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Hotels in Southern Indiana

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Choose from 1637 Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
  • 5 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
6.8/10 (2,725 reviews)
Great view

Reviewed on Jan 11, 2026

Radisson Hotel Louisville North
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (751 reviews)
Didn’t get to get breakfast I slept straight through it. Rooms very clean staff was great

Reviewed on Jan 1, 2026

Hampton Inn New Albany Louisville West
Bally’s Evansville Casino & Hotel

Bally’s Evansville Casino & Hotel

3 out of 5
421 NW Riverside Drive Evansville IN
  • 5 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,266 reviews)
Great staff

Reviewed on Jan 7, 2026

Bally’s Evansville Casino & Hotel
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

3 out of 5
301 West Maple Street Jeffersonville IN
  • 23 min walk from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (653 reviews)
Very clean, great location, good breakfast, enjoyed the pool and hot tub. Would definitely stay again

Reviewed on Jan 11, 2026

TownePlace Suites by Marriott Louisville North
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
  • 16 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.4/10 Exceptional! (431 reviews)
Room was great. Clean and comfortable.

Reviewed on Jan 8, 2026

Hilton Garden Inn Jeffersonville Louisville North
Hyatt Place Evansville

Hyatt Place Evansville

3 out of 5
202 Se 2nd St Evansville IN
  • 5 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
Loved it here.

Reviewed on Jan 14, 2026

Hyatt Place Evansville
Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

3 out of 5
100 Cross Pointe Blvd Evansville IN
  • 4 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
Great stay!

Reviewed on Jan 15, 2026

Drury Inn & Suites Evansville East
Hampton Inn Evansville

Hampton Inn Evansville

3 out of 5
8000 Eagle Crest Boulevard Evansville IN
  • 4 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,000 reviews)
A

Reviewed on Jan 11, 2026

Hampton Inn Evansville
Big Splash Adventure Indoor Water Park & Resort

Big Splash Adventure Indoor Water Park & Resort

3.5 out of 5
8505 W State Road 56 French Lick IN
  • 2 hours drive from KFC Yum Center
Book a stay at this family-friendly resort in French Lick. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions French Lick Scenic Railway and ...
7.6/10 Good! (187 reviews)
Yes

Reviewed on Dec 15, 2025

Big Splash Adventure Indoor Water Park & Resort
Hampton Inn Louisville-North/Clarksville

Hampton Inn Louisville-North/Clarksville

2.5 out of 5
1501 Broadway Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (670 reviews)
Quiet location. Comfortable bed. Hot breakfast! Loved the strawberries, almonds, & whip cream for the waffles.

Reviewed on Dec 20, 2025

Hampton Inn Louisville-North/Clarksville
La Quinta Inn & Suites by Wyndham Evansville

La Quinta Inn & Suites by Wyndham Evansville

3 out of 5
8015 East Division Street Evansville IN
  • 4 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
Worth every dollar. The staff and room were exceptional. Will book again.

Reviewed on Jan 11, 2026

La Quinta Inn & Suites by Wyndham Evansville
DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

4 out of 5
601 Walnut Street Evansville IN
  • 5 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.6/10 Excellent! (1,002 reviews)
Didnt eat breakfast.

Reviewed on Dec 22, 2025

DoubleTree by Hilton Evansville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southern Indiana

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Indiana.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Indiana’s 1,637 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $63. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southern Indiana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Indiana. No matter your reason for visiting Southern Indiana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southern Indiana hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southern Indiana for as low as $63.

How many hotels are there in Southern Indiana?

With over 1,637 hotels in Southern Indiana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $63.

How to find cheap car rentals in Southern Indiana?

Finding a cheap car rental deal in Southern Indiana is as easy as scoring cheap hotels in Southern Indiana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.