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Hotels in Mesilla

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Check Last Minute Mesilla Hotel Deals

Tonight Nov 23 - Nov 24Next weekend Nov 29 - Dec 1

Choose from 346 Mesilla Hotel Deals

Ramada Hotel & Conference Center by Wyndham Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces
3 out of 5
201 E University Avenue, I-10 Exit 142, Las Cruces, NM
  • 27 min walk from Mesillia Plaza
The price is $83 per night from Nov 25 to Nov 26
$83
includes taxes & fees
Nov 25 - Nov 26
Book a stay at this spa hotel in Las Cruces. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,004 reviews)
Southwestern Charm
"Older hotel, but very charming. Room right off interior courtyard. Lots of southwestern charm."

Reviewed on Nov 21, 2024

Ramada Hotel & Conference Center by Wyndham Las Cruces
Hotel Encanto de Las Cruces
Hotel Encanto de Las Cruces
3.5 out of 5
705 S Telshor Blvd, Las Cruces, NM
  • 9 min drive from Mesillia Plaza
The price is $152 per night from Dec 9 to Dec 10
$152
includes taxes & fees
Dec 9 - Dec 10
Book a stay at this business-friendly hotel in Las Cruces. Enjoy 3 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the pool and the helpful ...
8.8/10 Excellent! (1,130 reviews)
"Hotel Encanto was very nice, clean snd the staff was great the whole weekend everyone was polite and attentive! I would and will stay here again."

Reviewed on Nov 15, 2024

Hotel Encanto de Las Cruces
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
2.5 out of 5
1500 Hickory Dr, Las Cruces, NM
  • 23 min walk from Mesillia Plaza
The price is $73 per night from Dec 1 to Dec 2
$73
includes taxes & fees
Dec 1 - Dec 2
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,905 reviews)
"Receptionist was really friendly"

Reviewed on Nov 20, 2024

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Days Inn by Wyndham Las Cruces
Days Inn by Wyndham Las Cruces
2.5 out of 5
755 Avenida De Mesilla, Las Cruces, NM
  • 25 min walk from Mesillia Plaza
The price is $59 per night from Nov 26 to Nov 27
$59
includes taxes & fees
Nov 26 - Nov 27
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,170 reviews)
"Great value. Older property that has a new coat of paint to freshen it up. Continental breakfast was more than adequate. Loved being able to park outside my door for convenience of loading and unloading into our room. No complaints. We will come back."

Reviewed on Nov 20, 2024

Days Inn by Wyndham Las Cruces
Comfort Suites Las Cruces I-25 North
Comfort Suites Las Cruces I-25 North
2.5 out of 5
236 N Telshor Blvd., Las Cruces, NM
  • 9 min drive from Mesillia Plaza
The price is $136 per night from Dec 8 to Dec 9
$136
includes taxes & fees
Dec 8 - Dec 9
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
"Great location"

Reviewed on Nov 18, 2024

Comfort Suites Las Cruces I-25 North
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
2.5 out of 5
790 Avenida De Mesilla, Las Cruces, NM
  • 26 min walk from Mesillia Plaza
The price is $57 per night from Nov 26 to Nov 27
$57
includes taxes & fees
Nov 26 - Nov 27
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the clean rooms in our reviews. ...
5.8/10 (1,002 reviews)
Great stay
"I like coming here it's a lot more better with the new owner ship than the last owners"

Reviewed on Nov 13, 2024

La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Best Western Mission Inn
Best Western Mission Inn
2.5 out of 5
1765 S Main St, Las Cruces, NM
  • 28 min walk from Mesillia Plaza
The price is $94 per night from Dec 4 to Dec 5
$94
includes taxes & fees
Dec 4 - Dec 5
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,086 reviews)
"Excellent, pretty and clean, great service!"

Reviewed on Nov 22, 2024

Best Western Mission Inn
Drury Inn & Suites Las Cruces
Drury Inn & Suites Las Cruces
3 out of 5
1631 Hickory Loop, Las Cruces, NM
  • 24 min walk from Mesillia Plaza
The price is $125 per night from Dec 1 to Dec 2
$125
includes taxes & fees
Dec 1 - Dec 2
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
"Hotel was nice."

Reviewed on Nov 19, 2024

Drury Inn & Suites Las Cruces
Home2 Suites by Hilton Las Cruces
Home2 Suites by Hilton Las Cruces
3 out of 5
1120 North Telshor Boulevard, Las Cruces, NM
  • 11 min drive from Mesillia Plaza
The price is $156 per night from Nov 26 to Nov 27
$156
includes taxes & fees
Nov 26 - Nov 27
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (547 reviews)
Renovated, always a great stay.
"Back after three years, the hotel is going through a renovation. I got the suite for the first time and it was great. You pick up some noise from the freeway, breakfast is acceptable. Front desk crews very friendly and useful."

Reviewed on Nov 21, 2024

Home2 Suites by Hilton Las Cruces
Hampton Inn & Suites Las Cruces I-10
Hampton Inn & Suites Las Cruces I-10
2.5 out of 5
1641 Hickory Loop, Las Cruces, NM
  • 24 min walk from Mesillia Plaza
The price is $122 per night from Dec 22 to Dec 23
$122
includes taxes & fees
Dec 22 - Dec 23
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
Phoenix Trip
"Very nice friendly personale. Clean rooms."

Reviewed on Nov 9, 2024

Hampton Inn & Suites Las Cruces I-10
Staybridge Suites Las Cruces, an IHG Hotel
Staybridge Suites Las Cruces, an IHG Hotel
3 out of 5
2651 Northrise Dr, Las Cruces, NM
  • 13 min drive from Mesillia Plaza
The price is $133 per night from Dec 8 to Dec 9
$133
includes taxes & fees
Dec 8 - Dec 9
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,001 reviews)
"Wonderful experience and great staff"

Reviewed on Nov 18, 2024

Staybridge Suites Las Cruces, an IHG Hotel
Comfort Suites University Las Cruces
Comfort Suites University Las Cruces
2.5 out of 5
2101 S Triviz Drive, Las Cruces, NM
  • 6 min drive from Mesillia Plaza
The price is $97 per night from Dec 8 to Dec 9
$97
includes taxes & fees
Dec 8 - Dec 9
Book a stay at this golf hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (1,000 reviews)
"Room was clean and really nice and spacious. Breakfast was good. It was a complete breakfast - not just muffins and juice. Quite a variety of things. Would definitely stay there again."

Reviewed on Nov 15, 2024

Comfort Suites University Las Cruces
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mesilla

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Mesilla hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mesilla.

Choosing the right hotel in New Mexico has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mesilla’s 346 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $57. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Mesilla hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mesilla. No matter your reason for visiting Mesilla, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Mesilla hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mesilla for as low as $57.

How many hotels are there in Mesilla?

With over 346 hotels in Mesilla, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $57.

How to find cheap car rentals in Mesilla?

Finding a cheap car rental deal in Mesilla is as easy as scoring cheap hotels in Mesilla. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Mesilla now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Mesilla right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.