reviews)
"Good but WiFi weak"

Reviewed on Apr 10, 2025

Country Yard Inn and Suite
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
  • 7 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (410 reviews)
"Overall a nice hotel, everything was clean and maintained, staff was helpful. We didn't realize there were no towels in the pool room til we were all wet, but made do with a couple from the gym next door😅 Breakfast was a great selection of hot and cold food options"

Reviewed on Jun 30, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
Travelodge by Wyndham Dexter
Travelodge by Wyndham Dexter
2 out of 5
1608 E Business US 60, Dexter, MO
  • 8 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Dexter. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Heritage House and Keller ...
7.4/10 Good! (361 reviews)
"A nice property just off the beaten path."

Reviewed on Jul 6, 2025

Travelodge by Wyndham Dexter
 OYO Malden Airport Inn
OYO Malden Airport Inn
2.5 out of 5
2989 North Douglass Street, Malden, MO
  • 8 hours drive from Mississippi River
Stay at this hotel in Malden. Enjoy free WiFi, free parking, and room service. Popular attraction Morris State Park is located nearby.
7.2/10 Good! (53 reviews)
"Awesome"

Reviewed on May 31, 2025

OYO Malden Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Canalou

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Canalou.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Canalou’s 24 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $64. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Canalou hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Canalou. No matter your reason for visiting Canalou, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Canalou hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Canalou?

With over 24 hotels in Canalou, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

How to find cheap car rentals in Canalou?

Finding a cheap car rental deal in Canalou is as easy as scoring cheap hotels in Canalou. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.