Hotels Near
Central West End

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Featured Central West End Hotels

Aloft St. Louis Cortex
Aloft St. Louis Cortex
3 out of 5
4245 Duncan Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (613 reviews)
"We are handicapped and our every need was attended to."

Reviewed on Dec 22, 2024

Aloft St. Louis Cortex
 The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. Louis
4.5 out of 5
212 N Kingshighway, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,001 reviews)
"Being close to the park is great. Will come back in the summer"

Reviewed on Dec 20, 2024

The Royal Sonesta Chase Park Plaza St. Louis
DoubleTree by Hilton St. Louis Forest Park
DoubleTree by Hilton St. Louis Forest Park
4 out of 5
4550 Forest Park Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,001 reviews)
Returning 10 year guest
"We have stayed at this hotel many times in the last 10 years because of the closeness and convenience to BJH. It’s always clean and comfortable. I really miss the days when it wasn’t operated by Hilton, however, because there were no added charges for parking or breakfast. Coffee, juice, popcorn ..."

Reviewed on Dec 9, 2024

DoubleTree by Hilton St. Louis Forest Park
AC Hotel St. Louis Central West End
AC Hotel St. Louis Central West End
4 out of 5
215 YORK AVENUE, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (545 reviews)
"Nice"

Reviewed on Dec 15, 2024

AC Hotel St. Louis Central West End
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,542 reviews)
So happy
"Enjoyed my quiet night sleep in a clean environment"

Reviewed on Dec 20, 2024

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,748 reviews)
75th birthday celebration
"The hotel was fine. Our rooms were clean and comfortable. The staff in the hotel and in the casino were excellent and always helpful. My only issues are that there is no bell desk staff. You are required to leave your id to get a luggage cart to transport your belongings yourself. Also the tv remote ..."

Reviewed on Dec 22, 2024

Hollywood Casino & Hotel St. Louis
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,342 reviews)
"Great place"

Reviewed on Dec 19, 2024

Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,923 reviews)
"The room was very clean and the breakfast was wonderful."

Reviewed on Dec 22, 2024

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4.5 out of 5
1528 Locust street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (856 reviews)
21C is a present to yourself for a stay anytime!
"21C amazing as always!! l look for a 21C first anytime l travel for an overnight stay l don't feel like l'm in a hotel for the night, but instead feel transported to an experience that brings beauty and comfort to my stay with their attention to details and onsite art gallery; and provides delicious ..."

Reviewed on Dec 21, 2024

21C Museum Hotel St Louis
The Last Hotel
The Last Hotel
4.5 out of 5
1501 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
7.8/10 Good! (1,156 reviews)
"We came back from the dome race late and we were ready for showers… we noticed that no one had serviced our room and had to go get towels at 1am. I left a tip out for guest services before we left for the day as well."

Reviewed on Dec 9, 2024

The Last Hotel
Renaissance St. Louis Airport Hotel
Renaissance St. Louis Airport Hotel
4 out of 5
9801 Natural Bridge Road, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.2/10 Very Good! (1,005 reviews)
"Nice showers and good rooms"

Reviewed on Dec 21, 2024

Renaissance St. Louis Airport Hotel
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 out of 5
333 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,005 reviews)
"The room had a fantastic view of the Arch but the street out front was a virtual race track most of the night."

Reviewed on Dec 20, 2024

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Central West End

St. Louis is a city that has a lot going on, but you have your sights set on Central West End. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Central West End has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Central West End hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Central West End underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Central West End city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Central West End cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Central West End at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $111
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Central West End hotel you want, book it, and never look back. Because your great escape is ahead of you.