Search Cheap Flights to
Durham

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Durham Flights as Low as $112

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Sat, Nov 7 - Sat, Nov 14
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$112 Roundtrip, found 5 days ago
$112
Roundtrip
found 5 days ago
Select Breeze Airways flight, departing Sat, Nov 7 from Orlando Intl. to Portsmouth Intl., returning Sat, Nov 14, priced at $112 found 5 days ago
Breeze Airways
Sat, Nov 7 - Sat, Nov 14
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$113 Roundtrip, found 5 days ago
$113
Roundtrip
found 5 days ago
Select Breeze Airways flight, departing Sat, Nov 7 from Orlando Intl. to Portsmouth Intl., returning Sat, Nov 14, priced at $113 found 5 days ago
Breeze Airways
Sat, Nov 7 - Sat, Nov 14
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$117 Roundtrip, found 2 days ago
$117
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Sat, Nov 7 from Orlando Intl. to Portsmouth Intl., returning Sat, Nov 14, priced at $117 found 2 days ago
Breeze Airways
Sat, Nov 7 - Sat, Nov 14
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$118 Roundtrip, found 2 days ago
$118
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Sat, Nov 7 from Orlando Intl. to Portsmouth Intl., returning Sat, Nov 14, priced at $118 found 2 days ago
Breeze Airways
Sat, Nov 7 - Sat, Nov 14
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$122 Roundtrip, found 2 hours ago
$122
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Sat, Nov 7 from Orlando Intl. to Portsmouth Intl., returning Sat, Nov 14, priced at $122 found 2 hours ago
Breeze Airways
Sat, Nov 7 - Sat, Nov 14
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$123 Roundtrip, found 2 hours ago
$123
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Sat, Nov 7 from Orlando Intl. to Portsmouth Intl., returning Sat, Nov 14, priced at $123 found 2 hours ago
Breeze Airways
Sat, Nov 7 - Sat, Nov 14
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$127 Roundtrip, found 2 hours ago
$127
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Sat, Nov 7 from Orlando Intl. to Portsmouth Intl., returning Sat, Nov 14, priced at $127 found 2 hours ago
Breeze Airways
Sat, Nov 7 - Sat, Nov 14
MCO
Orlando Intl.
PSM
Portsmouth Intl.
$128 Roundtrip, found 1 day ago
$128
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sat, Nov 7 from Orlando Intl. to Portsmouth Intl., returning Sat, Nov 14, priced at $128 found 1 day ago
Breeze Airways
Thu, Nov 19 - Sun, Dec 6
RDU
Raleigh - Durham Intl.
MHT
Manchester-Boston Regional
$152 Roundtrip, found 2 hours ago
$152
Roundtrip
found 2 hours ago
Select Breeze Airways flight, departing Thu, Nov 19 from Raleigh - Durham Intl. to Manchester-Boston Regional, returning Sun, Dec 6, priced at $152 found 2 hours ago
Breeze Airways
Thu, Nov 19 - Thu, Dec 10
RDU
Raleigh - Durham Intl.
PSM
Portsmouth Intl.
$152 Roundtrip, found 5 days ago
$152
Roundtrip
found 5 days ago
Select Breeze Airways flight, departing Thu, Nov 19 from Raleigh - Durham Intl. to Portsmouth Intl., returning Thu, Dec 10, priced at $152 found 5 days ago
Breeze Airways
Sat, Dec 5 - Wed, Dec 16
RSW
Southwest Florida Intl.
PSM
Portsmouth Intl.
$173 Roundtrip, found 20 hours ago
$173
Roundtrip
found 20 hours ago
Select Breeze Airways flight, departing Sat, Dec 5 from Southwest Florida Intl. to Portsmouth Intl., returning Wed, Dec 16, priced at $173 found 20 hours ago
Breeze Airways
Wed, Oct 28 - Sun, Nov 8
MCO
Orlando Intl.
MHT
Manchester-Boston Regional
$221 Roundtrip, just found
$221
Roundtrip
just found
Select Breeze Airways flight, departing Wed, Oct 28 from Orlando Intl. to Manchester-Boston Regional, returning Sun, Nov 8, priced at $221 just found
Southwest Airlines
Fri, Dec 11 - Mon, Dec 14
RSW
Southwest Florida Intl.
MHT
Manchester-Boston Regional
$246 Roundtrip, found 3 days ago
$246
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Fri, Dec 11 from Southwest Florida Intl. to Manchester-Boston Regional, returning Mon, Dec 14, priced at $246 found 3 days ago
American Airlines
Fri, Dec 11 - Mon, Dec 14
RSW
Southwest Florida Intl.
MHT
Manchester-Boston Regional
$311 Roundtrip, found 3 days ago
$311
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Dec 11 from Southwest Florida Intl. to Manchester-Boston Regional, returning Mon, Dec 14, priced at $311 found 3 days ago
United
Thu, Oct 15 - Mon, Oct 19
RDU
Raleigh - Durham Intl.
MHT
Manchester-Boston Regional
$350 Roundtrip, just found
$350
Roundtrip
just found
Select United flight, departing Thu, Oct 15 from Raleigh - Durham Intl. to Manchester-Boston Regional, returning Mon, Oct 19, priced at $350 just found
American Airlines
Tue, Oct 6 - Wed, Oct 14
LAX
Los Angeles Intl.
MHT
Manchester-Boston Regional
$472 Roundtrip, found 2 hours ago
$472
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Oct 6 from Los Angeles Intl. to Manchester-Boston Regional, returning Wed, Oct 14, priced at $472 found 2 hours ago

Cheap Flights to Durham

Fall in love at first flight with your vacation to Durham by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Durham on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Durham, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Durham

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Durham with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the BOS airport.

What is the cheapest month to fly to Durham?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Durham are in November, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Durham?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Durham.

What airport is best to fly into Durham?

When you’re planning your trip to Durham, convenience is the name of the game. Luckily, Durham Portsmouth Intl. Airport is nearby so you can deplane and get going on checking off everything on your Durham must-do list.

How much are flights to Durham?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Durham on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $112, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Durham?

The trick to saving a stack of cash on your flight to Durham? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $112 right now, why wait?

Durham Flight Information
Destination airport
Portsmouth Intl.
Destination airport IATA code
PSM
Roundtrip price
$111

Last Minute Hotel Deals in Durham

Quality Inn Portsmouth

Quality Inn Portsmouth

2.5 out of 5
1190 Lafayette Road Portsmouth NH
Stay at this hotel in Portsmouth. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,004 reviews)
"Staff was polite room was nice breakfast was good and the hot tub was realizing"

Reviewed on Sep 20, 2026

Get rates
Quality Inn Portsmouth
Ocean Sands at York Beach

Ocean Sands at York Beach

2 out of 5
277 Long Beach Avenue York Beach ME
Book a stay at this beach motel in York Beach. Enjoy an outdoor pool, parking (surcharge), and a garden. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (188 reviews)
"One night stay. Lovely staff, very clean, great mattress and across the street from the beach. Simple and perfect. Btw...powerful water pressure."

Reviewed on Sep 20, 2026

Get rates
Ocean Sands at York Beach
Ogunquit - The Milestone

Ogunquit - The Milestone

2 out of 5
687 Main Street Ogunquit ME
Book a stay at this business-friendly motel in Ogunquit. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,551 reviews)
"Place needs updates, painting, furnishing etc."

Reviewed on Sep 21, 2026

Get rates
Ogunquit - The Milestone
Ashworth by the Sea

Ashworth by the Sea

3 out of 5
295 Ocean Blvd Hampton NH
Book a stay at this beach hotel in Hampton. Enjoy 3 restaurants, a beach locale, and a rooftop terrace. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,417 reviews)
"It clean and modern enough. You can do better for the price . Also Valet doesn’t come in till 7am . So if have to leave before gat you are s.o.l. You have to use the valet you can not park your own car. But it’s a great location to the beach and the strip ."

Reviewed on Sep 20, 2026

Get rates
Ashworth by the Sea
Anchorage Inn and Resort

Anchorage Inn and Resort

3 out of 5
265 Long Beach Avenue York Beach ME
Book a stay at this beach hotel in York Beach. Enjoy free WiFi, free parking, and 2 indoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,258 reviews)
"The location was great right across from the beach & the beach is great wonderful walking beach. We were in the main building.The room was very small , fine for 2 . The bathroom so small if you sat on toilet you cookout the door . The carpet and the chairs were smelly & damp. The carpet in the hallway ..."

Reviewed on Sep 21, 2026

Get rates
Anchorage Inn and Resort
Hampton Inn Portsmouth Central

Hampton Inn Portsmouth Central

2.5 out of 5
131 DOW AVENUE Portsmouth NH
Book a stay at this business-friendly hotel in Portsmouth. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,006 reviews)
"Staff exceptionally helpful - thank you Carla and Peter. We had trouble with our baggage on the flight over and both went above and beyond to keep us informed of progress on delivery of our luggage (to the hotel)."

Reviewed on Sep 20, 2026

Get rates
Hampton Inn Portsmouth Central
Ogunquit River Inn & Suites

Ogunquit River Inn & Suites

3 out of 5
17 Post Road Ogunquit ME
Book a stay at this business-friendly hotel in Ogunquit. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,012 reviews)
"TV program selection"

Reviewed on Sep 20, 2026

Get rates
Ogunquit River Inn & Suites
Lamie's Inn and The Old Salt Restaurant

Lamie's Inn and The Old Salt Restaurant

3 out of 5
490 Lafayette Rd Hampton NH
Book a stay at this business-friendly inn in Hampton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful staff ...
9.4/10 Exceptional! (1,015 reviews)
"We were very happy with our stay. The room was clean, the staff helpful and the restaurant very accommodating with our late arrival."

Reviewed on Sep 21, 2026

Get rates
Lamie's Inn and The Old Salt Restaurant
See all 2,700 properties in Durham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.