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Hotels in Mesilla

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Choose from 377 Mesilla Hotel Deals

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

3.5 out of 5
705 S Telshor Blvd Las Cruces NM
  • 9 min drive from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy 3 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,606 reviews)
We stayed in an updated room that was quiet on a corner end.

Reviewed on Dec 27, 2025

Hotel Encanto de Las Cruces
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

3 out of 5
1500 Hickory Dr Las Cruces NM
  • 23 min walk from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (2,301 reviews)
Inexpensive, clean rooms and a courteous staff, could not ask for more. Thank you.

Reviewed on Dec 29, 2025

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

2.5 out of 5
755 Avenida De Mesilla Las Cruces NM
  • 25 min walk from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,299 reviews)
Room was great and pretty clean. I wished I could have used the pool, but they said its closed in winter. O well. Other than that, good place to be and breakfast waa great too. Easy in and out.

Reviewed on Dec 25, 2025

Days Inn by Wyndham Las Cruces
Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces

3 out of 5
2550 Don Roser Dr Las Cruces NM
  • 7 min drive from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,007 reviews)
Clean room, comfortable bed, great water pressure in shower.

Reviewed on Dec 29, 2025

Hilton Garden Inn Las Cruces
Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

3 out of 5
1631 Hickory Loop Las Cruces NM
  • 24 min walk from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
Staff was great!

Reviewed on Dec 25, 2025

Drury Inn & Suites Las Cruces
Comfort Suites University Las Cruces

Comfort Suites University Las Cruces

2.5 out of 5
2101 S Triviz Drive Las Cruces NM
  • 6 min drive from Mesillia Plaza
Book a stay at this golf hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (1,001 reviews)
Good places

Reviewed on Dec 27, 2025

Comfort Suites University Las Cruces
Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North

2.5 out of 5
236 N Telshor Blvd. Las Cruces NM
  • 9 min drive from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
Clean room, friendly staff and good location

Reviewed on Dec 28, 2025

Comfort Suites Las Cruces I-25 North
Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25

2.5 out of 5
2350 E Griggs Ave Las Cruces NM
  • 9 min drive from Mesillia Plaza
Stay at this hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (1,002 reviews)
good

Reviewed on Dec 25, 2025

Hampton Inn & Suites Las Cruces I-25
Best Western Mission Inn

Best Western Mission Inn

2.5 out of 5
1765 S Main St Las Cruces NM
  • 28 min walk from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,232 reviews)
Old fashioned but perfectly comfortable for one night on the road and fairly priced. Would not hesitate to stay there again.

Reviewed on Dec 21, 2025

Best Western Mission Inn
Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG

3 out of 5
2651 Northrise Dr Las Cruces NM
  • 13 min drive from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,004 reviews)
clean,and people are really nice

Reviewed on Dec 26, 2025

Staybridge Suites Las Cruces by IHG
Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10

2.5 out of 5
1641 Hickory Loop Las Cruces NM
  • 24 min walk from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
Clean, great staff, comfortable rooms.

Reviewed on Dec 21, 2025

Hampton Inn & Suites Las Cruces I-10
Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG

2.5 out of 5
2142 Telshor Ct Las Cruces NM
  • 12 min drive from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (980 reviews)
Breakfast was great.

Reviewed on Dec 22, 2025

Holiday Inn Express & Suites Las Cruces North by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mesilla

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How many hotels are there in Mesilla?

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