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Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
  • 12 min drive from Clark Memorial Hospital
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.4/10 Exceptional! (441 reviews)
Very clean and comfortable room. The staff was great!

Reviewed on Feb 7, 2026

Hilton Garden Inn Jeffersonville Louisville North
Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott

3.5 out of 5
700 West Riverside Drive Jeffersonville IN
  • 19 min walk from Clark Memorial Hospital
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free WiFi, free parking, and 3 bars/lounges. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,000 reviews)
Friendly helpful staff, clean rooms, well equipped gym. Easy parking & walkable to restaurants & town. Louisville just over the bridge.

Reviewed on Jan 27, 2026

Sheraton Louisville Riverside by Marriott
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
  • 4 min drive from Clark Memorial Hospital
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
8.8/10 Excellent! (4,061 reviews)
Great stay and excellent, large rooms

Reviewed on Feb 11, 2026

Galt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
  • 5 min drive from Clark Memorial Hospital
Book a stay at this spa hotel in Louisville. Enjoy a full-service spa, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,769 reviews)
All good

Reviewed on Feb 5, 2026

Omni Louisville Hotel
Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
  • 8 min walk from Clark Memorial Hospital
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
6.8/10 (2,784 reviews)
Decent not super clean but better than a lot of places

Reviewed on Feb 7, 2026

Radisson Hotel Louisville North
Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

3.5 out of 5
830 Phillips Lane Louisville KY
  • 15 min drive from Clark Memorial Hospital
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the ...
8.8/10 Excellent! (1,155 reviews)
Todo estuvo perfecto estamos muy contentos

Reviewed on Feb 9, 2026

Crowne Plaza Louisville Airport Expo Ctr by IHG
Derby City Gaming & Hotel -  A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4 out of 5
4520 Poplar Level Rd Louisville KY
  • 17 min drive from Clark Memorial Hospital
Stay at this hotel in Louisville. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
9.4/10 Exceptional! (1,814 reviews)
Very clean room

Reviewed on Feb 12, 2026

Derby City Gaming & Hotel - A Churchill Downs Property
Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown

3.5 out of 5
350 West Chestnut Street Louisville KY
  • 6 min drive from Clark Memorial Hospital
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.4/10 Very Good! (1,007 reviews)
The lady at check in was so nice. Our room was amazing.

Reviewed on Feb 6, 2026

Hilton Garden Inn Louisville Downtown
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4 out of 5
501 South Fourth Street Louisville KY
  • 5 min drive from Clark Memorial Hospital
Stay at this hotel in Louisville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in ...
8.8/10 Excellent! (1,158 reviews)
Great room and location!!! Friendly staff and transparent pricing. Would definitely stay again!!

Reviewed on Feb 13, 2026

Embassy Suites Louisville Downtown
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
  • 5 min drive from Clark Memorial Hospital
Book a stay at this luxury hotel in Louisville. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
Great atmosphere, love the art that surrounds you at every turn

Reviewed on Feb 6, 2026

21c Museum Hotel Louisville
The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
  • 6 min drive from Clark Memorial Hospital
Book a stay at this luxury hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,184 reviews)
Quiet room, great coffee, engaged, informative, friendly staff. Brunch buffet a joy

Reviewed on Feb 8, 2026

The Brown Hotel
Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo

2.5 out of 5
3200 Kemmons Drive Louisville KY
  • 16 min drive from Clark Memorial Hospital
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,237 reviews)
Yes

Reviewed on Jan 31, 2026

Wingate by Wyndham Louisville Fair and Expo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Jeffersonville

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Jeffersonville.

Choosing the right hotel in Indiana has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Jeffersonville’s 2,152 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $67. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Jeffersonville hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Jeffersonville. No matter your reason for visiting Jeffersonville, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Jeffersonville hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Jeffersonville?

With over 2,152 hotels in Jeffersonville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $67.

How to find cheap car rentals in Jeffersonville?

Finding a cheap car rental deal in Jeffersonville is as easy as scoring cheap hotels in Jeffersonville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.