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4 Star Hotels in Southwest Florida

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Featured 4 Star Southwest Florida Hotels

Hyatt Regency Sarasota
4 out of 5
Fully refundableReserve now, pay when you stay
  • 13 min drive from Siesta Key Beach
The price is $236 per night from May 11 to May 12
$236
includes taxes & fees
May 11 - May 12
Book a stay at this eco-certified hotel in Sarasota. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the pool and the helpful staff in ...
Hyatt Regency Sarasota
Margaritaville Beach Resort Fort Myers
4 out of 5
  • 2 hours drive from Siesta Key Beach
The price is $306 per night from Apr 27 to Apr 28
$306
includes taxes & fees
Apr 27 - Apr 28
Stay at this 4-star beach hotel in Fort Myers Beach. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff ...
Margaritaville Beach Resort Fort Myers
Sunseeker Resort Charlotte Harbor
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 1 hour drive from Siesta Key Beach
The price is $231 per night from May 1 to May 2
$231
includes taxes & fees
May 1 - May 2
Stay at this 4.5-star luxury resort in Punta Gorda. Enjoy 2 outdoor pools, a full-service spa, and 7 restaurants. Our guests praise the pool and the helpful ...
Sunseeker Resort Charlotte Harbor
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Naples Grande Beach Resort
4.5 out of 5
  • 3 hours drive from Siesta Key Beach
The price is $368 per night from May 26 to May 27
$368
includes taxes & fees
May 26 - May 27
Stay at this 4.5-star luxury resort in Naples. Enjoy 3 outdoor pools, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff ...
Naples Grande Beach Resort
DoubleTree by Hilton Sarasota Bradenton Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 22 min drive from Siesta Key Beach
The price is $129 per night from May 4 to May 5
$129
includes taxes & fees
May 4 - May 5
Stay at this 4-star business-friendly hotel in Sarasota. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
DoubleTree by Hilton Sarasota Bradenton Airport
Compass by Margaritaville Hotel Naples
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Siesta Key Beach
The price is $190 per night from May 4 to May 5
$190
includes taxes & fees
May 4 - May 5
Stay at this 4-star business-friendly hotel in Naples. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
Compass by Margaritaville Hotel Naples
The Westin Sarasota
4 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min drive from Siesta Key Beach
The price is $223 per night from May 11 to May 12
$223
includes taxes & fees
May 11 - May 12
Stay at this 4-star spa hotel in Sarasota. Enjoy a full-service spa, 2 restaurants, and a rooftop terrace. Our guests praise the breakfast and the pool in our ...
The Westin Sarasota
Inn on Fifth
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Siesta Key Beach
The price is $494 per night from May 18 to May 19
$494
includes taxes & fees
May 18 - May 19
Stay at this 4-star spa hotel in Naples. Enjoy a full-service spa, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
Inn on Fifth
Palmetto Marriott Resort & Spa
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 42 min drive from Siesta Key Beach
The price is $211 per night from May 4 to May 5
$211
includes taxes & fees
May 4 - May 5
Stay at this 4.5-star luxury hotel in Palmetto. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Popular attractions Palmetto Historical Park and Manatee ...
Palmetto Marriott Resort & Spa
Hilton Marco Island Beach Resort and Spa
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Siesta Key Beach
The price is $350 per night from May 26 to May 27
$350
includes taxes & fees
May 26 - May 27
Stay at this 4-star beach hotel in Marco Island. Enjoy a full-service spa, a beach locale, and room service. Our guests praise the pool and the restaurant in ...
Hilton Marco Island Beach Resort and Spa
JW Marriott Marco Island Beach Resort
4 out of 5
  • 3 hours drive from Siesta Key Beach
The price is $964 per night from May 4 to May 5
$964
includes taxes & fees
May 4 - May 5
Book a stay at this beach resort in Marco Island. Enjoy 3 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the property ...
JW Marriott Marco Island Beach Resort
The Perry Hotel Naples
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 3 hours drive from Siesta Key Beach
The price is $227 per night from Apr 29 to Apr 30
$227
includes taxes & fees
Apr 29 - Apr 30
Stay at this 4.5-star luxury hotel in Naples. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Popular attractions Vanderbilt Beach and Barefoot Beach are ...
The Perry Hotel Naples
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-star hotels in Southwest Florida

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in Southwest Florida for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in Southwest Florida as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag Southwest Florida 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in Southwest Florida starting at $129 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded Southwest Florida 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.