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Hotels in Southern Indiana

Choose from 1600 Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
  • 5 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
6.8/10 (2,686 reviews)
Good

Reviewed on Dec 31, 2025

Radisson Hotel Louisville North
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
  • 16 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.4/10 Exceptional! (422 reviews)
nice hotel, nice staff and bar.

Reviewed on Dec 23, 2025

Hilton Garden Inn Jeffersonville Louisville North
Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North

2.5 out of 5
1485 Broadway St Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,001 reviews)
Room is beautiful! Excellent condition and clean! Staff is very friendly and accommodating! I recommend this Comfort Inn if you are looking in this area.

Reviewed on Dec 20, 2025

Comfort Inn & Suites Clarksville - Louisville North
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (745 reviews)
Didn't eat breakfast

Reviewed on Dec 30, 2025

Hampton Inn New Albany Louisville West
Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

3 out of 5
100 Cross Pointe Blvd Evansville IN
  • 4 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,006 reviews)
Clean room, friendly staff including the bartenders; very friendly and hospitable. Hot tub very clean, nice and refreshing. Comfy and cozy room and beds. Pool cool and refreshing. Stayed for Christmas; was hoping to have something a little different at hotel or special on buffet because of the holiday. ...

Reviewed on Dec 28, 2025

Drury Inn & Suites Evansville East
Bally’s Evansville Casino & Hotel

Bally’s Evansville Casino & Hotel

3 out of 5
421 NW Riverside Drive Evansville IN
  • 5 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,267 reviews)
Clean updated room

Reviewed on Dec 26, 2025

Bally’s Evansville Casino & Hotel
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

3 out of 5
301 West Maple Street Jeffersonville IN
  • 23 min walk from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (645 reviews)
Clean room, staff at check in and breakfast

Reviewed on Dec 23, 2025

TownePlace Suites by Marriott Louisville North
Hyatt Place Evansville

Hyatt Place Evansville

3 out of 5
202 Se 2nd St Evansville IN
  • 5 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,004 reviews)
Room was very clean

Reviewed on Dec 28, 2025

Hyatt Place Evansville
Home2 Suites by Hilton Clarksville Louisville North

Home2 Suites by Hilton Clarksville Louisville North

3 out of 5
1624 Leisure Way Clarksville IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (426 reviews)
Clea

Reviewed on Dec 15, 2025

Home2 Suites by Hilton Clarksville Louisville North
Best Western Green Tree Inn

Best Western Green Tree Inn

2.5 out of 5
1425 Broadway Street Clarksville IN
  • 11 min drive from KFC Yum Center
Stay at this hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,000 reviews)
I enjoyed my stay a lot! Convenient location with lots of restaurant options near by. The breakfast options were wonderful, and delicious! Room was clean, bed was comfortable, and being able to park in front of my room door was so convenient. I will stay there again.

Reviewed on Dec 26, 2025

Best Western Green Tree Inn
Hampton Inn Evansville

Hampton Inn Evansville

3 out of 5
8000 Eagle Crest Boulevard Evansville IN
  • 4 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,002 reviews)
Room was very nice and clean

Reviewed on Dec 26, 2025

Hampton Inn Evansville
Hampton Inn Louisville-North/Clarksville

Hampton Inn Louisville-North/Clarksville

2.5 out of 5
1501 Broadway Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (670 reviews)
Quiet location. Comfortable bed. Hot breakfast! Loved the strawberries, almonds, & whip cream for the waffles.

Reviewed on Dec 20, 2025

Hampton Inn Louisville-North/Clarksville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southern Indiana

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Indiana.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Indiana’s 1,600 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $66. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southern Indiana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Indiana. No matter your reason for visiting Southern Indiana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southern Indiana hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Southern Indiana?

With over 1,600 hotels in Southern Indiana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $66.

How to find cheap car rentals in Southern Indiana?

Finding a cheap car rental deal in Southern Indiana is as easy as scoring cheap hotels in Southern Indiana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.