Search Cheap Flights to
Seffner

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Seffner Flights as Low as $78

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Allegiant Air
Sun, Oct 11 - Thu, Oct 29
TTN
Mercer
PIE
St. Petersburg-Clearwater Intl.
$78 Roundtrip, found 18 hours ago
$78
Roundtrip
found 18 hours ago
Select Allegiant Air flight, departing Sun, Oct 11 from Mercer to St. Petersburg-Clearwater Intl., returning Thu, Oct 29, priced at $78 found 18 hours ago
Frontier Airlines
Sat, Oct 3 - Wed, Oct 21
DTW
Detroit Metropolitan Wayne County
TPA
Tampa Intl.
$80 Roundtrip, found 8 hours ago
$80
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Sat, Oct 3 from Detroit Metropolitan Wayne County to Tampa Intl., returning Wed, Oct 21, priced at $80 found 8 hours ago
Allegiant Air
Thu, Oct 1 - Thu, Oct 15
TTN
Mercer
PIE
St. Petersburg-Clearwater Intl.
$83 Roundtrip, found 3 days ago
$83
Roundtrip
found 3 days ago
Select Allegiant Air flight, departing Thu, Oct 1 from Mercer to St. Petersburg-Clearwater Intl., returning Thu, Oct 15, priced at $83 found 3 days ago
Allegiant Air
Thu, Aug 27 - Sun, Sep 6
TTN
Mercer
PIE
St. Petersburg-Clearwater Intl.
$88 Roundtrip, found 3 days ago
$88
Roundtrip
found 3 days ago
Select Allegiant Air flight, departing Thu, Aug 27 from Mercer to St. Petersburg-Clearwater Intl., returning Sun, Sep 6, priced at $88 found 3 days ago
Frontier Airlines
Tue, Sep 8 - Sat, Sep 26
DTW
Detroit Metropolitan Wayne County
TPA
Tampa Intl.
$92 Roundtrip, found 4 hours ago
$92
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Tue, Sep 8 from Detroit Metropolitan Wayne County to Tampa Intl., returning Sat, Sep 26, priced at $92 found 4 hours ago
Frontier Airlines
Mon, Oct 5 - Mon, Oct 12
TTN
Mercer
TPA
Tampa Intl.
$93 Roundtrip, found 12 hours ago
$93
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Mon, Oct 5 from Mercer to Tampa Intl., returning Mon, Oct 12, priced at $93 found 12 hours ago
Frontier Airlines
Sun, Aug 30 - Thu, Sep 3
CVG
Cincinnati - Northern Kentucky Intl.
TPA
Tampa Intl.
$93 Roundtrip, found 1 day ago
$93
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Aug 30 from Cincinnati - Northern Kentucky Intl. to Tampa Intl., returning Thu, Sep 3, priced at $93 found 1 day ago
Allegiant Air
Mon, Aug 31 - Wed, Sep 2
CVG
Cincinnati - Northern Kentucky Intl.
PIE
St. Petersburg-Clearwater Intl.
$96 Roundtrip, found 1 day ago
$96
Roundtrip
found 1 day ago
Select Allegiant Air flight, departing Mon, Aug 31 from Cincinnati - Northern Kentucky Intl. to St. Petersburg-Clearwater Intl., returning Wed, Sep 2, priced at $96 found 1 day ago
Allegiant Air
Mon, Aug 31 - Wed, Sep 2
CVG
Cincinnati - Northern Kentucky Intl.
PIE
St. Petersburg-Clearwater Intl.
$97 Roundtrip, found 3 days ago
$97
Roundtrip
found 3 days ago
Select Allegiant Air flight, departing Mon, Aug 31 from Cincinnati - Northern Kentucky Intl. to St. Petersburg-Clearwater Intl., returning Wed, Sep 2, priced at $97 found 3 days ago
Frontier Airlines
Mon, Aug 31 - Thu, Sep 3
CVG
Cincinnati - Northern Kentucky Intl.
TPA
Tampa Intl.
$99 Roundtrip, found 20 hours ago
$99
Roundtrip
found 20 hours ago
Select Frontier Airlines flight, departing Mon, Aug 31 from Cincinnati - Northern Kentucky Intl. to Tampa Intl., returning Thu, Sep 3, priced at $99 found 20 hours ago
Frontier Airlines
Tue, Sep 8 - Tue, Sep 15
EWR
Newark Liberty Intl. Airport
TPA
Tampa Intl.
$151 Roundtrip, just found
$151
Roundtrip
just found
Select Frontier Airlines flight, departing Tue, Sep 8 from Newark Liberty Intl. Airport to Tampa Intl., returning Tue, Sep 15, priced at $151 just found
United
Tue, Nov 3 - Tue, Nov 17
EWR
Newark Liberty Intl. Airport
TPA
Tampa Intl.
$177 Roundtrip, found 4 hours ago
$177
Roundtrip
found 4 hours ago
Select United flight, departing Tue, Nov 3 from Newark Liberty Intl. Airport to Tampa Intl., returning Tue, Nov 17, priced at $177 found 4 hours ago
American Airlines
Tue, Nov 3 - Tue, Nov 17
EWR
Newark Liberty Intl. Airport
TPA
Tampa Intl.
$197 Roundtrip, found 4 hours ago
$197
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Nov 3 from Newark Liberty Intl. Airport to Tampa Intl., returning Tue, Nov 17, priced at $197 found 4 hours ago
Delta
Wed, Sep 9 - Wed, Sep 23
DTW
Detroit Metropolitan Wayne County
TPA
Tampa Intl.
$199 Roundtrip, found 4 hours ago
$199
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, Sep 9 from Detroit Metropolitan Wayne County to Tampa Intl., returning Wed, Sep 23, priced at $199 found 4 hours ago
JetBlue Airways
Mon, Nov 2 - Thu, Nov 19
DTW
Detroit Metropolitan Wayne County
TPA
Tampa Intl.
$225 Roundtrip, found 23 hours ago
$225
Roundtrip
found 23 hours ago
Select JetBlue Airways flight, departing Mon, Nov 2 from Detroit Metropolitan Wayne County to Tampa Intl., returning Thu, Nov 19, priced at $225 found 23 hours ago
Breeze Airways
Sun, Sep 20 - Thu, Sep 24
TTN
Mercer
TPA
Tampa Intl.
$477 Roundtrip, found 1 day ago
$477
Roundtrip
found 1 day ago
Select Breeze Airways flight, departing Sun, Sep 20 from Mercer to Tampa Intl., returning Thu, Sep 24, priced at $477 found 1 day ago

Cheap Flights to Seffner

Fall in love at first flight with your vacation to Seffner by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seffner on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seffner, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seffner

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seffner with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the TPA airport.

What is the cheapest month to fly to Seffner?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seffner are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seffner?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Seffner.

What airport is best to fly into Seffner?

When you’re planning your trip to Seffner, convenience is the name of the game. Luckily, Seffner Peter O. Knight Airport is nearby so you can deplane and get going on checking off everything on your Seffner must-do list.

How much are flights to Seffner?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seffner on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $78, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seffner?

The trick to saving a stack of cash on your flight to Seffner? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $78 right now, why wait?

Seffner Flight Information
Destination airport
Tampa Intl.
Destination airport IATA code
TPA
Roundtrip price
$76

Last Minute Hotel Deals in Seffner

The Westin Tampa Bay

The Westin Tampa Bay

4 out of 5
7627 W Courtney Campbell Cswy Tampa FL
Book a stay at this beach hotel in Tampa. Enjoy free WiFi, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
Get rates
The Westin Tampa Bay
Four Points by Sheraton Suites Tampa Airport Westshore

Four Points by Sheraton Suites Tampa Airport Westshore

3 out of 5
4400 W Cypress St Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,088 reviews)
"I booked 7 days, walked into the stablisent and it was dusty everywhere you looked, the pond had a smell to it from it being dirty, all the outside plants, rails were full of layers of dust, walked into my room and found it to be just as disgusting. I don’t as there 30 minutes tops and had to walk ..."

Reviewed on Jul 30, 2026

Get rates
Four Points by Sheraton Suites Tampa Airport Westshore
Hotel Alba, Tapestry Collection by Hilton

Hotel Alba, Tapestry Collection by Hilton

4 out of 5
5303 W Kennedy Blvd Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Get rates
Hotel Alba, Tapestry Collection by Hilton
The Barrymore Hotel Tampa Riverwalk

The Barrymore Hotel Tampa Riverwalk

3 out of 5
111 W Fortune St Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the restaurant and the ...
8.6/10 Excellent! (2,721 reviews)
"The hotel was not the cleanest but it was close to some nice spots. The rooms were average but definitely need an upgrade."

Reviewed on Jul 30, 2026

Get rates
The Barrymore Hotel Tampa Riverwalk
Sailport Waterfront Suites

Sailport Waterfront Suites

3.5 out of 5
2506 N Rocky Point Dr Tampa FL
Book a stay at this business-friendly aparthotel in Tampa. Enjoy breakfast (surcharge), a fitness center, and a 24-hour front desk. Our guests praise the pool ...
Get rates
Sailport Waterfront Suites
OASIS BAY SUITES, Tampa, Busch Gardens, USF

OASIS BAY SUITES, Tampa, Busch Gardens, USF

3 out of 5
3001 University Center Dr Tampa FL
Stay at this hotel in Tampa. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Busch Gardens Tampa Bay and Seminole Hard Rock Casino Tampa ...
Get rates
OASIS BAY SUITES, Tampa, Busch Gardens, USF
DoubleTree by Hilton Tampa Rocky Point Waterfront

DoubleTree by Hilton Tampa Rocky Point Waterfront

4 out of 5
3050 N Rocky Point Dr W Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (1,004 reviews)
"Room need to be clean, good staff"

Reviewed on Jul 30, 2026

Get rates
DoubleTree by Hilton Tampa Rocky Point Waterfront
Grand Hyatt Tampa Bay

Grand Hyatt Tampa Bay

4 out of 5
2900 Bayport Drive Tampa FL
Book a stay at this business-friendly hotel in Tampa. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,284 reviews)
"When staying at the casitas be aware you will likely need to walk to the hotel for breakfast/food. No biggy but it does get hot. If you drive, your hotel card may not work for the hotel parking, and you will pay a fee for parking where the white tent is. The bay has a lot of mosquitos and we got ..."

Reviewed on Jul 30, 2026

Get rates
Grand Hyatt Tampa Bay
See all 5,010 properties in Seffner
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.