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Featured Medical Center Hotels

Hollywood Casino at Greektown
The hotel itself was great, with the added bonus of direct access to the casino, which was very convenient. Close to all the sports venues, being less that 10 min walk away. However, at the time of our stay, most of the surrounding streets were either closed or under construction, which made getting ...
Reviewed on Oct 18, 2025

MotorCity Casino Hotel
Super clean. Loved it.
Reviewed on Oct 18, 2025

Fort Pontchartrain Detroit, a Wyndham Hotel
Parking options are limited, but the overall accommodations were lovely.
Reviewed on Oct 18, 2025

Atheneum Suite Hotel
Our suite was lovely. Very clean. Comfortable beds. Very nice bathroom. The hotel itself was also clean, updated with nice bar and choice of restaurants. The area around the hotel was pleasant. Our room overlooked a small park at the entrance of the hotel. The staff was great. Friendly, helpful and ...
Reviewed on Oct 17, 2025

The Siren Hotel, an Ash Hotel
My stay at The Siren Hotel was fabulous! It is so unique and moody in all areas of the hotel. I especially loved their customer service and amazing hotel signature scent!
Reviewed on Oct 18, 2025

Radisson Hotel Detroit Metro Airport
Room was good for quick overnight stay
Reviewed on Oct 19, 2025

Sonder by Marriott Bonvoy Gabriel Richard Apartments Downtown
This place was amazing! The room itself was beautiful. We loved the view! I think we would have loved a recommendation of where to park since we were not from the area. Other than that, we enjoyed this area! It was walkable, and shopping and restaurants was only about a 10 min walk from the ...
Reviewed on Oct 18, 2025

Hotel Indigo Detroit Downtown by IHG
Heart of downtown. Walkable to many places.
Reviewed on Oct 22, 2025

Trumbull and Porter Hotel
Very nice, courteous staff
Reviewed on Oct 17, 2025

Skyline Hotel Detroit Airport, SureStay Collection by BW
Nice staff, close to airport with free shuttle
Reviewed on Oct 14, 2025

MGM Grand Detroit
Easy access on/off the interstate. Excellent location for easy walking to sport venues.
Reviewed on Oct 16, 2025

Baymont by Wyndham Downtown Detroit
Clean room nice staff free parking
Reviewed on Oct 17, 2025
Hotels in Medical Center
Detroit is a city that has a lot going on, but you have your sights set on Medical Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical Center hotels that will do the trick.
A beautiful day in the neighborhood
As much as you like getting out there, it’s also good to know a part of Detroit so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical Center underground. What’s a journey without a good story to go with it?
Beyond the block
We’re not talking about the Medical Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:
- Hotwire Hot Rate: Snag some of the best hotels in Medical Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
- Price: You have a price in mind, and we have solutions. Hotels start as low as $85
- Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.
Find the Medical Center hotel you want, book it, and never look back. Because your great escape is ahead of you.
Hotels by Star Rating
Top Attractions in Medical Center
- Hotels near Lexus Velodrome (0.29 mi)
- Hotels near Henry Ford Museum (9.8 mi)
- Hotels near Huntington Place (1.95 mi)
- Hotels near MGM Grand Detroit Casino (1.46 mi)
- Hotels near Comerica Park (1.1 mi)
- Hotels near Ford Field (1.12 mi)
- Hotels near Hollywood Casino at Greektown (1.54 mi)
- Hotels near GM Renaissance Center (1.92 mi)
- Hotels near Little Caesars Arena (0.94 mi)
- Hotels near Fox Theatre (1.12 mi)
- Hotels near Greenfield Village (9.59 mi)
- Hotels near MotorCity Casino (1.23 mi)
- Hotels near Detroit Zoo (9.91 mi)
- Hotels near Detroit Masonic Temple (0.92 mi)
- Hotels near Wayne State University (0.84 mi)
- Hotels near Fillmore Detroit (1.18 mi)
- Hotels near Detroit Institute of Arts (0.59 mi)
- Hotels near Somerset Collection (15.73 mi)
- Hotels near University of Michigan Dearborn (9.53 mi)
Cities near Medical Center
- Windsor Hotels (2.9 mi)
- Dearborn Hotels (6.58 mi)
- Southfield Hotels (11.82 mi)
- Troy Hotels (18.05 mi)
- Romulus Hotels (19.7 mi)
- Warren Hotels (11.23 mi)
- Livonia Hotels (15.22 mi)
- Sterling Heights Hotels (15.7 mi)
- Royal Oak Hotels (10.37 mi)
- Farmington Hills Hotels (18.8 mi)
- Utica Hotels (18.78 mi)
- Birmingham Hotels (15.47 mi)
- Rochester Hotels (22.86 mi)
- Taylor Hotels (13.48 mi)
- Ferndale Hotels (8.37 mi)
- Roseville Hotels (11.54 mi)
- Madison Heights Hotels (9.42 mi)
- Allen Park Hotels (10.41 mi)
- Bloomfield Hills Hotels (18.55 mi)
- Westland Hotels (17.74 mi)