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Hotels in Southwest Coast Florida

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Choose from 42471 Southwest Coast Florida Hotel Deals

Naples Grande Beach Resort
Naples Grande Beach Resort
4.5 out of 5
475 Seagate Drive, Naples, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 4.5-star luxury resort in Naples. Enjoy 3 outdoor pools, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,498 reviews)
"Nice place"

Reviewed on May 27, 2025

Naples Grande Beach Resort
Compass Hotel by Margaritaville Anna Maria Sound
Compass Hotel by Margaritaville Anna Maria Sound
4 out of 5
12324 Manatee Avenue West, Bradenton, FL
  • 41 min drive from Siesta Key Beach
Stay at this 4-star hotel in Bradenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.2/10 Wonderful! (1,447 reviews)
"I had an amazing time. The property was clean with an amazing staff. The food was very good. We had the marina view with the outdoor patio and we loved it."

Reviewed on May 27, 2025

Compass Hotel by Margaritaville Anna Maria Sound
Sunseeker Resort Charlotte Harbor
Sunseeker Resort Charlotte Harbor
4.5 out of 5
5500 Sunseeker Way, 785, Punta Gorda, FL
  • 1 hour drive from Siesta Key Beach
Stay at this 4.5-star luxury resort in Punta Gorda. Enjoy 2 outdoor pools, a full-service spa, and 7 restaurants. Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,018 reviews)
"I really enjoyed my stay here! Very beautiful rooms with a great view. I was hoping to see the sunset or sunrise from the harbor view rooms but you have to go up to the roof top pool to watch the sunset. It was still a very nice place with super nice staff!"

Reviewed on May 30, 2025

Sunseeker Resort Charlotte Harbor
Lani Kai Beachfront Resort
Lani Kai Beachfront Resort
3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 3.5-star beach hotel in Fort Myers Beach. Enjoy free WiFi, an outdoor pool, and a beach locale. Popular attractions Key West Express and Times Square ...
8.4/10 Very Good! (1,032 reviews)
"Great newly renovated resort. Location to walk to places and good customer service. Breakfast also pretty good for the resort. Just FYI need to pay for beach chairs and umbrellas but worth it."

Reviewed on May 28, 2025

Lani Kai Beachfront Resort
Margaritaville Beach Resort Fort Myers
Margaritaville Beach Resort Fort Myers
4 out of 5
251 Crescent Street, Fort Myers Beach, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 4-star beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,112 reviews)
"Best hotel in town"

Reviewed on May 29, 2025

Margaritaville Beach Resort Fort Myers
Tropical Beach Resorts
Tropical Beach Resorts
3.5 out of 5
6717 Sara Sea Circle, Siesta Key, FL
  • 27 min walk from Siesta Key Beach
Stay at this 3.5-star beach aparthotel in Siesta Key. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the pool and the helpful staff ...
9.2/10 Wonderful! (4,677 reviews)
"Been coming here for almost 15 years and you would think that they would be more kind at the front desk to repeat guests"

Reviewed on May 29, 2025

Tropical Beach Resorts
Sanibel Island Beach Resort
Sanibel Island Beach Resort
3 out of 5
1231 Middle Gulf Dr, Sanibel, FL
  • 2 hours drive from Siesta Key Beach
Stay at this 3-star beach hotel in Sanibel. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the pool and the restaurant in our reviews. ...
8.8/10 Excellent! (1,138 reviews)
"Great room. Everything almost perfect except for a few things missed by the vacuum- especially between the beds."

Reviewed on May 30, 2025

Sanibel Island Beach Resort
Hilton Naples
Hilton Naples
4 out of 5
5111 Tamiami Trl N, Naples, FL
  • 3 hours drive from Siesta Key Beach
Book a stay at this business-friendly hotel in Naples. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,087 reviews)
"Pretty"

Reviewed on May 28, 2025

Hilton Naples
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 out of 5
1538 Cape Coral Pkwy E, Cape Coral, FL
  • 2 hours drive from Siesta Key Beach
Book a stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,007 reviews)
"very good"

Reviewed on May 30, 2025

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Hilton Marco Island Beach Resort and Spa
Hilton Marco Island Beach Resort and Spa
4 out of 5
560 S Collier Blvd, Marco Island, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 4-star beach hotel in Marco Island. Enjoy a full-service spa, a beach locale, and room service. Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (1,375 reviews)
"It was a fantastic stay!"

Reviewed on May 30, 2025

Hilton Marco Island Beach Resort and Spa
Hyatt House Naples/5th Avenue
Hyatt House Naples/5th Avenue
3.5 out of 5
1345 5th Avenue South, Naples, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 3.5-star business-friendly hotel in Naples. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the breakfast and the pool in our reviews. ...
8.8/10 Excellent! (1,234 reviews)
"Really nice hotel with an amazing pool and very delicious Breakfast!!! We will definitely coming back !!"

Reviewed on May 27, 2025

Hyatt House Naples/5th Avenue
Compass by Margaritaville Hotel Naples
Compass by Margaritaville Hotel Naples
4 out of 5
4805 Tamiami Trl N, Naples, FL
  • 3 hours drive from Siesta Key Beach
Stay at this 4-star business-friendly hotel in Naples. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (773 reviews)
"I booked this hotel because I’ve never been to Naples, and I’m getting Married in June 2025. It was also my mom’s birthday and Mother’s Day weekend. When we got to the property it was excellent customer service and our room was cute, cozy, and stylish! Perfect for a quick getaway! We loved it so ..."

Reviewed on May 28, 2025

Compass by Margaritaville Hotel Naples
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southwest Coast Florida

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $132. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southwest Coast Florida hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southwest Coast Florida. No matter your reason for visiting Southwest Coast Florida, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southwest Coast Florida hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Southwest Coast Florida?

With over 42,471 hotels in Southwest Coast Florida, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $132.

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Finding a cheap car rental deal in Southwest Coast Florida is as easy as scoring cheap hotels in Southwest Coast Florida. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.