Search for Cheap Deals on
Hotels in Sedgewickville

Choose from 68 Sedgewickville Hotel Deals

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
2.5 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
  • 6 hours drive from Mississippi River
The price is $90 per night from Apr 15 to Apr 16
$90
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (532 reviews)
"Staff was so friendly and made me feel welcomed and comfortable"

Reviewed on Apr 11, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
2 out of 5
1119 Vincent Dr, Perryville, MO
  • 5 hours drive from Mississippi River
The price is $81 per night from May 4 to May 5
$81
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (844 reviews)
"The staff was very friendly and the guy at the front desk was helpful with ever thing we asked about hotel was nice clean and quiet. Thus was my second time staying at this same hotel"

Reviewed on Mar 30, 2025

Super 8 by Wyndham Perryville
Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $76 per night from Apr 15 to Apr 16
$76
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (562 reviews)
"It was okay"

Reviewed on Apr 7, 2025

Quality Inn
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3 out of 5
225 Drury Lane, Jackson, MO
  • 5 hours drive from Mississippi River
The price is $95 per night from Apr 18 to Apr 19
$95
includes taxes & fees
Apr 18 - Apr 19
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,001 reviews)
"Very accommodating and friendly staff! Helpful with stressful travelers😊 Great breakfast and evening kick back snacks and drinks!"

Reviewed on Apr 9, 2025

Drury Inn & Suites Jackson MO
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 out of 5
2520 Veterans Memorial Dr, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $115 per night from May 4 to May 5
$115
includes taxes & fees
May 4 - May 5
Stay at this hotel in Cape Girardeau. Enjoy free breakfast, free parking, and a fitness center. Popular attractions Cape Girardeau Conservation Nature Center ...
9.8/10 Exceptional! (7 reviews)
Very 21st century facility
"The manager wwnt above and beyond to make ua comfortable, the hotel had juat opened so everything was new and super clean, a very 21st century dwelling and very impressive The rooms however do not have cupboards and drawers for clothing and stuff, but overally it was nice."

Reviewed on Apr 12, 2025

Tru By Hilton Cape Girardeau
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHG
2.5 out of 5
2020 Jefferson St, Perryville, MO
  • 5 hours drive from Mississippi River
The price is $118 per night from Apr 20 to Apr 21
$118
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (455 reviews)
Sleep saver <3
"I was flooded out of going home after vacation. I was able to stay at the HIE through Hotels.com. The staff had me ready to go when I got there. They have amazing electric blinds to block the sunlight...I work nights."

Reviewed on Apr 10, 2025

Holiday Inn Express & Suites Perryville by IHG
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
  • 6 hours drive from Mississippi River
The price is $105 per night from Apr 15 to Apr 16
$105
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (699 reviews)
"Big room on the corner!!"

Reviewed on Apr 13, 2025

Comfort Suites Jackson-Cape Girardeau
Madison Inn Lodge
Madison Inn Lodge
2.5 out of 5
730 Plaza Drive, Fredericktown, MO
  • 5 hours drive from Mississippi River
The price is $93 per night from Apr 15 to Apr 16
$93
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly motel in Fredericktown. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in ...
7.4/10 Good! (271 reviews)
Time at Madison County Inn
"The room was nice. Everything was very clean. The bed was really comfy. The staff was helpful and polite.."

Reviewed on Feb 3, 2025

Madison Inn Lodge
Town House Inn
Town House Inn
2.5 out of 5
517 E Jackson Blvd, Jackson, MO
  • 6 hours drive from Mississippi River
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (392 reviews)
"Only negative was no ice in ice machine."

Reviewed on Mar 29, 2025

Town House Inn
Quality Inn Perryville I-55
Quality Inn Perryville I-55
2.5 out of 5
1517 S. Perryville Blvd., Perryville, MO
  • 5 hours drive from Mississippi River
The price is $92 per night from Apr 20 to Apr 21
$92
includes taxes & fees
Apr 20 - Apr 21
Stay at this hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and Saint Marys Lake are located ...
6.6/10 (98 reviews)
"Friendly staff. Close to gas station & food options."

Reviewed on Apr 4, 2025

Quality Inn Perryville I-55
Days Inn by Wyndham Perryville
Days Inn by Wyndham Perryville
2 out of 5
1500 Liberty Street, Perryville, MO
  • 5 hours drive from Mississippi River
The price is $90 per night from May 4 to May 5
$90
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
6.8/10 (396 reviews)
"Y"

Reviewed on Dec 30, 2024

Days Inn by Wyndham Perryville
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
3 out of 5
301 1st St, Marble Hill, MO
  • 6 hours drive from Mississippi River
The price is $113 per night from May 14 to May 15
$113
includes taxes & fees
May 14 - May 15
Stay at this 3-star hotel in Marble Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
9.6/10 Exceptional! (68 reviews)
"EC Reed had the nicest, most attentive staff of anywhere I have ever stayed. The room was very clean. The experience was very unique."

Reviewed on Mar 20, 2025

EC Reed's Mercantile and Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Sedgewickville

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Sedgewickville hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Sedgewickville.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Sedgewickville’s 68 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $76. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Sedgewickville hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Sedgewickville. No matter your reason for visiting Sedgewickville, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Sedgewickville hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Sedgewickville for as low as $76.

How many hotels are there in Sedgewickville?

With over 68 hotels in Sedgewickville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $76.

How to find cheap car rentals in Sedgewickville?

Finding a cheap car rental deal in Sedgewickville is as easy as scoring cheap hotels in Sedgewickville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.