Hotels Near
West Main Historic District

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Featured West Main Historic District Hotels

Galt House Hotel Trademark Collection by Wyndham
Galt House Hotel Trademark Collection by Wyndham
4 out of 5
140 North Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the restaurant and the helpful staff in ...
8.8/10 Excellent! (3,425 reviews)
"Gorgeous property downtown"

Reviewed on Jul 9, 2025

Galt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel
Omni Louisville Hotel
4 out of 5
400 S. 2nd Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Louisville. Enjoy a full-service spa, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,511 reviews)
"Perfect"

Reviewed on Jul 7, 2025

Omni Louisville Hotel
Holiday Inn Express & Suites Louisville Downtown by IHG
Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 out of 5
800 W Market St, Louisville, KY
Fully refundable
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,483 reviews)
"Close to slugger factory east parking"

Reviewed on Jul 9, 2025

Holiday Inn Express & Suites Louisville Downtown by IHG
Cambria Hotel Louisville Downtown-Whiskey Row
Cambria Hotel Louisville Downtown-Whiskey Row
3 out of 5
120 SOUTH FLOYD ST, Louisville, KY
Fully refundable
Stay at this 3-star business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.2/10 Wonderful! (1,011 reviews)
"Thankful and this place is one of kind. #boutique hotel"

Reviewed on Jul 10, 2025

Cambria Hotel Louisville Downtown-Whiskey Row
Homewood Suites by Hilton Louisville Downtown, KY
Homewood Suites by Hilton Louisville Downtown, KY
3 out of 5
635 W Market St, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (1,009 reviews)
Good location and clean
"Good place to stay downtown. Located near Mitchners and Evan Williams. One block from Louisville Slugger museum"

Reviewed on Jul 7, 2025

Homewood Suites by Hilton Louisville Downtown, KY
Embassy Suites Louisville Downtown
Embassy Suites Louisville Downtown
4 out of 5
501 South Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Louisville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,008 reviews)
"Nice hotel . Clean. Small room"

Reviewed on Jul 9, 2025

Embassy Suites Louisville Downtown
21c Museum Hotel Louisville
21c Museum Hotel Louisville
4.5 out of 5
700 W Main Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Louisville. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
21c is Amazing
"The hotel and the hotel staff were both excellent. We appreciated the friendliness of every staff member we encountered and the aesthetics of the entire hotel. Our room was very clean, comfortable, appealing and so quiet. We were very pleased with our stay."

Reviewed on Jul 7, 2025

21c Museum Hotel Louisville
Aloft Louisville Downtown
Aloft Louisville Downtown
3 out of 5
102 West Main Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,007 reviews)
"The room and lobby was quirky. Very nice property. Will definitely be staying again."

Reviewed on Jul 6, 2025

Aloft Louisville Downtown
Hyatt Regency Louisville
Hyatt Regency Louisville
4 out of 5
320 West Jefferson Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,001 reviews)
Excellent stay.
"Excellent service. Friendly and professional staff."

Reviewed on Jul 1, 2025

Hyatt Regency Louisville
Towneplace Suites By Marriott Louisville Downtown
Towneplace Suites By Marriott Louisville Downtown
3 out of 5
801 WEST JEFFERSON STREET, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the ...
9/10 Wonderful! (409 reviews)
"This is our go to stay whenever we're in town. Clean, convenient, great rooms and amenities."

Reviewed on Jul 6, 2025

Towneplace Suites By Marriott Louisville Downtown
Holiday Inn Louisville Downtown by IHG
Holiday Inn Louisville Downtown by IHG
3 out of 5
101 W. Muhammad Ali Blvd, Louisville, KY
Fully refundable
Stay at this 3-star hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (590 reviews)
"The property was clean and seemed newer. The staff were very friendly. The breakfast was tasty. The king standard room was quite small. If I was staying more than one night, I would look for larger options. Convenient walk to Fourth St and dining options."

Reviewed on Jul 6, 2025

Holiday Inn Louisville Downtown by IHG
Hilton Garden Inn Louisville Downtown
Hilton Garden Inn Louisville Downtown
3.5 out of 5
350 West Chestnut Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
8.4/10 Very Good! (1,001 reviews)
"Nice people"

Reviewed on Jul 2, 2025

Hilton Garden Inn Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in West Main Historic District

Louisville is a city that has a lot going on, but you have your sights set on West Main Historic District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that West Main Historic District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of West Main Historic District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Louisville so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the West Main Historic District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the West Main Historic District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of West Main Historic District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in West Main Historic District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $92
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the West Main Historic District hotel you want, book it, and never look back. Because your great escape is ahead of you.