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Choose from 332 Mesilla Hotel Deals

Hotel Encanto de Las Cruces
Reviewed on Jul 14, 2025

Ramada Hotel & Conference Center by Wyndham Las Cruces
Reviewed on Jul 8, 2025

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Reviewed on Jul 14, 2025

Days Inn by Wyndham Las Cruces
Reviewed on Jul 15, 2025

Best Western Mission Inn
Reviewed on Jul 14, 2025

Comfort Suites Las Cruces I-25 North
Reviewed on Jul 14, 2025

Drury Inn & Suites Las Cruces
Reviewed on Jul 14, 2025

La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Reviewed on Jul 1, 2025

Comfort Suites University Las Cruces
Reviewed on Jun 15, 2025

Springhill Suites By Marriott Las Cruces
Reviewed on Jul 5, 2025

Hilton Garden Inn Las Cruces
Reviewed on Jul 16, 2025

Comfort Inn & Suites Las Cruces Mesilla
Reviewed on Jul 15, 2025
Find cheap hotels in Mesilla
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mesilla.
Choosing the right hotel in New Mexico has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mesilla’s 332 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $60. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Mesilla hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mesilla. No matter your reason for visiting Mesilla, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Mesilla hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mesilla for as low as $60.
How many hotels are there in Mesilla?
With over 332 hotels in Mesilla, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $60.
How to find cheap car rentals in Mesilla?
Finding a cheap car rental deal in Mesilla is as easy as scoring cheap hotels in Mesilla. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
Top Booked Hotels in Mesilla
- Hotel Encanto de Las Cruces
- Ramada Hotel & Conference Center by Wyndham Las Cruces
- La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
- Days Inn by Wyndham Las Cruces
- Best Western Mission Inn
- Comfort Suites Las Cruces I-25 North
- La Quinta Inn by Wyndham Las Cruces Mesilla Valley
- Comfort Suites University Las Cruces
- Springhill Suites By Marriott Las Cruces
- Hilton Garden Inn Las Cruces
- Comfort Inn & Suites Las Cruces Mesilla
- Quality Inn & Suites Las Cruces - University Area
- Hampton Inn & Suites Las Cruces I-25
- Hampton Inn & Suites Las Cruces I-10
- Super 8 by Wyndham Las Cruces/White Sands Area
- Hotels near Mesillia Plaza
- Hotels near Fountain Theatre
- Hotels near Fountain Theater
- Hotels near San Albino Basilica
- Hotels near New Mexico State University
- Hotels near Rio Grande
- Hotels near Mesilla Valley Mall
- Hotels near Sonoma Ranch Golf Course
- Hotels near New Mexico Farm and Ranch Heritage Museum
- Hotels near Red Hawk Golf Club
- Hotels near Dripping Springs Natural Area
- Hotels near Las Cruces Museum of Art
- Hotels near Rio Grande Vineyards and Winery
- Hotels near Las Cruces Community Theatre
- Hotels near Las Cruces Museum of Fine Arts and Culture
- Hotels near Dos Lagos Golf Course