Hotels Near
Medical Center

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Featured Medical Center Hotels

La Quinta Inn & Suites by Wyndham Detroit Metro Airport
La Quinta Inn & Suites by Wyndham Detroit Metro Airport
3 out of 5
30847 Flynn Drive, Romulus, MI
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Romulus. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and ...
8/10 Very Good! (1,702 reviews)
"Found a clean room. Front desk folks were welcoming."

Reviewed on Jun 6, 2024

La Quinta Inn & Suites by Wyndham Detroit Metro Airport
Hollywood Casino at Greektown
Hollywood Casino at Greektown
4 out of 5
1200 Saint Antoine St, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Detroit. Enjoy 5 restaurants, a casino, and 5 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,506 reviews)
"Casino"

Reviewed on Jun 5, 2024

Hollywood Casino at Greektown
Fort Pontchartrain Detroit, a Wyndham Hotel
Fort Pontchartrain Detroit, a Wyndham Hotel
3.5 out of 5
2 Washington Blvd, Detroit, MI
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Detroit. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the ...
7.6/10 Good! (1,758 reviews)
"Fantastic stay. Great location, clean, hospitable hotel. Great service. Clean room. Can't complain at all. It was great!"

Reviewed on Jun 4, 2024

Fort Pontchartrain Detroit, a Wyndham Hotel
MotorCity Casino Hotel
MotorCity Casino Hotel
4.5 out of 5
2901 Grand River Ave, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Detroit. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (3,207 reviews)
"Noise. Early Sunday morning 6.2.24 There was a very loud argument between a man and a woman on the fourth or fifth floor. Both were screaming and it went on for about 45 minutes. There was a loud banging sound too. Hopefully no one was injured during this incident."

Reviewed on Jun 3, 2024

MotorCity Casino Hotel
The Godfrey Detroit, Curio Collection By Hilton
The Godfrey Detroit, Curio Collection By Hilton
5 out of 5
1401 Michigan Avenue, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Detroit. Enjoy free WiFi, 2 restaurants, and 3 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (738 reviews)
"Overall beautiful building quite a hidden gem"

Reviewed on Jun 4, 2024

The Godfrey Detroit, Curio Collection By Hilton
Atheneum Suite Hotel
Atheneum Suite Hotel
4 out of 5
1000 Brush Avenue, Detroit, MI
Book a stay at this boutique hotel in Detroit. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the bar and the helpful staff ...
9/10 Wonderful! (1,372 reviews)
"The hotel was beautiful and clean, the room was spacious, and the staff was very friendly. We enjoyed the food and drinks and were impressed with our room and the rest of the hotel. Two issues to consider: 1. We stayed in a room facing a nightclub, and the noise was outrageous half the night. We'll ..."

Reviewed on May 26, 2024

Atheneum Suite Hotel
The Siren Hotel
The Siren Hotel
3.5 out of 5
1509 Broadway St., Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in Detroit. Enjoy free WiFi, 2 restaurants, and 4 bars/lounges. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.6/10 Excellent! (1,211 reviews)
"Wonderful staff and a beautiful property. We stayed in the bunkbed room which was perfect for two adults going to a concert. They even have little privacy curtains that you can pull closed, and outlets for both the top and bottom bunk. We grabbed a cocktail at the bar, Candy Bar which was beautiful ..."

Reviewed on May 30, 2024

The Siren Hotel
MGM Grand Detroit
MGM Grand Detroit
4.5 out of 5
1777 3rd Street, Detroit, MI
Stay at this 4.5-star luxury hotel in Detroit. Enjoy free parking, a full-service spa, and 8 restaurants. Our guests praise the restaurant and the helpful staff ...
8.2/10 Very Good! (1,025 reviews)
"Easy check in free valet. Able to upgrade to wellness floor. Room view was great. Very nice lady at check in."

Reviewed on Jun 4, 2024

MGM Grand Detroit
The Westin Southfield Detroit
The Westin Southfield Detroit
4 out of 5
1500 Town Center, Southfield, MI
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Southfield. Enjoy breakfast (surcharge), room service, and a health club. Our guests praise the restaurant and ...
8/10 Very Good! (1,017 reviews)
Enjoyable stay
"Very friendly and helpful staff. Lovely clean room, spacious. Boring view of back parking garage roofs. I came from IL and Google maps did have some issues navigating because the hotel is one of several buildings in a large center w many parking garages plus on a one way street. Nice restaurant with ..."

Reviewed on Jun 3, 2024

The Westin Southfield Detroit
Sonder Gabriel Richard
Sonder Gabriel Richard
3.5 out of 5
305 Michigan Avenue, Detroit, MI
Stay at this 3.5-star aparthotel in Detroit. Enjoy a fitness center, concierge services, and in-room washers/dryers. Our guests praise the helpful staff and ...
8.8/10 Excellent! (765 reviews)
"Everything I needed. I will be staying at a Sonder location every chance I get. Great value."

Reviewed on Jun 4, 2024

Sonder Gabriel Richard
Shinola Hotel
Shinola Hotel
4 out of 5
1400 Woodward Ave, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Detroit. Enjoy free WiFi, 4 restaurants, and 2 bars/lounges. Our guests praise the restaurant and the helpful ...
9.4/10 Exceptional! (1,004 reviews)
"Clean and very convenient location"

Reviewed on Jun 3, 2024

Shinola Hotel
ROOST Detroit
ROOST Detroit
4 out of 5
1265 Washington Blvd, Detroit, MI
Fully refundableReserve now, pay when you stay
Stay at this 4-star aparthotel in Detroit. Enjoy free WiFi, 2 restaurants, and 4 bars/lounges. Popular attractions MGM Grand Detroit Casino and Ford Field are ...
9.8/10 Exceptional! (228 reviews)
Really amazing.
"Amazing hotel. The front desk staff was excellent. I think it was Ben? Thank you! Loved the stay."

Reviewed on Jun 4, 2024

ROOST Detroit
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Medical Center

Detroit is a city that has a lot going on, but you have your sights set on Medical Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Medical Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Medical Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Detroit so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Medical Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Medical Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Medical Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Medical Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $85
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Medical Center hotel you want, book it, and never look back. Because your great escape is ahead of you.