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Choose from 384 Panhandle Hotel Deals

The Cactus Cove Inn and Suites

The Cactus Cove Inn and Suites

2 out of 5
2501 E Interstate Dr Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,362 reviews)
Staff an owner was very accomodsting and hospitable. It is a unique placeto stay..if you are travelling wirh young ones,this is the hotel.indoor playground and pool..arcade and fish pond and fountain inside...rooms were very clean and spacious.

Reviewed on Apr 26, 2026

The Cactus Cove Inn and Suites
The Big Texan Motel

The Big Texan Motel

2.5 out of 5
7701 Interstate 40 Access Rd Amarillo TX
  • 54 min drive from Square House Museum
Stay at this motel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the pool and the restaurant in our reviews. Popular ...
9/10 Wonderful! (4,095 reviews)
Great motel! Super cute room with nice bed and pillows.

Reviewed on Apr 26, 2026

The Big Texan Motel
Spark by Hilton Amarillo Western Plaza

Spark by Hilton Amarillo Western Plaza

2.5 out of 5
12 Western Plaza Dr Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (332 reviews)
AC was goood and bed super comfy

Reviewed on Apr 26, 2026

Spark by Hilton Amarillo Western Plaza
Drury Inn & Suites Amarillo

Drury Inn & Suites Amarillo

3 out of 5
8540 W Interstate 40 Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,330 reviews)
It was my first stay at Drury and I am very satisfied with everything. Nice and clean room, good breakfast and friendly staff.

Reviewed on Apr 25, 2026

Drury Inn & Suites Amarillo
Yellow City Studios

Yellow City Studios

2 out of 5
6700 Interstate 40 Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Amarillo Botanical Gardens and ...
9/10 Wonderful! (282 reviews)
Staying in a suite for such a reasonable price was a treat!

Reviewed on Apr 25, 2026

Yellow City Studios
Holiday Inn Express & Suites Amarillo West by IHG

Holiday Inn Express & Suites Amarillo West by IHG

2.5 out of 5
8330 W Amarillo Blvd Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,179 reviews)
Breakfast was great. Rooms were clean.

Reviewed on Apr 24, 2026

Holiday Inn Express & Suites Amarillo West by IHG
Baymont by Wyndham Amarillo East

Baymont by Wyndham Amarillo East

2.5 out of 5
1700 I-40 E Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,691 reviews)
Very friendly and helpful staff

Reviewed on Apr 25, 2026

Baymont by Wyndham Amarillo East
Country Inn & Suites by Radisson, Amarillo I-40 West, TX

Country Inn & Suites by Radisson, Amarillo I-40 West, TX

3 out of 5
2000 Soncy Road Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (2,525 reviews)
Honestly, so much dirtier than I was expecting based on its 9/10 rating. I don’t mind an older hotel when it’s well maintained but this one left me feeling disappointed and very relieved we were there for only one night. Corners of the room were filled with dust and the walls have never been wiped ...

Reviewed on Apr 26, 2026

Country Inn & Suites by Radisson, Amarillo I-40 West, TX
La Quinta Inn by Wyndham Amarillo Mid-City

La Quinta Inn by Wyndham Amarillo Mid-City

3 out of 5
1708 I-40 E Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.4/10 Good! (1,521 reviews)
Nice cool room. The only thing I didn't like is that the shower had couple of hairs before our use.

Reviewed on Apr 26, 2026

La Quinta Inn by Wyndham Amarillo Mid-City
Atrea Inn Amarillo

Atrea Inn Amarillo

2.5 out of 5
2035 Paramount Blvd Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly motel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (2,326 reviews)
Its on a busy street ,some noise

Reviewed on Apr 24, 2026

Atrea Inn Amarillo
Best Western Plus Medical Center

Best Western Plus Medical Center

2.5 out of 5
7410 W Amarillo Blvd Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,059 reviews)
Very good choice

Reviewed on Apr 25, 2026

Best Western Plus Medical Center
Hyatt Place Amarillo-West

Hyatt Place Amarillo-West

3 out of 5
8985 W. AMARILLO BLVD Amarillo TX
  • 1 hour drive from Square House Museum
Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,404 reviews)
Clean great staff Great breakfast

Reviewed on Apr 26, 2026

Hyatt Place Amarillo-West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Panhandle

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How many hotels are there in Panhandle?

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