Hotels Near
West Main Historic District

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Featured West Main Historic District Hotels

Omni Louisville Hotel
Omni Louisville Hotel
4 out of 5
400 S. 2nd Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Louisville. Enjoy a full-service spa, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,307 reviews)
"Just entering through the enormous wooden double front doors you step into Omni’s Kentucky and you don’t want to leave."

Reviewed on Feb 21, 2025

Omni Louisville Hotel
Galt House Hotel Trademark Collection by Wyndham
Galt House Hotel Trademark Collection by Wyndham
4 out of 5
140 North Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the restaurant and the helpful staff in ...
8.8/10 Excellent! (3,427 reviews)
"Poor breakfast. Everything else was great"

Reviewed on Feb 17, 2025

Galt House Hotel Trademark Collection by Wyndham
Holiday Inn Express & Suites Louisville Downtown, an IHG Hotel
Holiday Inn Express & Suites Louisville Downtown, an IHG Hotel
2.5 out of 5
800 W Market St, Louisville, KY
Fully refundable
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,416 reviews)
Ok - Quick overnight stay for Family of 5
"We had a quick overnight stay for my family of 5. The room was acceptable, but there were a few minor things here and there that stood out, all in the bathroom. Room was booked for 5 people, bathroom was stocked with 3 towels and 2 washcloths. Hair in the tub and sink, body soap not refilled and ..."

Reviewed on Feb 20, 2025

Holiday Inn Express & Suites Louisville Downtown, an IHG Hotel
Cambria Hotel Louisville Downtown-Whiskey Row
Cambria Hotel Louisville Downtown-Whiskey Row
3 out of 5
120 SOUTH FLOYD ST, Louisville, KY
Fully refundable
Stay at this 3-star business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.2/10 Wonderful! (885 reviews)
Accommodating and Comfortable
"Great staff here making sure you’re comfortable. Room is spacious with a nice view, it sits on the western side of whiskey row but walkable."

Reviewed on Feb 18, 2025

Cambria Hotel Louisville Downtown-Whiskey Row
Holiday Inn Louisville Downtown, An Ihg Hotel
Holiday Inn Louisville Downtown, An Ihg Hotel
3 out of 5
101 W. Muhammad Ali Blvd, Louisville, KY
Fully refundable
Stay at this 3-star hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (478 reviews)
"Close to our destination the U of L hospital"

Reviewed on Feb 12, 2025

Holiday Inn Louisville Downtown, An Ihg Hotel
SpringHill Suites by Marriott Louisville Downtown
SpringHill Suites by Marriott Louisville Downtown
3 out of 5
132 E Jefferson Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,004 reviews)
"I was in town for a death in the family. Room was ok. Very noisy at night, lobby was chaotic and parking was a mess. They had my husband park at a pawn shop."

Reviewed on Feb 21, 2025

SpringHill Suites by Marriott Louisville Downtown
Aloft Louisville Downtown
Aloft Louisville Downtown
3 out of 5
102 West Main Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,003 reviews)
"Nice"

Reviewed on Feb 21, 2025

Aloft Louisville Downtown
Moxy Louisville Downtown
Moxy Louisville Downtown
3.5 out of 5
100 West Washington Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the bar ...
9/10 Wonderful! (583 reviews)
"Very cozy setup"

Reviewed on Feb 21, 2025

Moxy Louisville Downtown
Hyatt Regency Louisville
Hyatt Regency Louisville
4 out of 5
320 West Jefferson Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,003 reviews)
"I have no complaints! It was the perfect place to stay for an event at the Yum! Center"

Reviewed on Feb 19, 2025

Hyatt Regency Louisville
Fairfield Inn & Suites by Marriott Louisville Downtown
Fairfield Inn & Suites by Marriott Louisville Downtown
2.5 out of 5
100 E Jefferson Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,002 reviews)
Good, not great
"Great location for a business conference at the KICC. Most everything was good, but with staying 4 nights, we constantly had to ask for fresh towels and washcloths, and to have the garbage emptied. And it was never handled promptly, if at all. That was pretty disappointing."

Reviewed on Feb 19, 2025

Fairfield Inn & Suites by Marriott Louisville Downtown
21c Museum Hotel Louisville
21c Museum Hotel Louisville
4.5 out of 5
700 W Main Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Louisville. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
9.2/10 Wonderful! (1,002 reviews)
"Unique designs, loved the room - very comfortable"

Reviewed on Feb 17, 2025

21c Museum Hotel Louisville
Towneplace Suites By Marriott Louisville Downtown
Towneplace Suites By Marriott Louisville Downtown
3 out of 5
801 WEST JEFFERSON STREET, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Louisville. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the helpful staff in our ...
9/10 Wonderful! (292 reviews)
"It was very neat and organized place to stay. The rooms were very clean and the breakfast was awesome."

Reviewed on Feb 23, 2025

Towneplace Suites By Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in West Main Historic District

Louisville is a city that has a lot going on, but you have your sights set on West Main Historic District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that West Main Historic District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of West Main Historic District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Louisville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the West Main Historic District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the West Main Historic District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of West Main Historic District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in West Main Historic District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $88
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the West Main Historic District hotel you want, book it, and never look back. Because your great escape is ahead of you.