Hotels Near
Grand Center

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Featured Grand Center Hotels

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (1,067 reviews)
"Really unique place and wondefull rooftop"

Reviewed on Jun 7, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
 White House at Grand Central

White House at Grand Central

3.5 out of 5
3805 Lindell Blvd St. Louis MO
Stay at this apartment in St. Louis. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions St. Louis Union Station and Busch Stadium are located ...
8.4/10 Very Good! (137 reviews)
"Well it was 6/10. The place is right in the middle of SLU and a great neighborhood. You could park for free and walk the 4 blocks but we took the chance and parked right in front of the hotel with like all big cities have sold their souls to parking companies for every usable space with 6 inches ..."

Reviewed on Jun 3, 2026

White House at Grand Central
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,101 reviews)
"Great time was had!! Loved the bar restaurant and meeting new people there!!!"

Reviewed on Jun 10, 2026

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (2,021 reviews)
"Great breakfast and beds super comfortable! Only complaint is bathroom sink is very small and very little space to set stuff!"

Reviewed on Jun 10, 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,249 reviews)
"We enjoyed the shower as it was digital and easy to use The hotel is dated and our room had peeling paint and a musty smell."

Reviewed on Jun 10, 2026

Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,228 reviews)
"The staff was very kind, but we kept getting locked off our floor and they continued to do it. And we were supposed to get the rodeo room, which included a couch with hideabed a bathtub separate from ice shower, and we got none of the above the bathroom was still dirty.We paid a hundred and sixty ..."

Reviewed on Jun 8, 2026

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,352 reviews)
"Room had no blanket go front desk guy couldn't get into housekeeping and didn't want help so had no blanket all night one worst motel experiences I've ever had"

Reviewed on Jun 10, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (3,000 reviews)
"We weren’t aware but there is a $50 deposit even if you prepay for the room, they had good staff and a good breakfast however our AC leaked"

Reviewed on Jun 10, 2026

Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,499 reviews)
"The hotel is very well maintained, just on the dated side."

Reviewed on Jun 10, 2026

Drury Plaza Hotel St. Louis at the Arch
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (1,221 reviews)
"Always just wonderful. We stay here often. There is no better way to experience Busch Stadium than Live by Loews."

Reviewed on Jun 10, 2026

Live by Loews - St.Louis
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

3.5 out of 5
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,302 reviews)
"Clean room, great breakfast, and very friendly staff. Only downside was a lot of the plugs didn’t work in the room"

Reviewed on Jun 9, 2026

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

4 out of 5
1 S Broadway St. Louis MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy 3 restaurants, 3 bars/lounges, and a rooftop terrace. Our guests praise the clean rooms in our ...
7.6/10 Good! (1,160 reviews)
"There are no microwaves on this property. The rooms are outdated and it’s very busy on the"

Reviewed on Jun 10, 2026

Hilton St. Louis at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Grand Center

St. Louis is a city that has a lot going on, but you have your sights set on Grand Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Grand Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Grand Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Grand Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Grand Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Grand Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Grand Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $106
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Grand Center hotel you want, book it, and never look back. Because your great escape is ahead of you.