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Hotels in Lignumvitae Key Botanical State Park

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Cheeca Lodge & Spa

Cheeca Lodge & Spa

5 out of 5
81801 Overseas Highway, Mile Marker 82 Islamorada FL
  • 10 min drive from Indian Key Historic State Park
Book a stay at this luxury resort in Islamorada. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (1,311 reviews)
"Much batter than bigger hotels we were used to staying at. Staff was great and everything felt more purposeful and curated."

Reviewed on May 30, 2026

Cheeca Lodge & Spa
Chesapeake Beach Resort

Chesapeake Beach Resort

3.5 out of 5
83409 Overseas Hwy Islamorada FL
  • 14 min drive from Indian Key Historic State Park
Book a stay at this beach hotel in Islamorada. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the breakfast and the pool in our reviews. ...
9.2/10 Wonderful! (1,733 reviews)
"Property was clean and very smooth check in process. I would definitely return."

Reviewed on May 31, 2026

Chesapeake Beach Resort
Waterside Suites & Marina

Waterside Suites & Marina

3.5 out of 5
201 Ocean Drive Key Largo FL
  • 54 min drive from Indian Key Historic State Park
Stay at this hotel in Key Largo. Enjoy free WiFi, a marina, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,372 reviews)
"Very nice space, great view of the marina and passing boats, plenty of room for two guests, all the amenities you should need, clean, working thermostat, nice staff. Overall, an excellent stay that gives you all you need and more!"

Reviewed on May 31, 2026

Waterside Suites & Marina
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

2 out of 5
527 Caribbean Drive Key Largo FL
  • 54 min drive from Indian Key Historic State Park
Stay at this hotel in Key Largo. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
8.6/10 Excellent! (1,804 reviews)
"Angela, staff.member in the lobby, excellent and helpful"

Reviewed on May 31, 2026

Marina Del Mar Resort and Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
  • 46 min drive from Indian Key Historic State Park
Book a stay at this beach resort in Key Largo. Enjoy 2 outdoor pools, 2 restaurants, and a private beach. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,077 reviews)
"Excellent"

Reviewed on Jun 1, 2026

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
  • 10 min drive from Indian Key Historic State Park
Book a stay at this beach hotel in Islamorada. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,021 reviews)
"Pool was very dirty, rooms super clean and look great"

Reviewed on May 31, 2026

Islander Resort
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
  • 24 min drive from Indian Key Historic State Park
Book a stay at this beach resort in Long Key. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,291 reviews)
"One of the best hotel experiences we’ve ever had. I cannot recommend this place enough. It’s a little slice of heaven. We will be traveling back to the Keys just to stay at this place again. It was the best part of our entire trip by far. Just plan your meals out! There isn’t a ton of dining in this ..."

Reviewed on May 31, 2026

Lime Tree Bay Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
  • 5 min drive from Indian Key Historic State Park
Book a stay at this beach resort in Islamorada. Enjoy 2 restaurants, a private beach, and 3 bars/lounges. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,286 reviews)
"Good place to stay, very friendly staff and great breakfast!"

Reviewed on May 31, 2026

Amara Cay Resort
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

4 out of 5
84001 Overseas Hwy Islamorada FL
  • 16 min drive from Indian Key Historic State Park
Book a stay at this beach resort in Islamorada. Enjoy free WiFi, 3 outdoor pools, and 4 restaurants. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (202 reviews)
"The property was beautiful as soon as we pulled up we were greeted by a woman on a golf cart. She was so happy and helpful. It made us feel comfortable right away, showed us to the front desk and she was also so very friendly. I wish I remembered their names. We got an ocean view. It also overlooked ..."

Reviewed on May 30, 2026

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
  • 41 min drive from Indian Key Historic State Park
Book a stay at this luxury hotel in Marathon. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,008 reviews)
"Let’s start by saying I gave them months in advance that we were coming and plans and they managed to not fulfill their part of the deal. I paid for extra amenities to be delivered to the room before we got there for my in-laws 52nd anniversary. they fixed it still charged me ice machine didn’t work ..."

Reviewed on May 26, 2026

Hawks Cay Resort
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

3 out of 5
99701 Overseas Hwy Key Largo FL
  • 53 min drive from Indian Key Historic State Park
Book a stay at this beach hotel in Key Largo. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,054 reviews)
"Everything about our stay was perfect. The best part about it was the amazing heated pool. I totally recommend staying there.. it’s a great location close to everything"

Reviewed on May 31, 2026

Holiday Inn Key Largo by IHG
Bayside Inn Key Largo

Bayside Inn Key Largo

3 out of 5
99490 Overseas Hwy Key Largo FL
  • 53 min drive from Indian Key Historic State Park
Book a stay at this beach hotel in Key Largo. Enjoy free WiFi, free parking, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,748 reviews)
"Very clean, but there was a mildew smell in our room we couldn’t identify where it was coming from. Staff was friendly. Air very cold in the Florida heat. The walkways outside the room are VERY slick when wet so be careful. Loved the amenities and views - waking up or seeing sunset at their beach/pool ..."

Reviewed on May 31, 2026

Bayside Inn Key Largo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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