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Featured Eastern South Dakota Resorts & Hotels with Spas
Hampton Inn Sioux Falls
2417 S Carolyn Ave, Sioux Falls, SD
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
La Quinta Inn & Suites by Wyndham Sioux Falls
4521 W. 41st Street, Sioux Falls, SD
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Holiday Inn Sioux Falls-City Centre, an IHG Hotel
100 W 8th St, Sioux Falls, SD
Fully refundable
Stay at this 3-star business-friendly hotel in Sioux Falls. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
Holiday Inn Express & Suites Sioux Falls At Empire Mall, an IHG Hotel
2501 S Shirley Ave, Sioux Falls, SD
Fully refundable
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Fairfield Inn & Suites Sioux Falls Airport
4035 Bobhalla Drive, Sioux Falls, SD
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Quality Inn & Suites South
3216 S Carolyn Ave, Sioux Falls, SD
Stay at this hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Staybridge Suites Sioux Falls, an IHG Hotel
2505 S Carolyn Ave, Sioux Falls, SD
Fully refundable
Stay at this 3-star business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Ramada by Wyndham Sioux Falls
407 South Lyons Avenue, Sioux Falls, SD
Fully refundableReserve now, pay when you stay
Stay at this hotel in Sioux Falls. Enjoy free breakfast, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
AmericInn by Wyndham Aberdeen - Event Center
301 Centennial St, Aberdeen, SD
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Aberdeen. Enjoy free breakfast, free parking, and a casino. Our guests praise the breakfast and the helpful staff ...
AmericInn by Wyndham Mitchell
1421 South Burr Street, Mitchell, SD
Fully refundableReserve now, pay when you stay
Stay at this hotel in Mitchell. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Best Western Kelly Inn
1607 E Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Yankton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Best Western Of Huron
2000 Dakota Ave S, Huron, SD
Fully refundableReserve now, pay when you stay
Stay at this hotel in Huron. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Prospect ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Eastern South Dakota
- Hotels with Free Parking in Eastern South Dakota
- Family Hotels in Eastern South Dakota
- Pet-friendly Hotels in Eastern South Dakota
- Hotels with a Pool in Eastern South Dakota
- Hotels with an Indoor Pool in Eastern South Dakota
- Hotels with Hot Tubs in Eastern South Dakota
- Historic Hotels in Eastern South Dakota
- Luxury Hotels in Eastern South Dakota
- Hotel Wedding Venues in Eastern South Dakota
- Hotels with Free Airport Shuttle in Eastern South Dakota
Top Points of Interests in Eastern South Dakota
- Hotels near Denny Sanford Premier Center
- Hotels near Sanford USD Medical Center
- Hotels near Empire Mall
- Hotels near Falls Park
- Hotels near Sanford Pentagon
- Hotels near Sioux Empire Fairgrounds
- Hotels near Sioux Falls Convention Center
- Hotels near Grand Falls Casino Resort
- Hotels near South Dakota State University
- Hotels near Washington Pavilion of Arts and Science
- Hotels near Augustana College
- Hotels near Great Bear Recreation Park
- Hotels near Sioux Falls Arena
- Hotels near University of South Dakota
- Hotels near Watertown Mall
- Hotels near Great Plains Zoo
- Hotels near Big Stone Lake
- Hotels near Corn Palace
- Hotels near University of Sioux Falls
- Hotels near Pipestone National Monument
Cities near Eastern South Dakota
- Sioux Falls Hotels (66.45 mi)
- Sioux City Hotels (137.67 mi)
- Brookings Hotels (37.27 mi)
- Mitchell Hotels (47.07 mi)
- Aberdeen Hotels (92.28 mi)
- Watertown Hotels (46.44 mi)
- Yankton Hotels (99.2 mi)
- Chamberlain Hotels (94.54 mi)
- Central Minnesota Hotels (167.72 mi)
- Huron Hotels (32.93 mi)
- Webster Hotels (71.05 mi)
- Worthington Hotels (108.02 mi)
- Brandon Hotels (69.08 mi)
- Vermillion Hotels (109.91 mi)
- Larchwood Hotels (80.89 mi)
- Sioux Center Hotels (109.15 mi)
- North Sioux City Hotels (133.87 mi)
- Southern Minnesota Hotels (176.06 mi)
- Ortonville Hotels (87.9 mi)
- Waubay Hotels (72.05 mi)
Car Rentals Near Eastern South Dakota
- Car rentals in Sioux Falls
- Car rentals in Sioux City
- Car rentals in Brookings
- Car rentals in Mitchell
- Car rentals in Aberdeen
- Car rentals in Watertown
- Car rentals in Yankton
- Car rentals in Chamberlain
- Car rentals in Central Minnesota
- Car rentals in Huron
- Car rentals in Webster
- Car rentals in Worthington
- Car rentals in Brandon
- Car rentals in Vermillion
- Car rentals in Larchwood
- Car rentals in Sioux Center
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Eastern South Dakota
- Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
- La Quinta Inn & Suites by Wyndham Sioux Falls
- Days Inn by Wyndham Sioux Falls Empire
- Baymont by Wyndham Sioux Falls
- Hotel On Phillips
- AmericInn by Wyndham Sioux Falls
- Country Inn & Suites by Radisson, Sioux Falls, SD
- AmericInn by Wyndham Sioux Falls North
- Clubhouse Hotel Suites Sioux Falls
- Holiday Inn Sioux Falls-City Centre, an IHG Hotel
- AeroStay Hotel