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Spa Resort Hotels in West Main Historic District

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Featured West Main Historic District Resorts & Hotels with Spas

Galt House Hotel Trademark Collection by Wyndham
Galt House Hotel Trademark Collection by Wyndham
4 out of 5
140 North Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the restaurant and the helpful staff in ...
Galt House Hotel Trademark Collection by Wyndham
21c Museum Hotel Louisville
21c Museum Hotel Louisville
4.5 out of 5
700 W Main Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Louisville. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
21c Museum Hotel Louisville
Louisville Marriott Downtown
Louisville Marriott Downtown
4 out of 5
280 West Jefferson Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Louisville. Enjoy breakfast (surcharge), a 24-hour health club, and valet parking (surcharge). Our guests praise ...
Louisville Marriott Downtown
Residence Inn by Marriott Louisville Downtown
Residence Inn by Marriott Louisville Downtown
3 out of 5
333 East Market Street, Louisville, KY
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Residence Inn by Marriott Louisville Downtown
Seelbach Hilton Louisville Downtown
Seelbach Hilton Louisville Downtown
4 out of 5
500 S 4th St, Louisville, KY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Louisville. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise ...
Seelbach Hilton Louisville Downtown
See all 1,969 properties in West Main Historic District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.