Search for Cheap Deals on
Spa Resort Hotels in South Loop

Check Last Minute South Loop Hotel Deals

Tonight Apr 27 - Apr 28Next weekend May 3 - May 5

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!

Featured South Loop Resorts & Hotels with Spas

Bluegreen Vacations Hotel Blake, Ascend Resort Collection
Bluegreen Vacations Hotel Blake, Ascend Resort Collection
3.5 out of 5
500 South Dearborn Street, Chicago, IL
Fully refundableReserve now, pay when you stay
Stay at this boutique hotel in Chicago. Enjoy free WiFi, breakfast, and room service. Our guests praise the restaurant and the helpful staff in our reviews. ...
Bluegreen Vacations Hotel Blake, Ascend Resort Collection
Hilton Chicago
Hilton Chicago
4 out of 5
720 S Michigan Ave, Chicago, IL
Fully refundableReserve now, pay when you stay
Stay at this historic hotel in Chicago. Enjoy 2 restaurants, breakfast, and a health club. Our guests praise the pool and the helpful staff in our reviews. Popular ...
Hilton Chicago
Hyatt Regency McCormick Place
Hyatt Regency McCormick Place
4 out of 5
2233 S Martin Luther King Dr, Chicago, IL
Fully refundable
Stay at this business-friendly hotel in Chicago. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Hyatt Regency McCormick Place
See all 4,088 properties in South Loop
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.