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5 Star Hotels in Santo Antonio

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Tonight Mar 28 - Mar 29This weekend Mar 28 - Mar 30

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Featured 5 Star Santo Antonio Hotels

EPIC SANA Marques Hotel
5 out of 5
  • 10 min walk from Avenida da Liberdade
The price is $263 per night from Mar 29 to Mar 30
$263
includes taxes & fees
Mar 29 - Mar 30
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
EPIC SANA Marques Hotel
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
5 out of 5
  • 2 min walk from Avenida da Liberdade
The price is $344 per night from Apr 23 to Apr 24
$344
includes taxes & fees
Apr 23 - Apr 24
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
EPIC SANA Lisboa Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
  • 11 min walk from Avenida da Liberdade
The price is $252 per night from Mar 29 to Mar 30
$252
includes taxes & fees
Mar 29 - Mar 30
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
EPIC SANA Lisboa Hotel
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Iberostar Selection Lisboa
5 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min walk from Avenida da Liberdade
The price is $203 per night from Apr 27 to Apr 28
$203
includes taxes & fees
Apr 27 - Apr 28
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean rooms ...
Iberostar Selection Lisboa
TURIM Boulevard Hotel – Adults Only
5 out of 5
  • 1 min walk from Avenida da Liberdade
The price is $193 per night from Mar 29 to Mar 30
$193
includes taxes & fees
Mar 29 - Mar 30
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, an outdoor pool, and 2 bars/lounges. Our guests praise the helpful staff and the property condition ...
TURIM Boulevard Hotel – Adults Only
Sofitel Lisbon Liberdade
5 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from Avenida da Liberdade
The price is $259 per night from Mar 30 to Mar 31
$259
includes taxes & fees
Mar 30 - Mar 31
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, an attached winery, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
Sofitel Lisbon Liberdade
Eurostars Das Letras
5 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from Avenida da Liberdade
The price is $169 per night from Mar 31 to Apr 1
$169
includes taxes & fees
Mar 31 - Apr 1
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...
Eurostars Das Letras
138 Liberdade Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from Avenida da Liberdade
The price is $249 per night from Mar 30 to Mar 31
$249
includes taxes & fees
Mar 30 - Mar 31
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in ...
138 Liberdade Hotel
PortoBay Liberdade
5 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from Avenida da Liberdade
The price is $282 per night from Mar 31 to Apr 1
$282
includes taxes & fees
Mar 31 - Apr 1
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in ...
PortoBay Liberdade
The Vintage Hotel & Spa - Lisbon
5 out of 5
Fully refundableReserve now, pay when you stay
  • 4 min walk from Avenida da Liberdade
The price is $336 per night from Mar 31 to Apr 1
$336
includes taxes & fees
Mar 31 - Apr 1
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the bar and the helpful staff in our reviews. ...
The Vintage Hotel & Spa - Lisbon
Altis Grand Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from Avenida da Liberdade
The price is $270 per night from Apr 5 to Apr 6
$270
includes taxes & fees
Apr 5 - Apr 6
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms in ...
Altis Grand Hotel
Browns Avenue Hotel
5 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from Avenida da Liberdade
Stay at this 5-star luxury hotel in Lisbon. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
Browns Avenue Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5-Star Hotel in Santo Antonio

It’s time. No more meh motels and so-so stays. This vacation it’s all about living it up, and that starts with a great hotel. You want first-class service and award-winning restaurants. Well, let us introduce you to a 5-star hotel in Santo Antonio.

So nice you’ll blink twice

What makes a hotel worthy of supreme star-age? For starters, the service has to be top-notch and personalized. These hotels often have 24-hour room service, a welcome gift upon your arrival, and help you with your bags—even if you travel light.

Are they nicer? Heck yeah, they are! Most 5-star hotels have jaw-dropping aesthetics that give an authentic feel of class. And we’re not talking about that faux-gold soap dish your Aunt Tilda puts out for the guests—it’s the real deal.

Stars in your eyes

Are 5-stars hotels worth it? If you like the finer things in life, then yes, they sure are. But we also know you’re the type that likes to get your caviar on a fish stick budget. We’re right there with you, and that is why we make it easy to find the best 5-star hotel in Santo Antonio for you. Sort by:

  • Price: Want to live large, but keep that budget balanced? We got you. We have 5-star hotels starting at $169.

  • Amenities: Santo Antonio skyline view? Maybe a heated indoor pool? Looking for a Michelin-star restaurant? Search for the hotels that have the amenities you desire.

  • Hotwire Hot Rate: We’ll tell you the name of the hotel after you book, and you might just save a ton.

When you’re looking for the top 5-star hotels in Santo Antonio—but don’t want to pay top dollar—let us help you out. You can get that posh palace of your dreams, and have money left to take on Santo Antonio your way.