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Midtown

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Featured Midtown Hotels

Holiday Inn Fort Myers - Downtown Area by IHG
Holiday Inn Fort Myers - Downtown Area by IHG
3 out of 5
2431 Cleveland Ave, Fort Myers, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,002 reviews)
"The property is under remodel but still clean and well taken care of. The room was basic queen, clean and comfortable for a few nights of local restaurants in the area as well an"

Reviewed on Mar 21, 2025

Holiday Inn Fort Myers - Downtown Area by IHG
Margaritaville Beach Resort Fort Myers
Margaritaville Beach Resort Fort Myers
4 out of 5
251 Crescent Street, Fort Myers Beach, FL
Stay at this 4-star beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (954 reviews)
Quick Couple Get Away
"Quick 2 night get away. Dog friendly. Easy to walk to bars/restaurants. Loved the atmosphere. Everyone so friendly."

Reviewed on Mar 26, 2025

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort
Lani Kai Beachfront Resort
3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star beach hotel in Fort Myers Beach. Enjoy free WiFi, an outdoor pool, and a beach locale. Popular attractions Key West Express and Times Square ...
8.4/10 Very Good! (1,005 reviews)
"Location"

Reviewed on Mar 26, 2025

Lani Kai Beachfront Resort
Marriott Sanibel Harbour Resort & Spa
Marriott Sanibel Harbour Resort & Spa
4 out of 5
17260 Harbour Pointe Dr, Fort Myers, FL
Fully refundableReserve now, pay when you stay
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.2/10 Very Good! (1,001 reviews)
"Loved it"

Reviewed on Mar 24, 2025

Marriott Sanibel Harbour Resort & Spa
Pink Shell Beach Resort and Marina
Pink Shell Beach Resort and Marina
4 out of 5
275 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
Stay at this 4-star beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools, and 3 restaurants. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (1,005 reviews)
"Great staff. Very well run."

Reviewed on Mar 27, 2025

Pink Shell Beach Resort and Marina
Sanibel Island Beach Resort
Sanibel Island Beach Resort
3 out of 5
1231 Middle Gulf Dr, Sanibel, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
8.8/10 Excellent! (1,076 reviews)
"Had same house keeper the entire time. Not only did she do an amazing job cleaning up after we had been at the beach with all the sand mess and eating in the room. But she was very nice getting us other things we needed, like extra coffee pods, cups, towels, or anything else. Super friendly and ..."

Reviewed on Mar 26, 2025

Sanibel Island Beach Resort
Hyatt Place Fort Myers/at The Forum
Hyatt Place Fort Myers/at The Forum
3 out of 5
2600 Champion Ring Rd, Fort Myers, FL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,002 reviews)
"Close to airport and close to ball fields"

Reviewed on Mar 24, 2025

Hyatt Place Fort Myers/at The Forum
Edison Beach House
Edison Beach House
3.5 out of 5
830 Estero Blvd., Fort Myers Beach, FL
Stay at this 3.5-star beach aparthotel in Fort Myers Beach. Enjoy free parking, a beach locale, and daily housekeeping. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,278 reviews)
"Loved the beach view."

Reviewed on Mar 27, 2025

Edison Beach House
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
2.5 out of 5
20091 Summerlin Road, Fort Myers, FL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
7.2/10 Good! (1,006 reviews)
"Perfect getaway !"

Reviewed on Mar 26, 2025

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Holiday Inn Express & Suites Fort Myers Airport by IHG
Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 out of 5
14567 GLOBAL PARKWAY, Fort Myers, FL
Fully refundable
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (822 reviews)
"Friendly. Clean, quiet"

Reviewed on Mar 28, 2025

Holiday Inn Express & Suites Fort Myers Airport by IHG
Embassy Suites by Hilton Fort Myers Estero
Embassy Suites by Hilton Fort Myers Estero
3.5 out of 5
10450 Corkscrew Commons Dr, Estero, FL
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Estero. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (1,008 reviews)
"Everything was very clean and the amenities were great."

Reviewed on Mar 27, 2025

Embassy Suites by Hilton Fort Myers Estero
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 out of 5
1538 Cape Coral Pkwy E, Cape Coral, FL
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,007 reviews)
"This was great."

Reviewed on Mar 27, 2025

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Midtown

Fort Myers is a city that has a lot going on, but you have your sights set on Midtown. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Midtown has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Midtown hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Fort Myers so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Midtown underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Midtown city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Midtown cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Midtown at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $109
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Midtown hotel you want, book it, and never look back. Because your great escape is ahead of you.