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Hotels in Laguna Niguel

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Embassy Suites by Hilton Irvine Orange County Airport

Embassy Suites by Hilton Irvine Orange County Airport

3.5 out of 5
2120 Main St Irvine CA
  • 26 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Irvine. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,472 reviews)
It was nice. The room was spacious and clean. I like the high floors. I would definitely go back to this hotel.

Reviewed on Jan 21, 2026

Embassy Suites by Hilton Irvine Orange County Airport
Hotel Fera Anaheim, a DoubleTree by Hilton

Hotel Fera Anaheim, a DoubleTree by Hilton

4 out of 5
100 The City Dr S Orange CA
  • 44 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Orange. Enjoy 2 outdoor pickleball courts, breakfast (surcharge), and room service. Our guests praise the restaurant ...
8.6/10 Excellent! (3,834 reviews)
stayed for a night for a gathering in town ! Absolutely loved my stay will chose Hotel Fera in the future again !

Reviewed on Jan 19, 2026

Hotel Fera Anaheim, a DoubleTree by Hilton
Renaissance Newport Beach Hotel

Renaissance Newport Beach Hotel

4 out of 5
4500 Macarthur Blvd Newport Beach CA
  • 24 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Newport Beach. Enjoy a free airport shuttle, room service, and a 24-hour fitness center. Our guests praise the ...
8.8/10 Excellent! (1,005 reviews)
I love it

Reviewed on Jan 9, 2026

Renaissance Newport Beach Hotel
Holiday Inn Santa Ana Orange County Airport by IHG

Holiday Inn Santa Ana Orange County Airport by IHG

3 out of 5
2726 S Grand Ave Santa Ana CA
  • 30 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,181 reviews)
It was ok

Reviewed on Jan 22, 2026

Holiday Inn Santa Ana Orange County Airport by IHG
Ayres Hotel Costa Mesa/Newport Beach

Ayres Hotel Costa Mesa/Newport Beach

4 out of 5
325 Bristol Street Costa Mesa CA
  • 25 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Costa Mesa. Enjoy free WiFi, 2 outdoor pools, and a free airport shuttle. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,031 reviews)
I would 100% stay at this hotel again. The rooms are very large, the bed is comfortable, and everything was exceptionally clean. The staff was friendly and welcoming, and the hotel offered all the amenities you need for the price. I travel frequently for work and stay in hotels across the United ...

Reviewed on Jan 22, 2026

Ayres Hotel Costa Mesa/Newport Beach
Laguna Hills Lodge

Laguna Hills Lodge

2.5 out of 5
23932 Paseo De Valencia Laguna Hills CA
  • 11 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Laguna Hills. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (2,827 reviews)
It is in a convenient location.

Reviewed on Jan 21, 2026

Laguna Hills Lodge
Ayres Hotel Orange

Ayres Hotel Orange

3.5 out of 5
200 N. The City Drive Orange CA
  • 44 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Orange. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the restaurant ...
9.6/10 Exceptional! (2,568 reviews)
Clean room

Reviewed on Jan 21, 2026

Ayres Hotel Orange
Sonesta Irvine John Wayne Airport

Sonesta Irvine John Wayne Airport

3.5 out of 5
17941 Von Karman Avenue Irvine CA
  • 25 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Irvine. Enjoy breakfast (surcharge), a free airport shuttle, and a fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (1,059 reviews)
Clean and spacious room, excellent staff and great restaurant fare. Small but well appointed fitness center.

Reviewed on Jan 21, 2026

Sonesta Irvine John Wayne Airport
Embassy Suites by Hilton Santa Ana Orange County Airport

Embassy Suites by Hilton Santa Ana Orange County Airport

3.5 out of 5
1325 East Dyer Road Santa Ana CA
  • 29 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, a free airport shuttle, and room service. Our guests praise the breakfast and ...
6.2/10 (1,853 reviews)
Clean room, great staff

Reviewed on Jan 19, 2026

Embassy Suites by Hilton Santa Ana Orange County Airport
MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

2.5 out of 5
2701 Hotel Terrace Santa Ana CA
  • 30 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,565 reviews)
Most everything was good! Breakfast was really good and the WiFi was really bad! Looks like the WiFi has had problems for awhile now, looking at past reviews. Would stay here again if tge WiFi issue is resolved.

Reviewed on Jan 23, 2026

MainStay Suites John Wayne Airport by Choice Hotels
Pendry Newport Beach

Pendry Newport Beach

4.5 out of 5
690 Newport Center Dr Newport Beach CA
  • 19 min drive from Orange County Natural History Museum
Book a stay at this luxury hotel in Newport Beach. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.2/10 Wonderful! (478 reviews)
Beautiful, clean, and the highest level service. Thank you to the staff!

Reviewed on Jan 22, 2026

Pendry Newport Beach
Best Western Plus Meridian Inn & Suites, Anaheim-Orange

Best Western Plus Meridian Inn & Suites, Anaheim-Orange

2.5 out of 5
720 The City Drive S Orange CA
  • 41 min drive from Orange County Natural History Museum
Book a stay at this business-friendly hotel in Orange. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,001 reviews)
Great rooms! Nice breakfasts and great staff.

Reviewed on Jan 21, 2026

Best Western Plus Meridian Inn & Suites, Anaheim-Orange
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Laguna Niguel

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $100. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Laguna Niguel hotel deals at the last minute.

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Frequently Asked Questions About Laguna Niguel hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Laguna Niguel?

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How to find cheap car rentals in Laguna Niguel?

Finding a cheap car rental deal in Laguna Niguel is as easy as scoring cheap hotels in Laguna Niguel. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.