Search for Cheap Deals on
Luxury Hotels in Central West End

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!

Featured Luxury Central West End

The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. Louis
4.5 out of 5
212 N Kingshighway, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
The Royal Sonesta Chase Park Plaza St. Louis
Holiday Inn Express St Louis - Central West End, an IHG Hotel
Holiday Inn Express St Louis - Central West End, an IHG Hotel
2.5 out of 5
4630 Lindell, St. Louis, MO
Fully refundable
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
Holiday Inn Express St Louis - Central West End, an IHG Hotel
DoubleTree by Hilton St. Louis Forest Park
DoubleTree by Hilton St. Louis Forest Park
4 out of 5
4550 Forest Park Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
DoubleTree by Hilton St. Louis Forest Park
See all 1,911 properties in Central West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.