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Choose from 1635 Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
  • 5 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (2,806 reviews)
Somewhat better

Reviewed on Mar 1, 2026

Radisson Hotel Louisville North
Bally’s Evansville Casino & Hotel

Bally’s Evansville Casino & Hotel

3 out of 5
421 NW Riverside Drive Evansville IN
  • 5 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,273 reviews)
Only complaint is that housekeeping knocked on the door at 8:30 to clean

Reviewed on Feb 28, 2026

Bally’s Evansville Casino & Hotel
Fairfield Inn By Marriott Evansville East

Fairfield Inn By Marriott Evansville East

2.5 out of 5
7879 Eagle Crest Blvd Evansville IN
  • 4 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (469 reviews)
Clean property, clean rooms, great free breakfast!

Reviewed on Feb 22, 2026

Fairfield Inn By Marriott Evansville East
La Quinta Inn & Suites by Wyndham Evansville

La Quinta Inn & Suites by Wyndham Evansville

3 out of 5
8015 East Division Street Evansville IN
  • 4 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
Check in was very easy. I got to the room and there was a hot pocket wrapper stuffed by the box spring/headboard. Lots of hair everywhere, chair was ripped up and had stains all over it, shower curtain was dirty, ac smelt like a wet dog. Our room keys stopped working everyday so we had to go ge then ...

Reviewed on Feb 24, 2026

La Quinta Inn & Suites by Wyndham Evansville
Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

3 out of 5
100 Cross Pointe Blvd Evansville IN
  • 4 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
The staff was Top Notch, Love the dinner snacks and drinks! Would definitely stay again.

Reviewed on Feb 28, 2026

Drury Inn & Suites Evansville East
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in New Albany. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (771 reviews)
Great room, clean, and breakfast was really good with selection and quality!

Reviewed on Feb 28, 2026

Hampton Inn New Albany Louisville West
Hyatt Place Evansville

Hyatt Place Evansville

3 out of 5
202 Se 2nd St Evansville IN
  • 5 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
I had a great time but check in was at 3pm my room wasn’t ready until 4pm n the reception had the nerve to have an attitude/ wanna be smart..

Reviewed on Feb 24, 2026

Hyatt Place Evansville
DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

4 out of 5
601 Walnut Street Evansville IN
  • 5 hours drive from KFC Yum Center
Book a stay at this business-friendly hotel in Evansville. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.6/10 Excellent! (1,002 reviews)
I recently stayed here in Evansville for five days for my son’s birthday, and unfortunately, the experience was disappointing overall. Before arrival, I called to ask if they offered anything small for birthdays (I even said I didn’t mind paying for something simple like a balloon that said “Happy ...

Reviewed on Feb 28, 2026

DoubleTree by Hilton Evansville
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
  • 16 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.6/10 Exceptional! (448 reviews)
The staff was great and room was clean and very nice.

Reviewed on Feb 24, 2026

Hilton Garden Inn Jeffersonville Louisville North
Hampton Inn Louisville-North/Clarksville

Hampton Inn Louisville-North/Clarksville

2.5 out of 5
1501 Broadway Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Hampton Inn Louisville-North/Clarksville
Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North

2.5 out of 5
1485 Broadway St Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,000 reviews)
Clean. Great staff

Reviewed on Feb 26, 2026

Comfort Inn & Suites Clarksville - Louisville North
Motel 6 Jeffersonville, In - Louisville

Motel 6 Jeffersonville, In - Louisville

2 out of 5
2012 Hospitality Way Clarksville IN
  • 7 min drive from KFC Yum Center
Stay at this motel in Clarksville. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Our guests praise the clean rooms in our reviews. Popular ...
6/10 (389 reviews)
The room was clean ......they welcomed my fur baby ....the staff was helpful

Reviewed on Feb 26, 2026

Motel 6 Jeffersonville, In - Louisville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southern Indiana

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Indiana.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Indiana’s 1,635 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $53. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southern Indiana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Indiana. No matter your reason for visiting Southern Indiana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southern Indiana hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southern Indiana for as low as $53.

How many hotels are there in Southern Indiana?

With over 1,635 hotels in Southern Indiana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $53.

How to find cheap car rentals in Southern Indiana?

Finding a cheap car rental deal in Southern Indiana is as easy as scoring cheap hotels in Southern Indiana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.