Search for Cheap Deals on
Hotels in Dona Ana

Choose from 335 Dona Ana Hotel Deals

Hotel Encanto de Las Cruces
Hotel Encanto de Las Cruces
3.5 out of 5
705 S Telshor Blvd, Las Cruces, NM
  • 5 min drive from New Mexico State University
Stay at this 3.5-star business-friendly hotel in Las Cruces. Enjoy 3 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (1,367 reviews)
Good comfortable stay with family and a kid
"Very good staff and friendly. Hotel rooms were clean."

Reviewed on Jul 8, 2025

Get rates
Hotel Encanto de Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces
3 out of 5
201 E University Avenue, I-10 Exit 142, Las Cruces, NM
  • 17 min walk from New Mexico State University
Stay at this 3-star spa hotel in Las Cruces. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,003 reviews)
"Very clean and very friendly"

Reviewed on Jul 8, 2025

Get rates
Ramada Hotel & Conference Center by Wyndham Las Cruces
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3 out of 5
1500 Hickory Dr, Las Cruces, NM
  • 5 min drive from New Mexico State University
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (2,163 reviews)
"Very clean"

Reviewed on Jul 13, 2025

Get rates
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Days Inn by Wyndham Las Cruces
Days Inn by Wyndham Las Cruces
2.5 out of 5
755 Avenida De Mesilla, Las Cruces, NM
  • 5 min drive from New Mexico State University
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,176 reviews)
Just fair.
"I stayed for a total of 27 days to help a local family member. Staff was friendly and the breakfast was adequate. My linens were changed only once during that time, but staff gave me more shampoo and soap when I asked for it. Location was convenient. It would have been helpful if their “business ..."

Reviewed on Jul 12, 2025

Get rates
Days Inn by Wyndham Las Cruces
Best Western Mission Inn
Best Western Mission Inn
2.5 out of 5
1765 S Main St, Las Cruces, NM
  • 27 min walk from New Mexico State University
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,180 reviews)
"Staff was excellent and rooms were very clean"

Reviewed on Jul 12, 2025

Get rates
Best Western Mission Inn
Comfort Suites Las Cruces I-25 North
Comfort Suites Las Cruces I-25 North
2.5 out of 5
236 N Telshor Blvd., Las Cruces, NM
  • 6 min drive from New Mexico State University
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,004 reviews)
"We love staying at the hotel the staff are very friendly and the rooms are amazing"

Reviewed on Jul 13, 2025

Get rates
Comfort Suites Las Cruces I-25 North
Drury Inn & Suites Las Cruces
Drury Inn & Suites Las Cruces
3 out of 5
1631 Hickory Loop, Las Cruces, NM
  • 5 min drive from New Mexico State University
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,007 reviews)
"Very quite and clean"

Reviewed on Jul 12, 2025

Get rates
Drury Inn & Suites Las Cruces
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
3 out of 5
790 Avenida De Mesilla, Las Cruces, NM
  • 5 min drive from New Mexico State University
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the clean rooms in our reviews. ...
5.6/10 (1,007 reviews)
"There was plenty of parking, the area was clean and convenient to fast food."

Reviewed on Jul 1, 2025

Get rates
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Comfort Suites University Las Cruces
Comfort Suites University Las Cruces
2.5 out of 5
2101 S Triviz Drive, Las Cruces, NM
  • 9 min walk from New Mexico State University
Book a stay at this golf hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (1,001 reviews)
"Breakfast was sparse. I went the first day about 830, which was close to the end but there was nothing available. And it looked like nothing had been refilled in a while. The second day it was so overpacked I couldn’t get anything either. I didn’t even try the third morning."

Reviewed on Jun 15, 2025

Get rates
Comfort Suites University Las Cruces
Springhill Suites By Marriott Las Cruces
Springhill Suites By Marriott Las Cruces
3 out of 5
1611 Hickory Loop, Las Cruces, NM
  • 5 min drive from New Mexico State University
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (888 reviews)
"This was a super nice hotel The staff were so kind and helpful. The breakfast was one of the best on our road trip. Would stay again for sure."

Reviewed on Jul 5, 2025

Get rates
Springhill Suites By Marriott Las Cruces
Hilton Garden Inn Las Cruces
Hilton Garden Inn Las Cruces
3 out of 5
2550 Don Roser Dr, Las Cruces, NM
  • 13 min walk from New Mexico State University
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,001 reviews)
"We are on a 1500 mile drive-thru out New Mexico, this was a good place to stop."

Reviewed on Jul 1, 2025

Get rates
Hilton Garden Inn Las Cruces
Comfort Inn & Suites Las Cruces Mesilla
Comfort Inn & Suites Las Cruces Mesilla
2.5 out of 5
1300 Avenida De Mesilla, Las Cruces, NM
  • 5 min drive from New Mexico State University
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,002 reviews)
Very pleasant stay
"Comfy bed, convenient access to room, nice breakfast. Desk clerk was very polite and welcoming."

Reviewed on Jul 8, 2025

Get rates
Comfort Inn & Suites Las Cruces Mesilla
See all 335 properties in Dona Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Dona Ana

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Dona Ana hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Dona Ana.

Choosing the right hotel in New Mexico has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Dona Ana’s 335 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Dona Ana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Dona Ana. No matter your reason for visiting Dona Ana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Dona Ana hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Dona Ana for as low as $59.

How many hotels are there in Dona Ana?

With over 335 hotels in Dona Ana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.

How to find cheap car rentals in Dona Ana?

Finding a cheap car rental deal in Dona Ana is as easy as scoring cheap hotels in Dona Ana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.