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Hotels in Mesilla

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Choose from 328 Mesilla Hotel Deals

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

3.5 out of 5
705 S Telshor Blvd, Las Cruces, NM
  • 9 min drive from Mesillia Plaza
Stay at this 3.5-star business-friendly hotel in Las Cruces. Enjoy 3 bars/lounges, a nightclub, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (1,391 reviews)
"Great environment! Loves the staff and room."

Reviewed on Jul 20, 2025

Hotel Encanto de Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces

3 out of 5
201 E University Avenue, I-10 Exit 142, Las Cruces, NM
  • 27 min walk from Mesillia Plaza
Stay at this 3-star spa hotel in Las Cruces. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,007 reviews)
"It was very pleasant. Didn't use the room much since at a conference. It was very good service with a helpful and polite staff."

Reviewed on Jul 20, 2025

Ramada Hotel & Conference Center by Wyndham Las Cruces
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

3 out of 5
1500 Hickory Dr, Las Cruces, NM
  • 23 min walk from Mesillia Plaza
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (2,180 reviews)
"Staff was very nice"

Reviewed on Jul 23, 2025

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

2.5 out of 5
755 Avenida De Mesilla, Las Cruces, NM
  • 25 min walk from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,187 reviews)
"Everything was great!"

Reviewed on Jul 18, 2025

Days Inn by Wyndham Las Cruces
Best Western Mission Inn

Best Western Mission Inn

2.5 out of 5
1765 S Main St, Las Cruces, NM
  • 28 min walk from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,191 reviews)
Slept Well
"The hotel is quaint & the rooms are spacious. It was quiet & comfortable. I slept well."

Reviewed on Jul 20, 2025

Best Western Mission Inn
Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North

2.5 out of 5
236 N Telshor Blvd., Las Cruces, NM
  • 9 min drive from Mesillia Plaza
Book a stay at this business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Very clean rooms, good amenities and i love that they are pet friendly."

Reviewed on Jul 22, 2025

Comfort Suites Las Cruces I-25 North
Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25

2.5 out of 5
2350 E Griggs Ave, Las Cruces, NM
  • 9 min drive from Mesillia Plaza
Stay at this hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (1,007 reviews)
"The property was under renovation and we did not know that Expedia doesn't let you know.. we only had 6 stations on the tv and they were doing construction in dinning area and upstairs. The staff was great very sweet and friendly"

Reviewed on Jul 20, 2025

Hampton Inn & Suites Las Cruces I-25
Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

3 out of 5
1631 Hickory Loop, Las Cruces, NM
  • 24 min walk from Mesillia Plaza
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
Great place to stay.
"We always pick this place to stay. Great place, clean and spacious rooms and nice staff! Decent breakfast and evening snack options."

Reviewed on Jul 20, 2025

Drury Inn & Suites Las Cruces
La Quinta Inn by Wyndham Las Cruces Mesilla Valley

La Quinta Inn by Wyndham Las Cruces Mesilla Valley

3 out of 5
790 Avenida De Mesilla, Las Cruces, NM
  • 26 min walk from Mesillia Plaza
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the clean rooms in our reviews. ...
5.6/10 (1,005 reviews)
"There was plenty of parking, the area was clean and convenient to fast food."

Reviewed on Jul 1, 2025

La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces

3 out of 5
1611 Hickory Loop, Las Cruces, NM
  • 26 min walk from Mesillia Plaza
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (890 reviews)
"I really like the service"

Reviewed on Jul 21, 2025

Springhill Suites By Marriott Las Cruces
Comfort Suites University Las Cruces

Comfort Suites University Las Cruces

2.5 out of 5
2101 S Triviz Drive, Las Cruces, NM
  • 6 min drive from Mesillia Plaza
Book a stay at this golf hotel in Las Cruces. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (1,005 reviews)
"Clean"

Reviewed on Jul 21, 2025

Comfort Suites University Las Cruces
Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces

3 out of 5
2550 Don Roser Dr, Las Cruces, NM
  • 7 min drive from Mesillia Plaza
Stay at this 3-star business-friendly hotel in Las Cruces. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,004 reviews)
"Had my dad’s celebration of life here, room were clean, staff super friendly! Event room was perfect, lots of friends & family also stayed here! Great for large groups…"

Reviewed on Jul 17, 2025

Hilton Garden Inn Las Cruces
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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