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Durham

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Durham Flights as Low as $115

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Sat, Feb 14 - Tue, Feb 24
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$115 Roundtrip, found 18 hours ago
$115
Roundtrip
found 18 hours ago
Select Breeze Airways flight, departing Sat, Feb 14 from Orlando Intl. to Portsmouth Intl., returning Tue, Feb 24, priced at $115 found 18 hours ago
Breeze Airways
Sat, Feb 14 - Tue, Feb 24
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$118 Roundtrip, found 18 hours ago
$118
Roundtrip
found 18 hours ago
Select Breeze Airways flight, departing Sat, Feb 14 from Orlando Intl. to Portsmouth Intl., returning Tue, Feb 24, priced at $118 found 18 hours ago
Breeze Airways
Sat, Feb 14 - Tue, Feb 24
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$120 Roundtrip, found 1 day ago
$120
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sat, Feb 14 from Orlando Intl. to Portsmouth Intl., returning Tue, Feb 24, priced at $120 found 1 day ago
Breeze Airways
Sat, Feb 14 - Tue, Feb 24
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$125 Roundtrip, found 18 hours ago
$125
Roundtrip
found 18 hours ago
Select Breeze Airways flight, departing Sat, Feb 14 from Orlando Intl. to Portsmouth Intl., returning Tue, Feb 24, priced at $125 found 18 hours ago
Breeze Airways
Sat, Feb 14 - Tue, Feb 24
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$128 Roundtrip, found 18 hours ago
$128
Roundtrip
found 18 hours ago
Select Breeze Airways flight, departing Sat, Feb 14 from Orlando Intl. to Portsmouth Intl., returning Tue, Feb 24, priced at $128 found 18 hours ago
Breeze Airways
Sat, Feb 14 - Tue, Feb 24
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$135 Roundtrip, found 12 hours ago
$135
Roundtrip
found 12 hours ago
Select Breeze Airways flight, departing Sat, Feb 14 from Orlando Intl. to Portsmouth Intl., returning Tue, Feb 24, priced at $135 found 12 hours ago
Breeze Airways
Sat, Feb 14 - Tue, Feb 24
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$138 Roundtrip, found 12 hours ago
$138
Roundtrip
found 12 hours ago
Select Breeze Airways flight, departing Sat, Feb 14 from Orlando Intl. to Portsmouth Intl., returning Tue, Feb 24, priced at $138 found 12 hours ago
Breeze Airways
Thu, Feb 5 - Sun, Feb 8
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$140 Roundtrip, found 1 day ago
$140
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Thu, Feb 5 from Orlando Intl. to Portsmouth Intl., returning Sun, Feb 8, priced at $140 found 1 day ago
American Airlines
Wed, Apr 1 - Wed, Apr 8
MCO
Orlando Intl.
MHT
Manchester-Boston Regional
$148 Roundtrip, found 19 hours ago
$148
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Apr 1 from Orlando Intl. to Manchester-Boston Regional, returning Wed, Apr 8, priced at $148 found 19 hours ago
JetBlue Airways
Sat, Apr 4 - Mon, Apr 6
MCO
Orlando Intl.
MHT
Manchester-Boston Regional
$182 Roundtrip, found 1 day ago
$182
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Sat, Apr 4 from Orlando Intl. to Manchester-Boston Regional, returning Mon, Apr 6, priced at $182 found 1 day ago
United
Thu, Mar 12 - Mon, Mar 16
MCO
Orlando Intl.
MHT
Manchester-Boston Regional
$211 Roundtrip, found 1 day ago
$211
Roundtrip
found 1 day ago
Select United flight, departing Thu, Mar 12 from Orlando Intl. to Manchester-Boston Regional, returning Mon, Mar 16, priced at $211 found 1 day ago
Bargain Flight
Tue, Jun 16 - Tue, Jun 23
PHL
Philadelphia Intl.
MHT
Manchester-Boston Regional
$218 Roundtrip, found 23 hours ago
$218
Roundtrip
found 23 hours ago
Select Bargain Flight flight, departing Tue, Jun 16 from Philadelphia Intl. to Manchester-Boston Regional, returning Tue, Jun 23, priced at $218 found 23 hours ago
American Airlines
Tue, Apr 7 - Tue, Apr 14
MCO
Orlando Intl.
MHT
Manchester-Boston Regional
$239 Roundtrip, found 22 hours ago
$239
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Apr 7 from Orlando Intl. to Manchester-Boston Regional, returning Tue, Apr 14, priced at $239 found 22 hours ago
American Airlines
Tue, Feb 24 - Wed, Feb 25
DTW
Detroit Metropolitan Wayne County
MHT
Manchester-Boston Regional
$376 Roundtrip, found 9 hours ago
$376
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Tue, Feb 24 from Detroit Metropolitan Wayne County to Manchester-Boston Regional, returning Wed, Feb 25, priced at $376 found 9 hours ago
American Airlines
Tue, Jun 16 - Tue, Jun 23
TTN
Mercer
MHT
Manchester-Boston Regional
$377 Roundtrip, found 23 hours ago
$377
Roundtrip
found 23 hours ago
Select American Airlines flight, departing Tue, Jun 16 from Mercer to Manchester-Boston Regional, returning Tue, Jun 23, priced at $377 found 23 hours ago
American Airlines
Sun, May 24 - Sat, May 30
XNA
Northwest Arkansas Regional
MHT
Manchester-Boston Regional
$461 Roundtrip, found 6 hours ago
$461
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sun, May 24 from Northwest Arkansas Regional to Manchester-Boston Regional, returning Sat, May 30, priced at $461 found 6 hours ago

Cheap Flights to Durham

Fall in love at first flight with your vacation to Durham by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Durham on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Durham, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Durham

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Durham with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the BOS airport.

What is the cheapest month to fly to Durham?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Durham are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Durham?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Durham.

What airport is best to fly into Durham?

When you’re planning your trip to Durham, convenience is the name of the game. Luckily, Durham Portsmouth Intl. Airport is nearby so you can deplane and get going on checking off everything on your Durham must-do list.

How much are flights to Durham?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Durham on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $115, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Durham?

The trick to saving a stack of cash on your flight to Durham? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $115 right now, why wait?

Durham Flight Information
Destination airport
Portsmouth Intl.
Destination airport IATA code
PSM
Roundtrip price
$115

Last Minute Hotel Deals in Durham

Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown

3 out of 5
23 Portwalk Pl Portsmouth NH
Book a stay at this business-friendly hotel in Portsmouth. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,095 reviews)
Good location, nice hotel in Portsmouth. Walkable to downtown... modern room decor very clean. Good breakfast choices and free coffee available all day.. Friendly staff. Note Parking is by Valet only at $45/night. Would stay again...

Reviewed on Feb 1, 2026

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Hampton Inn & Suites Portsmouth Downtown
Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown

3 out of 5
100 High St Portsmouth NH
Book a stay at this business-friendly hotel in Portsmouth. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (229 reviews)
Quick one night getaway! Everything was perfect!

Reviewed on Jan 25, 2026

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Hilton Garden Inn Portsmouth Downtown
Anchorage Inn and Resort

Anchorage Inn and Resort

3 out of 5
265 Long Beach Avenue York Beach ME
Book a stay at this beach hotel in York Beach. Enjoy free WiFi, free parking, and 2 indoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,062 reviews)
It was clean and close to the ocean.

Reviewed on Jan 22, 2026

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Anchorage Inn and Resort
Cliff House Maine

Cliff House Maine

4.5 out of 5
591 Shore Road Cape Neddick ME
Book a stay at this luxury resort in Cape Neddick. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the property ...
9.4/10 Exceptional! (1,001 reviews)
Nearly everything was perfect at this hotel. Quality of the facilities, friendly staff, good restaurants, beautiful spa, all of it. The only minor negative was that there was live music in the lobby that was a little too loud one day. The musician was great, but it made it a little tough to enjoy ...

Reviewed on Jan 31, 2026

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Cliff House Maine
Postcard Cabins Blake Brook, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Blake Brook, Outdoor Collection by Marriott Bonvoy

2 out of 5
76 Mountain Rd Epsom NH
Stay at this cabin in Epsom. Enjoy free parking, patios, and climate control. Popular attractions James Park and Epsom Public Library are located nearby.
9.6/10 Exceptional! (113 reviews)
Room was so clean, it had everything we needed inside.

Reviewed on Jan 25, 2026

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Postcard Cabins Blake Brook, Outdoor Collection by Marriott Bonvoy
Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG

Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG

3 out of 5
28 Mile Road Wells ME
Book a stay at this business-friendly hotel in Wells. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (591 reviews)
Clean room, comfy bed, friendly staff, good breakfast, convenient location

Reviewed on Jan 25, 2026

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Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG
Residence Inn by Marriott Portsmouth Downtown/ Waterfront

Residence Inn by Marriott Portsmouth Downtown/ Waterfront

3 out of 5
100 Deer Street Portsmouth NH
Book a stay at this business-friendly hotel in Portsmouth. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
9/10 Wonderful! (1,000 reviews)
The breakfast had all kinds of goodies. Oatmeal, with several toppings to choose from. The hot menu seems to change from day to day. We were there for a week, had eggs & bacon one day, then sausage patties and links the next. They surprised me on day 4 by having spinach quiche! Cereals, juice, breads, ...

Reviewed on Jan 7, 2026

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Residence Inn by Marriott Portsmouth Downtown/ Waterfront
Holiday Inn Express Hotel & Suites Seabrook by IHG

Holiday Inn Express Hotel & Suites Seabrook by IHG

2.5 out of 5
11 Rocks Rd Seabrook NH
Stay at this hotel in Seabrook. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,002 reviews)
Yes

Reviewed on Jan 22, 2026

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Holiday Inn Express Hotel & Suites Seabrook by IHG
See all 2,513 properties in Durham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.