Hotels Near
Grand Center

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Featured Grand Center Hotels

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (1,065 reviews)
"As you enter, you check on the 12 th floor… the roof top bar was nice"

Reviewed on Jun 6, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
 White House at Grand Central

White House at Grand Central

3.5 out of 5
3805 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
Stay at this apartment in St. Louis. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions St. Louis Union Station and Busch Stadium are located ...
8.4/10 Very Good! (136 reviews)
"Well it was 6/10. The place is right in the middle of SLU and a great neighborhood. You could park for free and walk the 4 blocks but we took the chance and parked right in front of the hotel with like all big cities have sold their souls to parking companies for every usable space with 6 inches ..."

Reviewed on Jun 3, 2026

White House at Grand Central
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,097 reviews)
"Valet Parking was horrible. We thought we made the right choice for only $10.00 more, to use valet. The day to leave was a chaotic experience. One worker to retrieve cars and it took one hour. So unorganized and understaffed for a Saturday. We felt like we were in Valet jail and would never see our ..."

Reviewed on Jun 6, 2026

Hyatt Regency St. Louis at The Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,340 reviews)
"We enjoyed our overnight stay and breakfast very much! The room was clean and the beds were comfortable. Breakfast was very good, with a variety of choices."

Reviewed on Jun 6, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,227 reviews)
"We were pleasantly surprised by this hotel. The breakfast buffet was above and beyond our expectations with made to order waffles and omelettes, fresh fruit, and a wide variety of options. The room was spacious and clean. There were some great dinner options nearby. The game room and pool were under ..."

Reviewed on Jun 6, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (2,005 reviews)
"Mrs. Doris is amazing and the stay was wonderful overall, except that the pool was closed and that was one reason we chose this hotel. We took the shuttle next door to the Cardinal's game and highly recommend it."

Reviewed on Jun 6, 2026

Pear Tree Inn St. Louis Near Union Station
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (3,000 reviews)
"Nice clean hotel, with friendly helpful staff."

Reviewed on Jun 6, 2026

Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,482 reviews)
"Clean. Breakfast was very good! We missed the happy hour but I’m sure it would have been just as good. Will stay again."

Reviewed on Jun 6, 2026

Drury Plaza Hotel St. Louis at the Arch
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

3.5 out of 5
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,294 reviews)
"I was blindsided by a $30 per day parking fee at check-in and elevators were hectic and the waits were long which I had trouble with as a wheelchair user but outside of that, my husband and I had a nice stay."

Reviewed on Jun 5, 2026

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (1,210 reviews)
"Location and it was really beautiful for the price."

Reviewed on Jun 6, 2026

Live by Loews - St.Louis
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,221 reviews)
"The shuttles cost an extra fee. No free breakfast. Rude staff. Dirty rooms."

Reviewed on Jun 5, 2026

Hollywood Casino & Hotel St. Louis
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

4 out of 5
1 S Broadway St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy 3 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the clean rooms in our ...
7.6/10 Good! (1,158 reviews)
"Staff was excellent and accommodating. Bistro food outstanding. Ideal location."

Reviewed on Jun 5, 2026

Hilton St. Louis at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Grand Center

St. Louis is a city that has a lot going on, but you have your sights set on Grand Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Grand Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Grand Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Grand Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Grand Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Grand Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Grand Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $106
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Grand Center hotel you want, book it, and never look back. Because your great escape is ahead of you.