Search for Cheap Deals on
Hotels in Mesilla

Photo by Lane

Check Last Minute Mesilla Hotel Deals

Tonight Jan 11 - Jan 12Next weekend Jan 17 - Jan 19

Choose from 343 Mesilla Hotel Deals

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
2.5 out of 5
1500 Hickory Dr, Las Cruces, NM
  • 23 min walk from Mesillia Plaza
The price is $68 per night from Jan 19 to Jan 20
$68
includes taxes & fees
Jan 19 - Jan 20
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,936 reviews)
"For a brief, one night stay this property is what we needed. Bed was comfortable. Our room was cold and after talking with front desk, we were going to move to another room but then heat began to work. The family next to us got into argument that woke us at 1:15 in the morning. Fortunately, it carried ..."

Reviewed on Jan 10, 2025

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Hotel Encanto de Las Cruces
Hotel Encanto de Las Cruces
3.5 out of 5
705 S Telshor Blvd, Las Cruces, NM
  • 9 min drive from Mesillia Plaza
The price is $144 per night from Feb 2 to Feb 3
$144
includes taxes & fees
Feb 2 - Feb 3
Stay at this 3.5-star business-friendly hotel in Las Cruces. Enjoy 3 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the pool and the ...
8.8/10 Excellent! (1,171 reviews)
"Rooms can use an update. Restaurants and staff very good."

Reviewed on Jan 8, 2025

Hotel Encanto de Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces
3 out of 5
201 E University Avenue, I-10 Exit 142, Las Cruces, NM
  • 27 min walk from Mesillia Plaza
The price is $81 per night from Jan 19 to Jan 20
$81
includes taxes & fees
Jan 19 - Jan 20
Stay at this 3-star spa hotel in Las Cruces. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,003 reviews)
"Beautiful Interior!"

Reviewed on Jan 8, 2025

Ramada Hotel & Conference Center by Wyndham Las Cruces
Comfort Suites Las Cruces I-25 North
Comfort Suites Las Cruces I-25 North
2.5 out of 5
236 N Telshor Blvd., Las Cruces, NM
  • 9 min drive from Mesillia Plaza
The price is $114 per night from Jan 24 to Jan 25
$114
includes taxes & fees
Jan 24 - Jan 25
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
Nice comfortable and spacious accommodation
"Staff was friendly and helpful. Breakfast had a good selection and area was neat and comfortable. We were traveling with our dog and the facility had outdoor area and cleanup items available for use."

Reviewed on Jan 7, 2025

Comfort Suites Las Cruces I-25 North
Days Inn by Wyndham Las Cruces
Days Inn by Wyndham Las Cruces
2.5 out of 5
755 Avenida De Mesilla, Las Cruces, NM
  • 25 min walk from Mesillia Plaza
The price is $59 per night from Jan 21 to Jan 22
$59
includes taxes & fees
Jan 21 - Jan 22
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,148 reviews)
"good"

Reviewed on Jan 7, 2025

Days Inn by Wyndham Las Cruces
Comfort Suites University Las Cruces
Comfort Suites University Las Cruces
2.5 out of 5
2101 S Triviz Drive, Las Cruces, NM
  • 6 min drive from Mesillia Plaza
The price is $87 per night from Jan 19 to Jan 20
$87
includes taxes & fees
Jan 19 - Jan 20
Book a stay at this golf hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (1,002 reviews)
"Clean and comfortable"

Reviewed on Jan 8, 2025

Comfort Suites University Las Cruces
Hilton Garden Inn Las Cruces
Hilton Garden Inn Las Cruces
3 out of 5
2550 Don Roser Dr, Las Cruces, NM
  • 7 min drive from Mesillia Plaza
The price is $107 per night from Jan 26 to Jan 27
$107
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,003 reviews)
"Comfy and quiet"

Reviewed on Jan 9, 2025

Hilton Garden Inn Las Cruces
Best Western Mission Inn
Best Western Mission Inn
2.5 out of 5
1765 S Main St, Las Cruces, NM
  • 28 min walk from Mesillia Plaza
The price is $94 per night from Jan 12 to Jan 13
$94
includes taxes & fees
Jan 12 - Jan 13
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,090 reviews)
"2nd floor has no elevators or handicap access. First floor okay for same... 2nd floor is fine except for senior citizens with or without handicapped status..."

Reviewed on Jan 8, 2025

Best Western Mission Inn
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
2.5 out of 5
790 Avenida De Mesilla, Las Cruces, NM
  • 26 min walk from Mesillia Plaza
The price is $69 per night from Jan 13 to Jan 14
$69
includes taxes & fees
Jan 13 - Jan 14
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the clean rooms in our reviews. ...
5.8/10 (1,004 reviews)
"."

Reviewed on Jan 8, 2025

La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Drury Inn & Suites Las Cruces
Drury Inn & Suites Las Cruces
3 out of 5
1631 Hickory Loop, Las Cruces, NM
  • 24 min walk from Mesillia Plaza
The price is $125 per night from Jan 20 to Jan 21
$125
includes taxes & fees
Jan 20 - Jan 21
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
"Very comfortable and convenient"

Reviewed on Jan 6, 2025

Drury Inn & Suites Las Cruces
Hampton Inn & Suites Las Cruces I-10
Hampton Inn & Suites Las Cruces I-10
2.5 out of 5
1641 Hickory Loop, Las Cruces, NM
  • 24 min walk from Mesillia Plaza
The price is $117 per night from Feb 5 to Feb 6
$117
includes taxes & fees
Feb 5 - Feb 6
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"Excellent expirence very quiet and comfortable"

Reviewed on Jan 4, 2025

Hampton Inn & Suites Las Cruces I-10
Staybridge Suites Las Cruces, an IHG Hotel
Staybridge Suites Las Cruces, an IHG Hotel
3 out of 5
2651 Northrise Dr, Las Cruces, NM
  • 13 min drive from Mesillia Plaza
The price is $133 per night from Jan 27 to Jan 28
$133
includes taxes & fees
Jan 27 - Jan 28
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,000 reviews)
Great place to stay but....
"This is our second time staying at this location. The hotel itself is great. The breakfast needs serious help. Breakfast is NOT ready at start time. They run out of plates in the first 20 mins. Some food is cold. Coffee is not ready. Drink machines not turned on, etc. Stayed 2 months apart with same ..."

Reviewed on Jan 6, 2025

Staybridge Suites Las Cruces, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mesilla

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Mesilla hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mesilla.

Choosing the right hotel in New Mexico has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mesilla’s 343 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Mesilla hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mesilla. No matter your reason for visiting Mesilla, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Mesilla hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mesilla for as low as $59.

How many hotels are there in Mesilla?

With over 343 hotels in Mesilla, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.

How to find cheap car rentals in Mesilla?

Finding a cheap car rental deal in Mesilla is as easy as scoring cheap hotels in Mesilla. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.