Hotels Near
Grand Center

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Featured Grand Center Hotels

Angad Arts Hotel
Angad Arts Hotel
4 out of 5
3550 Samuel Shepard Drive, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
8.6/10 Excellent! (1,040 reviews)
"Love the art and rooftop bar!!"

Reviewed on May 16, 2025

Angad Arts Hotel
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,561 reviews)
Not Sleeping Well
"Our room was underneath the 8th floor swimming pool which made noise all night. They offered to move us, but we should not have been put there initially. we did not want to move everything for one night. This disturbed our sleep: perhaps we were put there because we are older."

Reviewed on May 16, 2025

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,665 reviews)
"Overall great stay!"

Reviewed on May 15, 2025

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,910 reviews)
It was better than average.
"The room was nice, comfortable and clean. The bed was comfortable. The barn door for the bathroom was a bit odd. Dinner for 4 in their Smokehoue BBQ Restaurant we very mediocre and took far too long to serve. With a bill of over $150 and us all agreeing that the mac and cheese on the side was the ..."

Reviewed on May 14, 2025

Hollywood Casino & Hotel St. Louis
Drury Inn & Suites St. Louis Union Station
Drury Inn & Suites St. Louis Union Station
3 out of 5
201 S 20th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,120 reviews)
"We loved the dining options, drinks and popcorn. Staff was great!!! and very helpful. Our only complaint was the vomit by the hot tub and the brown color of the pool bottom. We did notify front desk that there was vomit and the sent someone right away to clean it up and close the hot tub. That was ..."

Reviewed on May 15, 2025

Drury Inn & Suites St. Louis Union Station
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,573 reviews)
"Nice property"

Reviewed on May 17, 2025

Pear Tree Inn St. Louis Airport
River City Casino & Hotel
River City Casino & Hotel
4 out of 5
777 River City Casino Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,203 reviews)
"Rooms were clean and the beds and shower was excellent"

Reviewed on May 14, 2025

River City Casino & Hotel
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,960 reviews)
"Could use some updating but overall very happy with the stay. Price point was great on the executive suite."

Reviewed on May 16, 2025

Clayton Plaza Hotel & Extended Stay
Hilton St. Louis Airport
Hilton St. Louis Airport
3.5 out of 5
10330 Natural Bridge Rd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.4/10 Good! (1,011 reviews)
"The most amazing things were the shuttle from the airport and I could walk on safe sidewalks to Hertz"

Reviewed on May 15, 2025

Hilton St. Louis Airport
Best Western St. Louis-Kirkwood Route 66
Best Western St. Louis-Kirkwood Route 66
2.5 out of 5
1200 S Kirkwood Road, Kirkwood, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Kirkwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,151 reviews)
Safety bars
"Shower needs safety bars. Breakfast is skimpy and is not replenished so everyone has something to eat."

Reviewed on May 13, 2025

Best Western St. Louis-Kirkwood Route 66
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4 out of 5
421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
8.6/10 Excellent! (1,011 reviews)
"Great location!"

Reviewed on May 12, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 out of 5
333 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,054 reviews)
"Good stay"

Reviewed on May 14, 2025

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Grand Center

St. Louis is a city that has a lot going on, but you have your sights set on Grand Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Grand Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Grand Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Grand Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Grand Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Grand Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Grand Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Grand Center hotel you want, book it, and never look back. Because your great escape is ahead of you.