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Carlisle

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Carlisle Flights as Low as $75

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Aug 21 - Fri, Aug 22
DEN
Denver Intl.
DSM
Des Moines Intl.
$75 Roundtrip, found 2 days ago
$75
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Denver Intl. to Des Moines Intl., returning Fri, Aug 22, priced at $75 found 2 days ago
Frontier Airlines
Mon, Aug 18 - Thu, Aug 21
DEN
Denver Intl.
DSM
Des Moines Intl.
$87 Roundtrip, found 1 day ago
$87
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Aug 18 from Denver Intl. to Des Moines Intl., returning Thu, Aug 21, priced at $87 found 1 day ago
Frontier Airlines
Fri, Aug 22 - Sun, Aug 31
DEN
Denver Intl.
DSM
Des Moines Intl.
$90 Roundtrip, found 2 days ago
$90
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Aug 22 from Denver Intl. to Des Moines Intl., returning Sun, Aug 31, priced at $90 found 2 days ago
United
Sun, Aug 24 - Sun, Aug 31
DEN
Denver Intl.
DSM
Des Moines Intl.
$140 Roundtrip, found 2 days ago
$140
Roundtrip
found 2 days ago
Select United flight, departing Sun, Aug 24 from Denver Intl. to Des Moines Intl., returning Sun, Aug 31, priced at $140 found 2 days ago
American Airlines
Wed, Aug 20 - Sat, Aug 23
DEN
Denver Intl.
DSM
Des Moines Intl.
$179 Roundtrip, found 3 days ago
$179
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Aug 20 from Denver Intl. to Des Moines Intl., returning Sat, Aug 23, priced at $179 found 3 days ago
American Airlines
Wed, Aug 20 - Mon, Aug 25
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$180 Roundtrip, found 12 hours ago
$180
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Wed, Aug 20 from Sky Harbor Intl. to Des Moines Intl., returning Mon, Aug 25, priced at $180 found 12 hours ago
American Airlines
Wed, Aug 27 - Sun, Aug 31
ORD
O'Hare Intl.
DSM
Des Moines Intl.
$189 Roundtrip, found 12 hours ago
$189
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Wed, Aug 27 from O'Hare Intl. to Des Moines Intl., returning Sun, Aug 31, priced at $189 found 12 hours ago
Delta
Sat, Sep 13 - Sun, Sep 14
DEN
Denver Intl.
DSM
Des Moines Intl.
$197 Roundtrip, found 1 day ago
$197
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Sep 13 from Denver Intl. to Des Moines Intl., returning Sun, Sep 14, priced at $197 found 1 day ago
Bargain Flight
Wed, Oct 1 - Wed, Oct 8
JAX
Jacksonville Intl.
DSM
Des Moines Intl.
$250 Roundtrip, found 2 days ago
$250
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Wed, Oct 1 from Jacksonville Intl. to Des Moines Intl., returning Wed, Oct 8, priced at $250 found 2 days ago
Delta
Thu, Aug 28 - Tue, Sep 9
MSO
Missoula Intl.
DSM
Des Moines Intl.
$259 Roundtrip, found 9 hours ago
$259
Roundtrip
found 9 hours ago
Select Delta flight, departing Thu, Aug 28 from Missoula Intl. to Des Moines Intl., returning Tue, Sep 9, priced at $259 found 9 hours ago
Delta
Thu, Nov 27 - Wed, Dec 3
AUS
Austin-Bergstrom Intl.
DSM
Des Moines Intl.
$267 Roundtrip, found 1 day ago
$267
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Nov 27 from Austin-Bergstrom Intl. to Des Moines Intl., returning Wed, Dec 3, priced at $267 found 1 day ago
American Airlines
Tue, Sep 2 - Wed, Sep 10
AMA
Rick Husband Amarillo Intl.
DSM
Des Moines Intl.
$312 Roundtrip, found 10 hours ago
$312
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Sep 2 from Rick Husband Amarillo Intl. to Des Moines Intl., returning Wed, Sep 10, priced at $312 found 10 hours ago
United
Sat, Nov 1 - Tue, Nov 4
GTF
Great Falls Intl.
DSM
Des Moines Intl.
$314 Roundtrip, found 9 hours ago
$314
Roundtrip
found 9 hours ago
Select United flight, departing Sat, Nov 1 from Great Falls Intl. to Des Moines Intl., returning Tue, Nov 4, priced at $314 found 9 hours ago
Bargain Flight
Tue, Aug 5 - Mon, Aug 18
SAT
San Antonio Intl.
DSM
Des Moines Intl.
$387 Roundtrip, found 14 hours ago
$387
Roundtrip
found 14 hours ago
Select Bargain Flight flight, departing Tue, Aug 5 from San Antonio Intl. to Des Moines Intl., returning Mon, Aug 18, priced at $387 found 14 hours ago
Delta
Wed, Jul 30 - Tue, Aug 5
AGS
Augusta Regional
DSM
Des Moines Intl.
$398 Roundtrip, found 14 hours ago
$398
Roundtrip
found 14 hours ago
Select Delta flight, departing Wed, Jul 30 from Augusta Regional to Des Moines Intl., returning Tue, Aug 5, priced at $398 found 14 hours ago
Delta
Tue, Jul 29 - Sun, Aug 3
CLE
Hopkins Intl.
DSM
Des Moines Intl.
$546 Roundtrip, found 8 hours ago
$546
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Jul 29 from Hopkins Intl. to Des Moines Intl., returning Sun, Aug 3, priced at $546 found 8 hours ago

Cheap Flights to Carlisle

Fall in love at first flight with your vacation to Carlisle by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Carlisle on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Carlisle, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Carlisle

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Carlisle with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Carlisle?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Carlisle are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Carlisle?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Carlisle.

What airport is best to fly into Carlisle?

When you’re planning your trip to Carlisle, convenience is the name of the game. Luckily, Carlisle Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Carlisle must-do list.

How much are flights to Carlisle?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Carlisle on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $75, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Carlisle?

The trick to saving a stack of cash on your flight to Carlisle? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $75 right now, why wait?

Carlisle Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$74

Last Minute Hotel Deals in Carlisle

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St, Des Moines, IA
Stay at this 4.5-star luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,025 reviews)
Awesome for a couple’s night
"We only stayed one night but loved this hotel. Neat decor, comfy bed and lots of space in our king room."

Reviewed on Jul 25, 2025

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Hotel Fort Des Moines, Curio Collection by Hilton
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,572 reviews)
"Loved the bed and pillows, and convenient parking. I did not like the noise. I had very noisy guests as neighbors. I could hear everything in the hallway, nextdoor rooms and rooms above, etc....and people were up all hours of the night. I could actually hear the neighboring guest take a leak in the ..."

Reviewed on Jul 26, 2025

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Days Inn & Suites by Wyndham Des Moines Airport
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave, Des Moines, IA
Stay at this 3-star hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (1,015 reviews)
"Nice and clean. Property well cared for. Breakfast wasn’t free, but quite enjoyable."

Reviewed on Jul 25, 2025

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Holiday Inn Downtown - Mercy Area by IHG
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (462 reviews)
"This location is in a nice area where we felt safe. The room was clean and an excellent value for the price. The property is very pet friendly. We would definitely stay again."

Reviewed on Jul 23, 2025

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Motel 6 West Des Moines, IA
Days Inn by Wyndham West Des Moines / Clive

Days Inn by Wyndham West Des Moines / Clive

2 out of 5
1600 NW 114th St, Clive, IA
Book a stay at this business-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Jordan Creek Town Center and Clive ...
6/10 (1,009 reviews)
"The location for us was good, the room was clean, and what I expected, outside the room was already little dirty and not kept up well. Lots of cigarette butts on the back steps and other flooring in the hallways was not kept up as well as it could’ve been. Price was good! Would have liked a little ..."

Reviewed on Jul 20, 2025

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Days Inn by Wyndham West Des Moines / Clive
Sonesta Essential Des Moines

Sonesta Essential Des Moines

2 out of 5
4755 Merle Hay Road, Des Moines, IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.2/10 Good! (1,014 reviews)
"It was clean and breakfast was good."

Reviewed on Jul 26, 2025

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Sonesta Essential Des Moines
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,768 reviews)
Cabin not in the woods
"This place is amazing. I’ve never stayed in a place quite like this. I got one of the cottage themed rooms and it was amazing. It was extremely comfortable (except for the pillows but it’s rare to get good pillows in a hotel). It was so spacious it felt like the room kept going. The room I booked ..."

Reviewed on Jul 25, 2025

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Stoney Creek Hotel Des Moines - Johnston
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave., Des Moines, IA
Stay at this 3-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (912 reviews)
"My husband and I are very leary of hotel stays and was pleasantly surprised and happy with our accommodations. Our dog loved it too."

Reviewed on Jul 24, 2025

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Home2 Suites by Hilton Des Moines at Drake University
See all 794 properties in Carlisle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.