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Spa Resort Hotels in West Main Historic District

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Featured West Main Historic District Resorts & Hotels with Spas

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
Galt House Hotel Trademark Collection by Wyndham
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 out of 5
700 W Main Street Louisville KY
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Louisville. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
21c Museum Hotel Louisville
Louisville Marriott Downtown

Louisville Marriott Downtown

4 out of 5
280 West Jefferson Street Louisville KY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Louisville. Enjoy breakfast (surcharge), a 24-hour health club, and valet parking (surcharge). Our guests praise ...
Louisville Marriott Downtown
Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown

3 out of 5
333 East Market Street Louisville KY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Residence Inn by Marriott Louisville Downtown
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

4 out of 5
500 S 4th St Louisville KY
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Louisville. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise ...
Seelbach Hilton Louisville Downtown
See all 2,081 properties in West Main Historic District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.